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Author Details

Meghna Das Thakur
2006
38
19
PMIDPaper TitleJournal TitlePublished Year
36921494Clinical and exploratory biomarker findings from the MODUL trial (Cohorts 1, 3 and 4) of biomarker-driven maintenance therapy for metastatic colorectal cancer.2023
37903590Comparison of SP263 and 22C3 immunohistochemistry PD-L1 assays for clinical efficacy of adjuvant atezolizumab in non-small cell lung cancer: results from the randomized phase III IMpower010 trial.2023
34689413Extracellular vesicle production in Gram-positive bacteria.Microbial Biotechnology2022
35364611Novel Anti-LY6G6D/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Colorectal Cancer.Molecular Cancer Therapeutics2022
35416705Controlled Proteolysis of an Essential Virulence Determinant Dictates Infectivity of Lyme Disease Pathogens.Infection and Immunity2022
36265119Tumor Fraction Correlates With Detection of Actionable Variants Across > 23,000 Circulating Tumor DNA Samples.JCO Precision Oncology2022
35660252Immune contexture of paediatric cancers.Eur J Cancer2022
35190375Clinical efficacy of atezolizumab plus bevacizumab and chemotherapy in mutated non-small cell lung cancer with , or comutations: subgroup results from the phase III IMpower150 trial.Journal for ImmunoTherapy of Cancer2022
34433583Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition.Gut2022
34972191Transcriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B.PLoS ONE2021
33637813Investigating BB0405 as a novel Borrelia afzelii vaccination candidate in Lyme borreliosis.Scientific Reports2021
33241650Pan-cancer population pharmacokinetics and exposure-safety and -efficacy analyses of atezolizumab in patients with high tumor mutational burden.Pharmacology Research and Perspectives2020
32103181Peripheral T cell expansion predicts tumour infiltration and clinical response.Nature2020
30918950Phase Ib study of atezolizumab combined with cobimetinib in patients with solid tumors.Ann Oncol2019
31781549Enzymatic Bioremediation of Organophosphate Compounds-Progress and Remaining Challenges.Frontiers in Bioengineering and Biotechnology2019
29934966Borrelia burgdorferi protein interactions critical for microbial persistence in mammals.Cellular Microbiology2019
29350463BRIM-P: A phase I, open-label, multicenter, dose-escalation study of vemurafenib in pediatric patients with surgically incurable, BRAF mutation-positive melanoma.Pediatric Blood and Cancer2018
29032550Analysis of Borrelia burgdorferi Proteome and Protein-Protein Interactions.Methods in Molecular Biology2018
29991973Pseudoprogression of CNS metastatic disease of alveolar soft part sarcoma during anti-PDL1 treatment.Radiology Case Reports2018
29763623Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial.Cancer Cell2018
28963370Eukaryotic-type serine/threonine kinase mediated phosphorylation at Thr perturbs mycobacterial guanylate kinase activity.Bioscience Reports2017
28592866A protein-protein interaction dictates Borrelial infectivity.Scientific Reports2017
27271745HtrA, a Temperature- and Stationary Phase-Activated Protease Involved in Maturation of a Key Microbial Virulence Determinant, Facilitates Borrelia burgdorferi Infection in Mammalian Hosts.Infect Immun2016
25542447Ligand-independent EPHA2 signaling drives the adoption of a targeted therapy-mediated metastatic melanoma phenotype.Cancer Discov2015
24335187Variola virus E3L Zα domain, but not its Z-DNA binding activity, is required for PKR inhibition.RNA2014
24122209Mouse tumour models to guide drug development and identify resistance mechanisms.Journal of Pathology2014
24352648Molecular pathways: response and resistance to BRAF and MEK inhibitors in BRAF(V600E) tumors.Clinical Cancer Research2014
23302800Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance.Nature2013
24097822The evolution of melanoma resistance reveals therapeutic opportunities.Cancer Research2013
23063529eIF2γ mutation that disrupts eIF2 complex integrity links intellectual disability to impaired translation initiation.Molecular Cell2012
20303269Ajuba LIM proteins are negative regulators of the Hippo signaling pathway.Current Biology2010
21382592A multifunctional lentiviral-based gene knockdown with concurrent rescue that controls for off-target effects of RNAi.2010
20970745Regulation of U6 promoter activity by transcriptional interference in viral vector-based RNAi.2010
18805675Evidence for the presence of R250G mutation at the ATPase domain of topoisomerase II in an arsenite-resistant Leishmania donovani exhibiting a differential drug inhibition profile.International Journal of Antimicrobial Agents2009
18557704Ability of PknA, a mycobacterial eukaryotic-type serine/threonine kinase, to transphosphorylate MurD, a ligase involved in the process of peptidoglycan biosynthesis.Biochemical Journal2008
17827231Endothelial cell migration on RGD-peptide-containing PEG hydrogels in the presence of sphingosine 1-phosphate.Biophys J2008
18199749Interdomain interaction reconstitutes the functionality of PknA, a eukaryotic type Ser/Thr kinase from Mycobacterium tuberculosis.J Biol Chem2008
17068335GTPase activity of mycobacterial FtsZ is impaired due to its transphosphorylation by the eukaryotic-type Ser/Thr kinase, PknA.Journal of Biological Chemistry2006
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