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Author Details

Michael R Freeman
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
1987
211
60
PMIDPaper TitleJournal TitlePublished Year
37964070Genetic and biological drivers of prostate cancer disparities in Black men.Nat Rev Urol2024
38082056The effects of glycemic index on prostate cancer progression in a xenograft mouse model.Prostate Cancer Prostatic Dis2024
36625255ONECUT2 regulates RANKL-dependent enterocyte and microfold cell differentiation in the small intestine; a multi-omics study.Nucleic Acids Res2023
37905039ONECUT2 Activates Diverse Resistance Drivers of Androgen Receptor-Independent Heterogeneity in Prostate Cancer.bioRxiv2023
37484909Autonomous action and cooperativity between the ONECUT2 transcription factor and its 3' untranslated region.Front Cell Dev Biol2023
37761978Targeting Key Players of Neuroendocrine Differentiation in Prostate Cancer.Int J Mol Sci2023
36959101Targeting Glutamine Metabolism in Prostate Cancer.Front Biosci (Elite Ed)2023
37398277The homeodomain drives favorable DNA binding energetics of prostate cancer target ONECUT2.bioRxiv2023
34728526Cholesterol-Lowering Intervention Decreases mTOR Complex 2 Signaling and Enhances Antitumor Immunity.Clin Cancer Res2022
35638091Variation in Molecularly Defined Prostate Tumor Subtypes by Self-identified Race.Eur Urol Open Sci2022
36636695Activation of ONECUT2 by RB1 loss in castration-resistant prostate cancer.Am J Clin Exp Urol2022
35115556Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis.Nat Commun2022
34897998BoxCar and shotgun proteomic analyses reveal molecular networks regulated by UBR5 in prostate cancer.Proteomics2022
32986127Antioxidant functions of DHHC3 suppress anti-cancer drug activities.Cell Mol Life Sci2021
33531653A comparative study of PCS and PAM50 prostate cancer classification schemes.Prostate Cancer Prostatic Dis2021
34552338Clinical Utility of Olaparib in the Treatment of Metastatic Castration-Resistant Prostate Cancer: A Review of Current Evidence and Patient Selection.Onco Targets Ther2021
34541033Loss of CDCP1 triggers FAK activation in detached prostate cancer cells.Am J Clin Exp Urol2021
34541032Scaffold attachment factor B1 regulates androgen degradation pathways in prostate cancer.Am J Clin Exp Urol2021
33402390A Transcriptional Regulatory Loop of Master Regulator Transcription Factors, PPARG, and Fatty Acid Synthesis Promotes Esophageal Adenocarcinoma.Cancer Res2021
33037017Comparative Genomics Reveals Distinct Immune-oncologic Pathways in African American Men with Prostate Cancer.Clin Cancer Res2021
32373127Sex as a Determinant of Responses to a Coronary Artery Disease Self-Antigen Identified by Immune-Peptidomics.Front Immunol2020
31844180Validation of a genomic classifier for prediction of metastasis and prostate cancer-specific mortality in African-American men following radical prostatectomy in an equal access healthcare setting.Prostate Cancer Prostatic Dis2020
3201981027-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6-JAK-STAT3 Signaling in Prostate Cancer Cells.Mol Cancer Res2020
32944167Comprehensive palmitoyl-proteomic analysis identifies distinct protein signatures for large and small cancer-derived extracellular vesicles.J Extracell Vesicles2020
32631766Combination Androgen Receptor Inhibition and Docetaxel in Metastatic Castration-sensitive Prostate Cancer: The Next Step in First-line Treatment?Clin Genitourin Cancer2020
32380981Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential.BMC Cancer2020
30566156A scalable filtration method for high throughput screening based on cell deformability.Lab Chip2019
35117025ONECUT2 as a new therapeutic target in androgen receptor-indifferent prostate cancer.Transl Cancer Res2019
31839905Large and small extracellular vesicles released by glioma cells in vitro and in vivo.J Extracell Vesicles2019
31244925A Circulating Tumor Cell-RNA Assay for Assessment of Androgen Receptor Signaling Inhibitor Sensitivity in Metastatic Castration-Resistant Prostate Cancer.Theranostics2019
31251020Low-Background Acyl-Biotinyl Exchange Largely Eliminates the Coisolation of Non-S-Acylated Proteins and Enables Deep S-Acylproteomic Analysis.Anal Chem2019
