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Author Details

Joshua D Rabinowitz
Lewis Sigler Institute for Integrative Genomics, Princeton University
1996
294
103
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36725930Slow TCA flux and ATP production in primary solid tumours but not metastases.Nature2023
37756255Acidic Methanol Treatment Facilitates Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Imaging of Energy Metabolism.Anal Chem2023
37961420One-carbon unit supplementation fuels tumor-infiltrating T cells and augments checkpoint blockade.bioRxiv2023
37802078Comprehensive quantification of metabolic flux during acute cold stress in mice.Cell Metab2023
37907620Metabolic pathway analysis using stable isotopes in patients with cancer.Nat Rev Cancer2023
38065083Systematic identification and characterization of genes in the regulation and biogenesis of photosynthetic machinery.Cell2023
37788990An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis.Nat Commun2023
37612403The pentose phosphate pathway in health and disease.Nat Metab2023
37646579Dichloroacetate as a novel pharmaceutical treatment for cancer-related fatigue in melanoma.Am J Physiol Endocrinol Metab2023
37930434Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome.Basic Res Cardiol2023
37728660Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade.Cancer Discov2023
37873106G6PD Maintains Redox Homeostasis and Biosynthesis in LKB1-Deficient KRAS-Driven Lung Cancer.bioRxiv2023
37186827Impact of acute stress on murine metabolomics and metabolic flux.Proc Natl Acad Sci U S A2023
37410734Tissue-specific reprogramming of glutamine metabolism maintains tolerance to sepsis.PLoS One2023
37169877Reply to: revisiting the role of serine metabolism in hepatic lipogenesis.Nat Metab2023
37100997Branched-chain amino acid catabolism in muscle affects systemic BCAA levels but not insulin resistance.Nat Metab2023
37401371Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells.Dis Model Mech2023
36711816Glycine homeostasis requires reverse SHMT flux.bioRxiv2023
36603705Comparative study of two Saccharomyces cerevisiae strains with kinetic models at genome-scale.Metab Eng2023
36602953Correction: Novel Pyrrolo[3,2-d]Pyrimidine Compounds Target Mitochondrial and Cytosolic One-Carbon Metabolism with Broad-spectrum Antitumor Efficacy.Mol Cancer Ther2023
36860699Metabolic engineering of low-pH-tolerant non-model yeast, <i>Issatchenkia orientalis</i>, for production of citramalate.Metab Eng Commun2023
34767747MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function.Immunity2022
35857842G6PD-mediated increase in de novo NADP<sup>+</sup> biosynthesis promotes antioxidant defense and tumor metastasis.Sci Adv2022
35759301Impaired Lymphocyte Responses in Pediatric Sepsis Vary by Pathogen Type and are Associated with Features of Immunometabolic Dysregulation.Shock2022
35425930Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth.Med2022
36776621Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy.Nat Cardiovasc Res2022
36525649Photoproximity Labeling of Sialylated Glycoproteins (GlycoMap) Reveals Sialylation-Dependent Regulation of Ion Transport.J Am Chem Soc2022
35970997Glucose feeds the tricarboxylic acid cycle via excreted ethanol in fermenting yeast.Nat Chem Biol2022
36070684Metabolite Exchange between Mammalian Organs Quantified in Pigs.Cell Metab2022
36223763Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure.Cell Metab2022
35916672Selenium Modulates Cancer Cell Response to Pharmacologic Ascorbate.Cancer Res2022
36376563Myeloid-derived itaconate suppresses cytotoxic CD8<sup>+</sup> T cells and promotes tumour growth.Nat Metab2022
35132243Spatially resolved isotope tracing reveals tissue metabolic activity.Nat Methods2022
35058631Circulating metabolite homeostasis achieved through mass action.Nat Metab2022
35108511Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction.Cell Metab2022
34706266GCN2 adapts protein synthesis to scavenging-dependent growth.Cell Syst2022
34715056Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors.Cell Chem Biol2022
34624079SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.Blood2022
32382081SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia.Leukemia2021
33756105mTORC1 promotes cell growth via m<sup>6</sup>A-dependent mRNA degradation.Mol Cell2021
33887198The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine.Cell Metab2021
35121870Publisher Correction: Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response.Nat Cancer2021
34588310A genetic model of methionine restriction extends <i>Drosophila</i> health- and lifespan.Proc Natl Acad Sci U S A2021
34788087Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition.Sci Adv2021
34571983CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production.Cells2021
34799699Methionine synthase supports tumour tetrahydrofolate pools.Nat Metab2021
34845393Serine catabolism generates liver NADPH and supports hepatic lipogenesis.Nat Metab2021
34414571Metabolic decisions in development and disease-a Keystone Symposia report.Ann N Y Acad Sci2021
34711973Metabolite discovery through global annotation of untargeted metabolomics data.Nat Methods2021
34559996NAD<sup>+</sup> flux is maintained in aged mice despite lower tissue concentrations.Cell Syst2021
  • 1 - 50 of 294

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Collaborators

Yi-Fan Xu
Nanjing Hydraulic Research Institute
Co-authored papers 12
Xiaoyang Su
Cancer Institute of New Jersey
Co-authored papers 11
David Botstein
Calico Life Sciences LLC
Co-authored papers 10
Zemer Gitai
Princeton University
Co-authored papers 8
Tomer Shlomi
Technion-Israel Institute of Technology
Co-authored papers 7
Mark M Davis
Co-authored papers 6
Hilary A Coller
Co-authored papers 6
Marcus Bosenberg
Yale School of Medicine
Co-authored papers 4
Marcia C Haigis
Co-authored papers 4
David H Perlman
Co-authored papers 4
Norbert Perrimon
Co-authored papers 4
Lewis C Cantley
Co-authored papers 4
Markus Ralser
Charite - Universitatsmedizin Berlin
Co-authored papers 4
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Geisel School of Medicine at Dartmouth
Co-authored papers 3
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Transplant Research Center, Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 3
Jason W Locasale
Duke University
Co-authored papers 3
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Co-authored papers 3
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Harvard Medical School
Co-authored papers 3
Shawn R Campagna
Co-authored papers 3
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Johns Hopkins University School of Medicine
Co-authored papers 3
Joseph H Gorman
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Olga G Troyanskaya
Lewis-Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 2
Ravindra Majeti
Stanford University School of Medicine
Co-authored papers 2
Carl H June
University of Pennsylvania Department of Pathology & Laboratory Medicine
Co-authored papers 2
Tyler Jacks
Co-authored papers 2
Ian A Blair
Co-authored papers 2
Yuval Kluger
Yale University School of Medicine
Co-authored papers 2
F Kyle Satterstrom
Co-authored papers 2
Robert C Gorman
University of Pennsylvania
Co-authored papers 2
Alexei Savchenko
University of Toronto
Co-authored papers 2
Release 1.2