Skip to Main Content

Author Details

Philip L De Jager
Columbia University Medical Center
1995
484
110
PMIDPaper TitleJournal TitlePublished Year
37425698SR-TWAS: Leveraging Multiple Reference Panels to Improve TWAS Power by Ensemble Machine Learning.medRxiv2024
37961373Frequency of Variants in Mendelian Alzheimer's Disease Genes within the Alzheimer's Disease Sequencing Project (ADSP).medRxiv2024
38050142ZCCHC17 Modulates Neuronal RNA Splicing and Supports Cognitive Resilience in Alzheimer's Disease.J Neurosci2024
37425698SR-TWAS: Leveraging Multiple Reference Panels to Improve TWAS Power by Ensemble Machine Learning.medRxiv2024
37961373Frequency of Variants in Mendelian Alzheimer's Disease Genes within the Alzheimer's Disease Sequencing Project (ADSP).medRxiv2024
38050142ZCCHC17 Modulates Neuronal RNA Splicing and Supports Cognitive Resilience in Alzheimer's Disease.J Neurosci2024
36335579Fragmentation of rest periods, astrocyte activation, and cognitive decline in older adults with and without Alzheimer's disease.Alzheimers Dement2023
36335579Fragmentation of rest periods, astrocyte activation, and cognitive decline in older adults with and without Alzheimer's disease.Alzheimers Dement2023
36448302Not all roads lead to the immune system: the genetic basis of multiple sclerosis severity.Brain2023
37679407Evaluating genomic signatures of aging in brain tissue as it relates to Alzheimer's disease.Sci Rep2023
38036778Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings.Nat Genet2023
38036535Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.Nat Commun2023
38016942INPP5D regulates inflammasome activation in human microglia.Nat Commun2023
37891690Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer's disease at CPT1A locus.Clin Epigenetics2023
37961425Identification of a specific APOE transcript and functional elements associated with Alzheimer's disease.medRxiv2023
37961404A public resource of single cell transcriptomes and multiscale networks from persons with and without Alzheimer's disease.bioRxiv2023
37693521Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project.medRxiv2023
37693453Key variants via Alzheimer's Disease Sequencing Project whole genome sequence data.medRxiv2023
37689213Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment.Neurobiol Dis2023
37283765Differential impact of environmental factors on systemic and localized autoimmunity.Front Immunol2023
36905877Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease.Neurobiol Aging2023
36778249Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts.bioRxiv2023
36966244TREM2 gene expression associations with Alzheimer's disease neuropathology are region-specific: implications for cortical versus subcortical microglia.Acta Neuropathol2023
37398494The MIND diet, brain transcriptomic alterations, and dementia.medRxiv2023
37336975Multicellular communities are perturbed in the aging human brain and Alzheimer's disease.Nat Neurosci2023
37082508Multi-omic integration via similarity network fusion to detect molecular subtypes of ageing.Brain Commun2023
37333223Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.medRxiv2023
37131588Genetic insights into the association between inflammatory bowel disease and Alzheimer's disease.medRxiv2023
36945609Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer's disease.bioRxiv2023
36811307Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease.Alzheimers Dement2023
36697247Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease.Neurology2023
36747803Multi-region brain transcriptomes uncover two subtypes of aging individuals with differences in Alzheimer risk and the impact of <i>APOEε4</i>.bioRxiv2023
37440260Primacy and recency effects in verbal memory are differentially associated with post-mortem frontal cortex p-tau 217 and 202 levels in a mixed sample of community-dwelling older adults.J Clin Exp Neuropsychol2023
36865313Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer's disease risk gene SORL1.bioRxiv2023
36993746ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease.bioRxiv2023
36993652Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings.bioRxiv2023
36865139INPP5D/SHIP1 regulates inflammasome activation in human microglia.bioRxiv2023
37177846Associations of VGF with Neuropathologies and Cognitive Health in Older Adults.Ann Neurol2023
36993271Novel <i>CYP1B1-RMDN2</i> Alzheimer's disease locus identified by genome-wide association analysis of cerebral tau deposition on PET.medRxiv2023
36462719The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms.Neurobiol Dis2023
37533636A structured evaluation of cryopreservation in generating single-cell transcriptomes from cerebrospinal fluid.Cell Rep Methods2023
37034737A single-nucleus transcriptome-wide association study implicates novel genes in depression pathogenesis.medRxiv2023
38016942INPP5D regulates inflammasome activation in human microglia.Nat Commun2023
37961425Identification of a specific APOE transcript and functional elements associated with Alzheimer's disease.medRxiv2023
37961404A public resource of single cell transcriptomes and multiscale networks from persons with and without Alzheimer's disease.bioRxiv2023
37891690Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer's disease at CPT1A locus.Clin Epigenetics2023
37693521Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project.medRxiv2023
37693453Key variants via Alzheimer's Disease Sequencing Project whole genome sequence data.medRxiv2023
37689213Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment.Neurobiol Dis2023
37679407Evaluating genomic signatures of aging in brain tissue as it relates to Alzheimer's disease.Sci Rep2023
  • 1 - 50 of 968

