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Author Details

David J Friedman
1995
83
36
PMIDPaper TitleJournal TitlePublished Year
36920755Inaxaplin for Proteinuric Kidney Disease in Persons with Two <i>APOL1</i> Variants.N Engl J Med2023
36328101Estimated Versus Measured Glomerular Filtration Rate in Men at Risk for Mesoamerican Nephropathy.Am J Kidney Dis2023
36449077Apolipoprotein L1 (APOL1) cation current in HEK-293 cells and in human podocytes.Pflugers Arch2023
38036523Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease.Nat Commun2023
37068179Urinary Metabolomic Profile of Youth at Risk of Chronic Kidney Disease in Nicaragua.Kidney3602023
37113494APOL1 and APOL1-Associated Kidney Disease: A Common Disease, an Unusual Disease Gene - Proceedings of the Henry Shavelle Professorship.2023
37041408Heat stress and heat strain among outdoor workers in El Salvador and Nicaragua.2023
36789382Point-of-Care Testing in Chronic Kidney Disease of Non-Traditional Origin: Considerations for Clinical, Epidemiological, and Health Surveillance Research and Practice.2023
36984765Metabolic Features of Increased Gut Permeability, Inflammation, and Altered Energy Metabolism Distinguish Agricultural Workers at Risk for Mesoamerican Nephropathy.Metabolites2023
35232775DGAT2 Inhibition Potentiates Lipid Droplet Formation To Reduce Cytotoxicity in APOL1 Kidney Risk Variants.J Am Soc Nephrol2022
35894278Treatment potential in APOL1-associated nephropathy.Current Opinion in Nephrology and Hypertension2022
36282916ADAR regulates APOL1 via A-to-I RNA editing by inhibition of MDA5 activation in a paradoxical biological circuit.Proc Natl Acad Sci U S A2022
35794550High prevalence of chronic kidney disease of unknown etiology among workers in the Mesoamerican Nephropathy Occupational Study.BMC Nephrology2022
36415326COVID-19 and CKD: Employment, Food Security and Healthcare in El Salvador.Annals of Global Health2022
34929253A glomerular transcriptomic landscape of apolipoprotein L1 in Black patients with focal segmental glomerulosclerosis.Kidney Int2022
32504218Biomarkers of kidney injury among children in a high-risk region for chronic kidney disease of uncertain etiology.Pediatr Nephrol2021
34350953Recessive, gain-of-function toxicity in an APOL1 BAC transgenic mouse model mirrors human APOL1 kidney disease.Dis Model Mech2021
33288631COVID-19 and APOL1: Understanding Disease Mechanisms through Clinical Observation.Journal of the American Society of Nephrology : JASN2021
32616495APOL1 Nephropathy: From Genetics to Clinical Applications.Clinical journal of the American Society of Nephrology : CJASN2021
32958645Circulating testican-2 is a podocyte-derived marker of kidney health.Proc Natl Acad Sci U S A2020
31992573The Genetic Architecture of Kidney Disease.Clinical journal of the American Society of Nephrology : CJASN2020
31710572and Kidney Disease: From Genetics to Biology.Annual Review of Physiology2020
32707746Urinary Metals Concentrations and Biomarkers of Autoimmunity among Navajo and Nicaraguan Men.International Journal of Environmental Research and Public Health2020
32817310Racial and Ethnic Disparities in Seasonal Influenza Vaccination among Dialysis Facilities in the United States.J Am Soc Nephrol2020
30826087Prevalence and Risk Factors for CKD Among Brickmaking Workers in La Paz Centro, Nicaragua.American Journal of Kidney Diseases2019
31835714Comment on Sarathkumara et al.: Exposure to Hantavirus is a Risk Factor Associated with Kidney Diseases in Sri Lanka: A Cross Sectional Study.Viruses2019
31580460APOL1 gene variants and kidney disease in whites: the cardiovascular health study.Nephrol Dial Transplant2019
31558683APOL1 Kidney Risk Variants Induce Cell Death <i>via</i> Mitochondrial Translocation and Opening of the Mitochondrial Permeability Transition Pore.J Am Soc Nephrol2019
31611067Apolipoprotein L1 (APOL1) risk variant toxicity depends on the haplotype background.Kidney Int2019
30451737Genes and environment in chronic kidney disease hotspots.Current Opinion in Nephrology and Hypertension2019
30733285Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity.Proc Natl Acad Sci U S A2019
31054623Genetic and Developmental Factors in Chronic Kidney Disease Hotspots.Seminars in Nephrology2019
31317114APOL1-Associated Kidney Disease in Brazil.Kidney International Reports2019
31309920Investigating Possible Infectious Causes of Chronic Kidney Disease of Unknown Etiology in a Nicaraguan Mining Community.American Journal of Tropical Medicine and Hygiene2019
31308072Contributions of Rare Gene Variants to Familial and Sporadic FSGS.J Am Soc Nephrol2019
29513073Modulation of tubular solute reuptake in UMOD knockout mice.Am J Physiol Renal Physiol2018
28339911A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy.Nephrol Dial Transplant2018
30596165The Glomerular Disease Study and Trial Consortium: A Grassroots Initiative to Foster Collaboration and Innovation.Kidney Int Rep2018
29866461Exome Sequencing for CKD Diagnosis: Coming Soon to a Clinic Near You?American Journal of Kidney Diseases2018
30042041Acute Kidney Injury in Sugarcane Workers at Risk for Mesoamerican Nephropathy.American Journal of Kidney Diseases2018
29531077<i>UBD</i> modifies <i>APOL1</i>-induced kidney disease risk.Proc Natl Acad Sci U S A2018
27932478Most ApoL1 Is Secreted by the Liver.J Am Soc Nephrol2017
29110757A Brief History of APOL1: A Gene Evolving.Seminars in Nephrology2017
27575010Characterization of Mesoamerican Nephropathy in a Kidney Failure Hotspot in Nicaragua.Am J Kidney Dis2016
26947522Apolipoprotein L1 and Kidney Disease in African Americans.Trends in Endocrinology and Metabolism2016
26945671Structural characterization of the C-terminal coiled-coil domains of wild-type and kidney disease-associated mutants of apolipoprotein L1.FEBS J2016
26311057Urine biomarkers of kidney injury among adolescents in Nicaragua, a region affected by an epidemic of chronic kidney disease of unknown aetiology.Nephrol Dial Transplant2016
26634651APOL1 Genotype, Kidney and Cardiovascular Disease, and Death in Older Adults.Arterioscler Thromb Vasc Biol2016
26699492APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases.Proc Natl Acad Sci U S A2016
25100047Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1.Kidney Int2015
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