Author details

Full Name

William Lee

Affiliation

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35609568	A phenome-wide association study identifies effects of copy-number variation of VNTRs and multicopy genes on multiple human traits.	Am J Hum Genet	2022
28181494	Microenvironment-derived factors driving metastatic plasticity in melanoma.	Nat Commun	2017
35172488	Persistent Severe Hyperlactatemia and Metabolic Derangement in Lethal SDHB-Mutated Metastatic Kidney Cancer: Clinical Challenges and Examples of Extreme Warburg Effect.	JCO Precis Oncol	2017
28329682	The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma.	Cell Rep	2017
28614790	Genomic landscape and evolution of metastatic chromophobe renal cell carcinoma.	JCI Insight	2017
30334004	Genomic Alterations and Outcomes with VEGF-Targeted Therapy in Patients with Clear Cell Renal Cell Carcinoma.	Kidney Cancer	2017
28299801	Bi-allelic alterations in DNA repair genes underpin homologous recombination DNA repair defects in breast cancer.	J Pathol	2017
28249590	Erratum to: Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures.	Genome Biol	2017
27751729	Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma.	Eur Urol	2017
28173755	Melanoma genome evolution across species.	BMC Genomics	2017
27713405	Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets.	Nat Commun	2016
27282637	IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation.	Sci Rep	2016
27165745	Integrated Genomics for Pinpointing Survival Loci within Arm-Level Somatic Copy Number Alterations.	Cancer Cell	2016
26901439	Mitochondrial DNA copy number variation across human cancers.	Elife	2016
26766592	An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma.	Cancer Cell	2016
27855702	Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures.	Genome Biol	2016
27646943	Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors.	J Clin Oncol	2016
27601542	Phase II Trial and Correlative Genomic Analysis of Everolimus Plus Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma.	J Clin Oncol	2016
26061751	Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.	N Engl J Med	2015
25592567	Integrative genome-wide analysis of the determinants of RNA splicing in kidney renal clear cell carcinoma.	Pac Symp Biocomput	2015
25765070	Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer.	Science	2015
26444240	Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.	Nature	2015
26282170	A Quantitative System for Studying Metastasis Using Transparent Zebrafish.	Cancer Res	2015
25240281	PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors.	Nat Genet	2014
25261935	Genome-wide analysis of noncoding regulatory mutations in cancer.	Nat Genet	2014
25642447	Unraveling the molecular genetics of head and neck cancer through genome-wide approaches.	Genes Dis	2014
25083786	Remodeling of the methylation landscape in breast cancer metastasis.	PLoS One	2014
23685749	The mutational landscape of adenoid cystic carcinoma.	Nat Genet	2013
23926198	Genomics traces carcinogen fingerprints.	Sci Transl Med	2013
23033341	Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.	Genome Res	2012
22267523	The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients.	Genome Res	2012
20505728	The mutation spectrum revealed by paired genome sequences from a lung cancer patient.	Nature	2010
20011534	Bi-directional SIFT predicts a subset of activating mutations.	PLoS ONE	2009
19434427	Analytical methods for inferring functional effects of single base pair substitutions in human cancers.	Human Genetics	2009
18420932	The chemical genomic portrait of yeast: uncovering a phenotype for all genes.	Science	2008
17873876	A high-resolution atlas of nucleosome occupancy in yeast.	Nat Genet	2007
16121259	Genome-wide requirements for resistance to functionally distinct DNA-damaging agents.	PLoS Genet	2005
14990797	Codon usage between genomes is constrained by genome-wide mutational processes.	Proceedings of the National Academy of Sciences of the United States of America	2004