Skip to Main Content

Author Details

George R Bousfield
Wichita State University
1982
75
29
PMIDPaper TitleJournal TitlePublished Year
37240364Follicle-Stimulating Hormone Biological Products: Does Potency Predict Clinical Efficacy?Int J Mol Sci2023
37905087Differential effects of follicle-stimulating hormone glycoforms on the transcriptome profile of cultured rat granulosa cells as disclosed by RNA-seq.bioRxiv2023
37870089Oocyte quality is enhanced by hypoglycosylated FSH through increased cell-to-cell interaction during mouse follicle development.Development2023
36201606Follicle-Stimulating Hormone Glycosylation Variants Distinctly Modulate Pre-antral Follicle Growth and Survival.Endocrinology2022
36329887Human FSH Glycoform α-Subunit Asparagine<sup>52</sup> Glycans: Major Glycan Structural Consistency, Minor Glycan Variation in Abundance.Front Endocrinol (Lausanne)2022
34059912Hypo-glycosylated hFSH drives ovarian follicular development more efficiently than fully-glycosylated hFSH: enhanced transcription and PI3K and MAPK signaling.Hum Reprod2021
33897975FGDB: Database of follicle stimulating hormone glycans.Comput Struct Biotechnol J2021
34925235Differential FSH Glycosylation Modulates FSHR Oligomerization and Subsequent cAMP Signaling.Front Endocrinol (Lausanne)2021
32342021In Vitro Impact of FSH Glycosylation Variants on FSH Receptor-stimulated Signal Transduction and Functional Selectivity.J Endocr Soc2020
32942611Glycoprotein G-protein Coupled Receptors in Disease: Luteinizing Hormone Receptors and Follicle Stimulating Hormone Receptors.Diseases2020
32553947Bioactivity of recombinant hFSH glycosylation variants in primary cultures of porcine granulosa cells.Mol Cell Endocrinol2020
31127275Follicle-Stimulating Hormone Glycobiology.Endocrinology2019
31600726Recombinant FSH glycoforms are bioactive in mouse preantral ovarian follicles.Reproduction2019
29867757<i>In Vivo</i> and <i>In Vitro</i> Impact of Carbohydrate Variation on Human Follicle-Stimulating Hormone Function.Front Endocrinol (Lausanne)2018
26911932A human FSHB transgene encoding the double N-glycosylation mutant (Asn(7ο) Asn(24ο)) FSHβ subunit fails to rescue Fshb null mice.Mol Cell Endocrinol2016
27561202Evaluation of in vivo bioactivities of recombinant hypo- (FSH<sup>21/18</sup>) and fully- (FSH<sup>24</sup>) glycosylated human FSH glycoforms in Fshb null mice.Mol Cell Endocrinol2016
25796287The recombinant equine LHβ subunit combines divergent intracellular traits of human LHβ and CGβ subunits.Theriogenology2015
26402790Glycosylation Effects on FSH-FSHR Interaction Dynamics: A Case Study of Different FSH Glycoforms by Molecular Dynamics Simulations.PLoS One2015
25915568Hypoglycosylated hFSH Has Greater Bioactivity Than Fully Glycosylated Recombinant hFSH in Human Granulosa Cells.J Clin Endocrinol Metab2015
25960929Comparison of Follicle-Stimulating Hormone Glycosylation Microheterogenity by Quantitative Negative Mode Nano-Electrospray Mass Spectrometry of Peptide-N Glycanase-Released Oligosaccharides.J Glycomics Lipidomics2015
25661536Production, purification, and characterization of recombinant hFSH glycoforms for functional studies.Mol Cell Endocrinol2015
24139927Editorial for the MCE special issue on "Novel endocrine mechanisms in the regulation of reproduction".Mol Cell Endocrinol2014
25893134Naturally Occurring Follicle-Stimulating Hormone Glycosylation Variants.J Glycomics Lipidomics2014
25722940Macro- and Micro-heterogeneity in Pituitary and Urinary Follicle-Stimulating Hormone Glycosylation.J Glycomics Lipidomics2014