30811493Keratin 8 is a potential self-antigen in the coronary artery disease immunopeptidome: A translational approach.PLoS One2019
31011308Quantitative proteomic analysis of prostate tissue specimens identifies deregulated protein complexes in primary prostate cancer.Clin Proteomics2019
31022216Optimization of DNA extraction from human urinary samples for mycobiome community profiling.PLoS One2019
29282360Serum cholesterol and risk of high-grade prostate cancer: results from the REDUCE study.Prostate Cancer Prostatic Dis2018
30154147Emerin Deregulation Links Nuclear Shape Instability to Metastatic Potential.Cancer Res2018
30177293Statin Therapy to Improve Prostate Cancer Outcomes: Who, When, and for How Long?Eur Urol2018
29930975Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model.Cell Mol Gastroenterol Hepatol2018
30108686Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma.J Extracell Vesicles2018
30314329Identification of the Transcription Factor Relationships Associated with Androgen Deprivation Therapy Response and Metastatic Progression in Prostate Cancer.Cancers (Basel)2018
30478421ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis.Nat Med2018
29752463Personalization of prostate cancer therapy through phosphoproteomics.Nat Rev Urol2018
29511352Regulation of inside-out β1-integrin activation by CDCP1.Oncogene2018
29795142Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer.Prostate Cancer Prostatic Dis2018
29556354Genes involved in prostate cancer progression determine MRI visibility.Theranostics2018
27858503High-throughput sequencing of two populations of extracellular vesicles provides an mRNA signature that can be detected in the circulation of breast cancer patients.RNA Biol2017
28130224CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer.Cancer Res2017
28202510MYC Mediates Large Oncosome-Induced Fibroblast Reprogramming in Prostate Cancer.Cancer Res2017
29212854A Systems Approach to Prostate Cancer Classification-Response.Cancer Res2017
27900797Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model.Prostate2017
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Collaborators

Dolores Di Vizio
Cedars-Sinai Medical Center
Co-authored papers 41
Sungyong You
Cedars-Sinai Medical Center
Co-authored papers 38
Stephen J Freedland
Cedars-Sinai Medical Center
Co-authored papers 23
Edwin M Posadas
Cedars-Sinai Medical Center
Co-authored papers 14
Beatrice S Knudsen
University of Utah
Co-authored papers 12
Hanno Steen
Boston Children's Hospital, USA Harvard Medical School, Harvard Medical School
Co-authored papers 11
Francesca Demichelis
University of Trento
Co-authored papers 8
Mark A Rubin
University of Bern
Co-authored papers 7
Kristine Pelton
Co-authored papers 7
David Zurakowski
Harvard Medical School, Boston Children's Hospital
Co-authored papers 7
Isla P Garraway
David Geffen School of Medicine University of California Los Angeles
Co-authored papers 6
Minhyung Kim
Roswell Park Comprehensive Cancer Center
Co-authored papers 6
Sara Pollan
Cedars-Sinai Medical Center 8700 Beverly Blvd
Co-authored papers 5
Elai Davicioni
Veracyte Inc.
Co-authored papers 5
Massimo Loda
Weill Medical College of Cornell University
Co-authored papers 5
Daehee Hwang
Co-authored papers 4
Robert B Den
Thomas Jefferson University Hospital
Co-authored papers 4
Eric A Klein
Cleveland Clinic
Co-authored papers 4
Robert Jeffrey Karnes
Mayo Clinic
Co-authored papers 4
Leigh Ellis
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
Co-authored papers 4
Bruce J Trock
Johns Hopkins University School of Medicine
Co-authored papers 3
Colm Morrissey
Co-authored papers 3
Hsian-Rong Tseng
Jonsson Comprehensive Cancer Center, University of California los angeles
Co-authored papers 3
Yang Liu
Veracyte inc.
Co-authored papers 3
Elahe A Mostaghel
University of Washington
Co-authored papers 3
Javier Mariscal
Samuel Oschin Comprehensive Cancer Institute
Co-authored papers 3
Jie-Fu Chen
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Angeline S Ferdinand
Co-authored papers 2
Beth Y Karlan
David Geffen School of Medicine, University of California los angeles
Co-authored papers 2
Leonora Balaj
Massachusetts General Hospital
Co-authored papers 2
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