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Author Details

Dorit Donoviel
Translational Research Institute for Space Health
1988
37
22
Vardit Ravitsky (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37534923Reimagining scientific conferences-a Keystone Symposia report.Ann N Y Acad Sci2023
37663891Nourishing the brain on deep space missions: nutritional psychiatry in promoting resilience.Front Neural Circuits2023
37769066Ethically cleared to launch?Science2023
35318465Establishment of an open biomedical database for commercial spaceflight.Nat Med2022
36336356Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel.Life Sci Space Res (Amst)2022
33397500Microbiome for Mars: surveying microbiome connections to healthcare with implications for long-duration human spaceflight, virtual workshop, July 13, 2020.Microbiome2021
29562964Internal Jugular Vein Volume During Head-Down Tilt and Carbon Dioxide Exposure in the SPACECOT Study.Aerosp Med Hum Perform2018
30020056Quantitative Pupillometry for Detection of Intracranial Pressure Changes During Head-Down Tilt.Aerosp Med Hum Perform2018
29357516Effects of -12° head-down tilt with and without elevated levels of CO<sub>2</sub> on cognitive performance: the SPACECOT study.J Appl Physiol (1985)2018
28890152Re: Leapman et al.: Up and Away: Five Decades of Urologic Investigation in Microgravity (Urology 106:18-25).Urology2017
28209740Quantitative MRI volumetry, diffusivity, cerebrovascular flow, and cranial hydrodynamics during head-down tilt and hypercapnia: the SPACECOT study.J Appl Physiol (1985)2017
28235859An international collaboration studying the physiological and anatomical cerebral effects of carbon dioxide during head-down tilt bed rest: the SPACECOT study.J Appl Physiol (1985)2017
28641684Novel Indications for Commonly Used Medications as Radiation Protectants in Spaceflight.Aerosp Med Hum Perform2017
26724629Clinical Validation of a Transcranial Doppler-Based Noninvasive Intracranial Pressure Meter: A Prospective Cross-Sectional Study.World Neurosurg2016
25811362Noninvasive Brain Physiology Monitoring for Extreme Environments: A Critical Review.J Neurosurg Anesthesiol2015
25401937The impact of sex and gender on adaptation to space: executive summary.J Womens Health (Larchmt)2014
18719666High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes.Obesity (Silver Spring)2008
16300640A presenilin-independent aspartyl protease prefers the gamma-42 site cleavage.J Neurochem2006
16474849Functional characterization of novel presenilin-2 variants identified in human breast cancers.Oncogene2006
16204356Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling.FASEB J2005
12684521Presenilin-1 and presenilin-2 exhibit distinct yet overlapping gamma-secretase activities.J Biol Chem2003
12619154Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.Genes Chromosomes Cancer2003
11756438Identification and characterization of presenilin-independent Notch signaling.J Biol Chem2002
12036937mdmx is a negative regulator of p53 activity in vivo.Cancer Res2002
11937492Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells.Genes Dev2002
11891288Notch receptor cleavage depends on but is not directly executed by presenilins.Proc Natl Acad Sci U S A2002
11416156Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN.Mol Cell Biol2001
11773604Optical dysfunction of the crystalline lens in aquaporin-0-deficient mice.Physiol Genomics2001
11146649Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.Nat Cell Biol2000
10878814Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1.Nat Cell Biol2000
10557208Mice lacking both presenilin genes exhibit early embryonic patterning defects.Genes Dev1999
10051412SEL-1L maps to human chromosome 14, near the insulin-dependent diabetes mellitus locus 11.Genomics1999
9858735Cloning and characterization of Sel-1l, a murine homolog of the C. elegans sel-1 gene.Mech Dev1998
9419413Embryonic and adult expression patterns of the Tec tyrosine kinase gene suggest a role in megakaryocytopoiesis, blood vessel development, and melanogenesis.Cell Growth Differ1997
8657140Analysis of muscle creatine kinase gene regulatory elements in skeletal and cardiac muscles of transgenic mice.Mol Cell Biol1996
2211838Thrombospondin gene expression is associated with mitogenesis in 3T3 cells: induction by basic fibroblast growth factor.J Cell Physiol1990
2848801Structural analysis and expression of the human thrombospondin gene promoter.J Biol Chem1988
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Collaborators

Johns Hopkins University
Co-authored papers 3
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Co-authored papers 2
Merck & Co. Inc.
Co-authored papers 2
Cambridge Institute for Medical Research, University of Cambridge
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
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Tsudanuma Neurology Clinic.
Co-authored papers 1
Dalla Lana School of Public Health, University of Toronto
Co-authored papers 1
University of Washington School of Medicine
Co-authored papers 1
University Health Network, Princess Margaret Cancer Centre
Co-authored papers 1
Johns Hopkins University, Berman Institute of Bioethics
Co-authored papers 1
Cambridge Institute for Medical Research, University of Cambridge
Co-authored papers 1
Faculty of Law and School of Public Health, University of Alberta
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
The Hastings Center
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
University of California
Co-authored papers 1
The Center for Law and the Biosciences, Stanford University
Co-authored papers 1
Co-authored papers 1
University of Texas Health Science Center
Co-authored papers 1
Center for Air and Space Law, University of Mississippi
Co-authored papers 1
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Princess Margaret Cancer Centre, University Health Network
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University of Toronto
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University of Toronto
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Petrie-Flom Center for Health Law Policy, Harvard University
Co-authored papers 1