24931192Constitutive activity in gonadotropin receptors.Adv Pharmacol2014
24291635Hypo-glycosylated human follicle-stimulating hormone (hFSH(21/18)) is much more active in vitro than fully-glycosylated hFSH (hFSH(24)).Mol Cell Endocrinol2014
23351732Trafficking of the follitropin receptor.Methods Enzymol2013
21739108Synthesis and secretion of gonadotropins including structure-function correlates.Rev Endocr Metab Disord2011
21603090GlycomicsDB - A Data Integration Platform for Glycans and their Strucutres.Open Med Inform J2011
20107152Partially deglycosylated equine LH preferentially activates beta-arrestin-dependent signaling at the follicle-stimulating hormone receptor.Mol Endocrinol2010
18197704Chromatofocusing fails to separate hFSH isoforms on the basis of glycan structure.Biochemistry2008
17049590Expression and bioactivity of a single chain recombinant equine luteinizing hormone (reLH).Theriogenology2007
17079072All-or-none N-glycosylation in primate follicle-stimulating hormone beta-subunits.Mol Cell Endocrinol2007
16478110Method for characterizing sulfated glycoproteins in a glycosylation site-specific fashion, using ion pairing and tandem mass spectrometry.Anal Chem2006
16834341Comparative glycomics of the glycoprotein follicle stimulating hormone: glycopeptide analysis of isolates from two mammalian species.Biochemistry2006
15609366Differentiation between sulphated and phosphated carbohydrates in low-resolution matrix-assisted laser desorption/ionization mass spectra.Rapid Commun Mass Spectrom2005
15121204Glycoprotein profiling by electrospray mass spectrometry.J Am Soc Mass Spectrom2004
15311943Differential effects of alpha subunit Asparagine56 oligosaccharide structure on equine lutropin and follitropin hybrid conformation and receptor-binding activity.Biochemistry2004
12581881Inositol phosphate stimulation by LH requires the entire alpha Asn56 oligosaccharide.Mol Cell Endocrinol2003
11874703Truncated equine LH beta and asparagine(56)-deglycosylated equine LH alpha combine to produce a potent FSH antagonist.J Endocrinol2002
11133668Identification of twelve O-glycosylation sites in equine chorionic gonadotropin beta and equine luteinizing hormone ss by solid-phase Edman degradation.Biol Reprod2001
11502795Characterization of human FSH isoforms reveals a nonglycosylated beta-subunit in addition to the conventional glycosylated beta-subunit.J Clin Endocrinol Metab2001
10764604Carbohydrate analysis of glycoprotein hormones.Methods2000
9475402Hormone-specific inhibitory influence of alpha-subunit Asn56 oligosaccharide on in vitro subunit association and follicle-stimulating hormone receptor binding of equine gonadotropins.Biol Reprod1998
8641207Negative influence of O-linked oligosaccharides of high molecular weight equine chorionic gonadotropin on its luteinizing hormone and follicle-stimulating hormone receptor-binding activities.Endocrinology1996
9027339Structural features of mammalian gonadotropins.Mol Cell Endocrinol1996
8895101Circular dichroic spectroscopy of Arg46-nicked ovine lutropin alpha and derived fragments.J Protein Chem1996
8895086Glycosylated equine prolactin and its carbohydrate moiety.J Protein Chem1996
8641208Oligosaccharide mapping reveals hormone-specific glycosylation patterns on equine gonadotropin alpha-subunit Asn56.Endocrinology1996
7518386Evidence for two folding domains in glycoprotein hormone alpha-subunits.Endocrinology1994
  • 1 - 50 of 75

