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Author Details
Full Name
Joseph Torchia
Affiliation
Western University
ORCID
Career Start Year
1985
Papers
58
H Index
29
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
35159032
The Role of Thymine DNA Glycosylase in Transcription, Active DNA Demethylation, and Cancer.
Cancers (Basel)
2022
36551676
Regulation of Chromatin Accessibility by the Farnesoid X Receptor Is Essential for Circadian and Bile Acid Homeostasis In Vivo.
Cancers (Basel)
2022
33444292
Disrupting the DREAM transcriptional repressor complex induces apolipoprotein overexpression and systemic amyloidosis in mice.
J Clin Invest
2021
32268085
Loss of Thymine DNA Glycosylase Causes Dysregulation of Bile Acid Homeostasis and Hepatocellular Carcinoma.
Cell Rep
2020
32944627
TDG is a novel tumor suppressor of liver malignancies.
Mol Cell Oncol
2020
30697731
TBX3 promotes progression of pre-invasive breast cancer cells by inducing EMT and directly up-regulating SLUG.
J Pathol
2019
31359394
Mapping Retinoic Acid-Dependant 5mC Derivatives in Mouse Embryonic Fibroblasts.
Methods Mol Biol
2019
29378668
Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization.
Epigenetics Chromatin
2018
28538185
Regulation of Active DNA Demethylation through RAR-Mediated Recruitment of a TET/TDG Complex.
Cell Rep
2017
29069809
Human papillomavirus dysregulates the cellular apparatus controlling the methylation status of H3K27 in different human cancers to consistently alter gene expression regardless of tissue of origin.
Oncotarget
2017
24115386
Critical components of the pluripotency network are targets for the p300/CBP interacting protein (p/CIP) in embryonic stem cells.
Stem Cells
2014
23434684
β-Estradiol-dependent activation of the JAK/STAT pathway requires p/CIP and CARM1.
Biochim Biophys Acta
2013
22623781
Cellular GCN5 is a novel regulator of human adenovirus E1A-conserved region 3 transactivation.
J Virol
2012
22956576
Regulation of B cell linker protein transcription by PU.1 and Spi-B in murine B cell acute lymphoblastic leukemia.
J Immunol
2012
22704620
Adenovirus evasion of interferon-mediated innate immunity by direct antagonism of a cellular histone posttranslational modification.
Cell Host Microbe
2012
22560925
TGF-β-dependent active demethylation and expression of the p15ink4b tumor suppressor are impaired by the ZNF217/CoREST complex.
Mol Cell
2012
21914189
Regulation of the BRCA1 gene by an SRC3/53BP1 complex.
BMC Biochem
2011
19966277
Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase.
Nucleic Acids Res
2010
21057087
Regulation of follicular B cell differentiation by the related E26 transformation-specific transcription factors PU.1, Spi-B, and Spi-C.
J Immunol
2010
20144788
Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation.
Cell Stem Cell
2010
19129215
Transcriptional control by adenovirus E1A conserved region 3 via p300/CBP.
Nucleic Acids Res
2009
19381935
Biochemical analysis of arginine methylation in transcription.
Methods Mol Biol
2009
18625718
Genome analysis identifies the p15ink4b tumor suppressor as a direct target of the ZNF217/CoREST complex.
Mol Cell Biol
2008
18524818
Identification of a second CtBP binding site in adenovirus type 5 E1A conserved region 3.
J Virol
2008
17130829
Biochemical characterization of the zinc-finger protein 217 transcriptional repressor complex: identification of a ZNF217 consensus recognition sequence.
Oncogene
2007
17043108
The activity and stability of the transcriptional coactivator p/CIP/SRC-3 are regulated by CARM1-dependent methylation.
Mol Cell Biol
2007
17073437
Direct association between the CREB-binding protein (CBP) and nuclear receptor corepressor (N-CoR).
Biochemistry
2006
15281178
Food, water, and the PVS patient.
Natl Cathol Bioeth Q
2004
12813456
Interaction of the HPV E7 proteins with the pCAF acetyltransferase.
Oncogene
2003
15038386
Artificial hydration and nutrition for the PVS patient: ordinary care or extraordinary intervention?
Natl Cathol Bioeth Q
2003
12885766
The coactivator p/CIP/SRC-3 facilitates retinoic acid receptor signaling via recruitment of GCN5.
J Biol Chem
2003
14599792
The E1A proteins of all six human adenovirus subgroups target the p300/CBP acetyltransferases and the SAGA transcriptional regulatory complex.
Virology
2003
11864601
Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription.
Mol Cell
2002
12854583
Postmodernism and the persistent vegetative state.
Natl Cathol Bioeth Q
2002
12192059
Microtubule-dependent subcellular redistribution of the transcriptional coactivator p/CIP.
Mol Cell Biol
2002
12024042
Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex.
Mol Cell Biol
2002
12105181
Requirement for RAR-mediated gene repression in skeletal progenitor differentiation.
J Cell Biol
2002
12077342
Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes.
Mol Cell Biol
2002
11554326
Isolation of a p300/CBP cointegrator-associated protein coactivator complex.
Methods Mol Biol
2001
11013263
A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1.
J Biol Chem
2000
9808623
Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation.
Genes Dev
1998
9445475
Transcription factor-specific requirements for coactivators and their acetyltransferase functions.
Science
1998
9445474
Differential use of CREB binding protein-coactivator complexes.
Science
1998
9501191
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes.
Proc Natl Acad Sci U S A
1998
9640539
Co-activators and co-repressors in the integration of transcriptional responses.
Curr Opin Cell Biol
1998
9139820
A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression.
Nature
1997
9192892
The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function.
Nature
1997
9191164
Mechanisms of transcriptional activation by retinoic acid receptors.
Biochem Soc Trans
1997
8616895
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors.
Cell
1996
7566114
Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor.
Nature
1995
1 - 50 of 58
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