Recommended Authors

NIHR Maudsley Biomedical Research Centre, King's College London
Career Start Year 2016
Number of shared co-authors 12
Brigham Young University
Career Start Year 2014
Number of shared co-authors 34
University of Oslo, Regeneron Pharmaceuticals
Career Start Year 2014
Number of shared co-authors 111
UK Dementia Research Institute, Imperial College London
Career Start Year 2014
Number of shared co-authors 63
Center for Statistical Genetics, University of Michigan ann arbor
Career Start Year 2014
Number of shared co-authors 10
Larner College of Medicine, University of Vermont
Career Start Year 2011
Number of shared co-authors 4
University of California San Diego
Career Start Year 2008
Number of shared co-authors 42
Duke University
Career Start Year 2007
Number of shared co-authors 36
University of Wisconsin Madison
Career Start Year 2004
Number of shared co-authors 21
College of Science, The Australian National University
Career Start Year 2004
Number of shared co-authors 3
King's College London
Career Start Year 2003
Number of shared co-authors 126
Feinstein Institutes for Medical Research
Career Start Year 2003
Number of shared co-authors 13
Imperial College London
Career Start Year 2003
Number of shared co-authors 47
Center for Multimodal Imaging and Genetics, University of California
Career Start Year 2003
Number of shared co-authors 17
Boston University School of Public Health
Career Start Year 2001
Number of shared co-authors 241
David Geffen School of Medicine
Career Start Year 2001
Number of shared co-authors 50
University of Minnesota
Career Start Year 2001
Number of shared co-authors 131
Center for Multimodal Imaging and Genetics, University of California San Diego
Career Start Year 2001
Number of shared co-authors 58
University of Pennsylvania
Career Start Year 2001
Number of shared co-authors 84
University of Washington
Career Start Year 2000
Number of shared co-authors 20
University of California san francisco
Career Start Year 2000
Number of shared co-authors 70
NIHR Maudsley Biomedical Research Centre, King's College London
Career Start Year 2000
Number of shared co-authors 87
The State University of New Jersey
Career Start Year 1998
Number of shared co-authors 141
Duke University School of Medicine
Career Start Year 1998
Number of shared co-authors 19
William Harvey Research Institute, Queen Mary University of London
Career Start Year 1997
Number of shared co-authors 188
The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University
Career Start Year 1997
Number of shared co-authors 51
Massachusetts General Hospital
Career Start Year 1996
Number of shared co-authors 27
John P. Hussman Institute for Human Genomics.
Career Start Year 1994
Number of shared co-authors 66
Johns Hopkins School of Medicine
Career Start Year 1992
Number of shared co-authors 46
Mayo Clinic
Career Start Year 1988
Number of shared co-authors 46

Collaborators

Rush University Medical Center
Co-authored papers 255
Rush University Medical Center
Co-authored papers 97
Yale School of Medicine, Yale School of Public Health
Co-authored papers 60
Co-authored papers 57
Cleveland Institute for Computational Biology, Case Western Reserve University
Co-authored papers 43
University of Tennessee College of Medicine Chattanooga
Co-authored papers 42
Co-authored papers 39
Columbia University Irving Medical Center
Co-authored papers 38
Co-authored papers 34
University of Oxford
Co-authored papers 34
Baylor College of Medicine
Co-authored papers 34
Co-authored papers 32
Co-authored papers 31
Harvard T.H. Chan School of Public Health
Co-authored papers 31
University of Michigan School of Public Health ann arbor
Co-authored papers 30
Co-authored papers 30
SUNY Upstate Medical University
Co-authored papers 30
Erasmus University Medical Center
Co-authored papers 28
National Institute on Aging
Co-authored papers 26
Co-authored papers 26
Columbia University Irving Medical Center, New York Presbyterian Hospital
Co-authored papers 26
Co-authored papers 25
Pacific Northwest National Laboratory
Co-authored papers 24
Co-authored papers 24
Co-authored papers 24
Co-authored papers 23
Co-authored papers 23
Co-authored papers 23
Co-authored papers 23
Mayo Clinic
Co-authored papers 23