Author details

Full Name

Lawrence F Bielak

Affiliation

ORCID

Career Start Year

1994

Papers

143

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37291111	Author Correction: Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.	Nat Commun	2023
38028628	Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.	Front Genet	2023
37662265	WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.	medRxiv	2023
38014529	Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis.	Circ Genom Precis Med	2023
37804200	Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk.	J Am Heart Assoc	2023
37709864	Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease.	Nat Genet	2023
37770635	Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.	Nat Genet	2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
37398003	Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.	medRxiv	2023
36702996	Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.	Nat Genet	2023
36748836	Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity.		2023
35085396	Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts.	Diabetes Care	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
35534559	Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects.	Nat Genet	2022
36477530	Genetic diversity fuels gene discovery for tobacco and alcohol use.	Nature	2022
35039093	Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA).	Clin Epigenetics	2022
35179313	Multivariate, region-based genetic analyses of facets of reproductive aging in White and Black women.	Mol Genet Genomic Med	2022
34415308	Epigenome-wide association study of mitochondrial genome copy number.	Hum Mol Genet	2021
34241534	Multiethnic Genome-Wide Association Study of Subclinical Atherosclerosis in Individuals With Type 2 Diabetes.	Circ Genom Precis Med	2021
33856023	Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction.	Hum Mol Genet	2021
33846329	Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.	Nat Commun	2021
33727701	Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2021
33726838	Epigenetic age acceleration is associated with cardiometabolic risk factors and clinical cardiovascular disease risk scores in African Americans.	Clin Epigenetics	2021
33878091	Associations between polygenic risk score for age at menarche and menopause, reproductive timing, and serum hormone levels in multiple race/ethnic groups.	Menopause	2021
33558525	Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
33713608	Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.	Am J Hum Genet	2021
33547301	Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.	Nat Commun	2021
33100131	Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans.	Epigenetics	2021
33402679	Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
35036986	Association of mitochondrial DNA copy number with cardiometabolic diseases.	Cell Genom	2021
34385354	Population sequencing data reveal a compendium of mutational processes in the human germ line.	Science	2021
34604815	Genetic discovery and risk characterization in type 2 diabetes across diverse populations.	HGG Adv	2021
34488438	Epidemiologic and Genetic Associations of Erythropoietin With Blood Pressure, Hypertension, and Coronary Artery Disease.	Hypertension	2021
32510982	Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels.	Circ Genom Precis Med	2020
32379818	Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose.	PLoS One	2020
31687759	Western Dietary Pattern Derived by Multiple Statistical Methods Is Prospectively Associated with Subclinical Carotid Atherosclerosis in Midlife Women.	Journal of Nutrition	2020
32871381	Fetal and early postnatal lead exposure measured in teeth associates with infant gut microbiota.	Environ Int	2020
33339817	Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.	Nat Commun	2020
33230300	Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2020
30936141	A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease.	Diabetes	2019
31719535	Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.	Nat Commun	2019
31291324	Prospective associations between beverage intake during the midlife and subclinical carotid atherosclerosis: The Study of Women's Health Across the Nation.	PLoS ONE	2019
31127295	A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.	Hum Mol Genet	2019
30735952	In utero metal exposures measured in deciduous teeth and birth outcomes in a racially-diverse urban cohort.	Environ Res	2019
31160809	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2019
31334442	Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes.	Hepatol Commun	2019
30854262	Genetics of Subclinical Coronary Atherosclerosis.	Curr Genet Med Rep	2018
28958070	Relationships of Clinical and Computed Tomography-Imaged Adiposity with Cognition in Middle-Aged and Older African Americans.	J Gerontol A Biol Sci Med Sci	2018
30297969	Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.	Nat Genet	2018
29912962	Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.	PLoS One	2018