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Author Details

Stuart A Ralph
Bio21 Molecular Science and Biotechnology Institute, University of Melbourne
2001
97
49
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36775128Conservation, abundance, glycosylation profile, and localization of the TSP protein family in Cryptosporidium parvum.J Biol Chem2023
37366629Nonsense-mediated decay machinery in <i>Plasmodium falciparum</i> is inefficient and non-essential.mSphere2023
35167626Chromosome-level genome of Schistosoma haematobium underpins genome-wide explorations of molecular variation.PLoS Pathog2022
35466042The AAA+ ATPase p97 as a novel parasite and tuberculosis drug target.Trends Parasitol2022
355525413, 2, 1, go! Cryptosporidium counts down to sex.PLoS Biol2022
34460304The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite.Antimicrob Agents Chemother2021
33906926Functional Characterization of the m<sup>6</sup>A-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite.mBio2021
33821563Non-canonical metabolic pathways in the malaria parasite detected by isotope-tracing metabolomics.Mol Syst Biol2021
32179747PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes.Nat Commun2020
32359872K13, the Cytostome, and Artemisinin Resistance.Trends Parasitol2020
307158823,3'-Disubstituted 5,5'-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity.J Med Chem2019
31775055Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance.Cell Rep2019
31271672Plasmodium sexual differentiation: how to make a female.Mol Microbiol2019
31318858Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking.PLoS Biol2019
31427248Delayed Death by Plastid Inhibition in Apicomplexan Parasites.Trends Parasitol2019
31370870Alternative splicing is required for stage differentiation in malaria parasites.Genome Biol2019
30782661Alternative Splicing in Apicomplexan Parasites.mBio2019
29509772The cysteine protease dipeptidyl aminopeptidase 3 does not contribute to egress of Plasmodium falciparum from host red blood cells.PLoS One2018
30212465Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites.PLoS Biol2018
30228310Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome.Nat Commun2018
28923023Comparative transcriptomics of female and male gametocytes in Plasmodium berghei and the evolution of sex in alveolates.BMC Genomics2017
28288098Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.Nat Microbiol2017
28205319The Plasmodium rhoptry associated protein complex is important for parasitophorous vacuole membrane structure and intraerythrocytic parasite growth.Cell Microbiol2017
26150544Metabolic Dysregulation Induced in Plasmodium falciparum by Dihydroartemisinin and Other Front-Line Antimalarial Drugs.J Infect Dis2016
27793563Targeting Protein Translation in Organelles of the Apicomplexa.Trends Parasitol2016
27800551Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles.ACS Cent Sci2016
27147296Characterization of a hepatitis C virus-like particle vaccine produced in a human hepatocyte-derived cell line.J Gen Virol2016
27289273Artemisinin Action and Resistance in Plasmodium falciparum.Trends Parasitol2016
27572396Metabolomics-Based Screening of the Malaria Box Reveals both Novel and Established Mechanisms of Action.Antimicrob Agents Chemother2016
27373602Large scale production of a mammalian cell derived quadrivalent hepatitis C virus like particle vaccine.J Virol Methods2016
27277538Selective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparum.Sci Rep2016
25689481Targeting and function of proteins mediating translation initiation in organelles of Plasmodium falciparum.Mol Microbiol2015
26198663Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase is a potential drug target.FEBS J2015
25870410A serine-arginine-rich (SR) splicing factor modulates alternative splicing of over a thousand genes in Toxoplasma gondii.Nucleic Acids Res2015
24428730A dual-targeted aminoacyl-tRNA synthetase in Plasmodium falciparum charges cytosolic and apicoplast tRNACys.Biochem J2014
24850912Reduced ribosomes of the apicoplast and mitochondrion of Plasmodium spp. and predicted interactions with antibiotics.Open Biol2014
23331966Cryo-electron tomography reveals four-membrane architecture of the Plasmodium apicoplast.Malar J2013
24596663Aminoacyl-tRNA synthetases as drug targets in eukaryotic parasites.Int J Parasitol Drugs Drug Resist2013
24058559An FtsH protease is recruited to the mitochondrion of Plasmodium falciparum.PLoS One2013
24225851Chronic arsenic exposure and microbial drug resistance.Proc Natl Acad Sci U S A2013
23614815Recycling factors for ribosome disassembly in the apicoplast and mitochondrion of Plasmodium falciparum.Mol Microbiol2013
23461734Electron tomography of Plasmodium falciparum merozoites reveals core cellular events that underpin erythrocyte invasion.Cell Microbiol2013
22116064TDR Targets: a chemogenomics resource for neglected diseases.Nucleic Acids Res2012
24533280In silico prediction of antimalarial drug target candidates.Int J Parasitol Drugs Drug Resist2012
23181666Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum.Genome Biol2012
22995720Determination of protein subcellular localization in apicomplexan parasites.Trends Parasitol2012
23049965Subcompartmentalisation of proteins in the rhoptries correlates with ordered events of erythrocyte invasion by the blood stage malaria parasite.PLoS One2012
22719945Investigation of the Plasmodium falciparum food vacuole through inducible expression of the chloroquine resistance transporter (PfCRT).PLoS One2012
22844982Malaria parasite signal peptide peptidase is an ER-resident protease required for growth but not for invasion.Traffic2012
22253438Biosynthesis, localization, and macromolecular arrangement of the Plasmodium falciparum translocon of exported proteins (PTEX).J Biol Chem2012
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Collaborators

The University of Melbourne
Co-authored papers 22
University of Pennsylvania
Co-authored papers 6
Burnet Institute
Co-authored papers 5
Peter MacCallum Cancer Centre
Co-authored papers 4
Wellcome Sanger Institute
Co-authored papers 4
Macquarie University
Co-authored papers 3
Everett Community College
Co-authored papers 3
King Abdullah University of Science and Technology
Co-authored papers 3
J. Craig Venter Institute
Co-authored papers 3
Center for Computational Biology, Johns Hopkins University
Co-authored papers 3
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 3
Co-authored papers 3
Universidad Nacional de San Martin
Co-authored papers 3
Center for Genomics and Systems Biology
Co-authored papers 3
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 3
Earlham Institute
Co-authored papers 3
Personal Genome Diagnostics Inc.
Co-authored papers 3
Julius-Maximilians-Universitat Wurzburg
Co-authored papers 3
AGORA Cancer Research Center
Co-authored papers 3
CSIR - National Chemical Laboratory
Co-authored papers 3
Center for Emerging and Re-emerging Infectious Diseases, University of Washington
Co-authored papers 3
International Livestock Research Institute (ILRI)
Co-authored papers 3
Institute of Integrative Biology, University of Liverpool
Co-authored papers 2
The J. Craig Venter Institute
Co-authored papers 2
Co-authored papers 2
Institut fur Biochemie und Molekularbiologie, Universitat Freiburg
Co-authored papers 2
Co-authored papers 2
Broad Institute of MIT and Harvard
Co-authored papers 2
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 2
Center for Biomolecular Science and Engineering, University of California
Co-authored papers 2