Recommended Authors

Shayli Varasteh Moradi
Queensland University of Technology
Career Start Year 2013
Number of shared co-authors 0
Chong-Feng Xu
Biogen Inc.
Career Start Year 2004
Number of shared co-authors 0
David J Ashline
University of New Hampshire
Career Start Year 2001
Number of shared co-authors 0
Fuming Zhang
Rensselaer Polytechnic Institute
Career Start Year 2000
Number of shared co-authors 0
Nan Leng
Xijing Hospital, The Fourth Military Medical University
Career Start Year 1995
Number of shared co-authors 0
Nicholas E Sherman
University of Virginia
Career Start Year 1994
Number of shared co-authors 0
Salvatore Sechi
National Institute of Diabetes and Digestive and Kidney Diseases
Career Start Year 1993
Number of shared co-authors 0
Charles E Lyons
Massey Cancer Center, Virginia Commonwealth University
Career Start Year 1992
Number of shared co-authors 0
Fu-Yue Zeng
Sanford Burnham Prebys Medical Discovery Institute
Career Start Year 1991
Number of shared co-authors 0
Lane K Christenson
University of Kansas Medical Center
Career Start Year 1991
Number of shared co-authors 2
Charles Pineau
French Institute of Health and Medical Research
Career Start Year 1988
Number of shared co-authors 0
Janet E Hall
2Clinical Research Branch, National Institute of Environmental Health Sciences
Career Start Year 1988
Number of shared co-authors 0
Fred C G J Sweep
Radboud University Medical Centre
Career Start Year 1987
Number of shared co-authors 0
Shiaw-Lin Wu
BioAnalytix Inc.
Career Start Year 1986
Number of shared co-authors 0
Eric P Smith
University of Cincinnati College of Medicine
Career Start Year 1986
Number of shared co-authors 0
Stanley R Krystek
Bristol-Myers Squibb Pharmaceutical Research Institute
Career Start Year 1985
Number of shared co-authors 0
Mark S Baker
Macquarie University
Career Start Year 1984
Number of shared co-authors 0
Stephen Fawell
Oncology R&D
Career Start Year 1984
Number of shared co-authors 0
Bradford W Gibson
The Buck Institute for Research on Aging
Career Start Year 1982
Number of shared co-authors 0
Robert J Linhardt
Rensselaer Polytechnic Institute
Career Start Year 1981
Number of shared co-authors 0
Yoshinao Wada
Osaka Women's and Children's Hospital
Career Start Year 1981
Number of shared co-authors 0
Jeffrey Shabanowitz
University of Virginia
Career Start Year 1980
Number of shared co-authors 0
Philip C Andrews
Sydney Children's Hospital, University of New South Wales
Career Start Year 1979
Number of shared co-authors 0
Catherine E Costello
Center for Biomedical Mass Spectrometry, Boston University
Career Start Year 1973
Number of shared co-authors 0
Edouard C Nice
Monash University
Career Start Year 1971
Number of shared co-authors 0
William S Hancock
Northeastern University
Career Start Year 1970
Number of shared co-authors 0
Donald F Hunt
University of Virginia
Career Start Year 1968
Number of shared co-authors 0
Vernon N Reinhold
College of Life Sciences and Agriculture, University of New Hampshire
Career Start Year 1968
Number of shared co-authors 0
Bert W O'Malley
Center for Coregulator Research, Baylor College of Medicine
Career Start Year 1964
Number of shared co-authors 0
Alma L Burlingame
Department of Pharmaceutical Chemistry, University of California san francisco
Career Start Year 1964
Number of shared co-authors 0

Collaborators

Aaron Smalter
Co-authored papers 3
Chittibabu Guda
Co-authored papers 3
Gerald H Lushington
Inc. 16 Dekalb Pike
Co-authored papers 2
Peter Humaidan
Co-authored papers 1
In-Hee Lee
Co-authored papers 1
Mahesh Visvanathan
University of Kansas
Co-authored papers 1
In-Hee Lee
Children's Hospital Boston
Co-authored papers 1
Mary C Farach-Carson
The University of Texas Health Science Center at Houston School of Dentistry
Co-authored papers 1
Sasidhar R Siddam
Co-authored papers 1
Release 1.2