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Author Details

Thomas Sparsø
2005
52
32
PMIDPaper TitleJournal TitlePublished Year
37693601Disruptive mutations in the serotonin transporter associate serotonin dysfunction with treatment-resistant affective disorder.2023
37590326BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus.PLoS Comput Biol2023
32895383Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission.Nat Commun2020
29886042Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study.Lancet Psychiatry2018
28114601Risk of Psychiatric Disorders Among Individuals With the 22q11.2 Deletion or Duplication: A Danish Nationwide, Register-Based Study.JAMA Psychiatry2017
28850114Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome.Translational Psychiatry2017
28566273An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Diabetes2017
28963451CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits.Nat Commun2017
27876822A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.Nat Commun2016
27355579Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.PLoS Genet2016
26390057Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.Nat Genet2015
25267602A glycogene mutation map for discovery of diseases of glycosylation.Glycobiology2015
25599387Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes.Journal of Clinical Endocrinology and Metabolism2015
26551672Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.Nat Genet2015
26426971The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.PLoS Genet2015
23804573The effect of GWAS identified BMI loci on changes in body weight among middle-aged Danes during a five-year period.2014
24448545Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population.European Journal of Human Genetics2014
23160641Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.Diabetologia2013
23754956Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets.PLoS Genet2013
24290377Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes.Am J Hum Genet2013
23835328Genetic risk score of 46 type 2 diabetes risk variants associates with changes in plasma glucose and estimates of pancreatic β-cell function over 5 years of follow-up.2013
23457408Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort.Journal of Clinical Endocrinology and Metabolism2013
22095239Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes.Diabetologia2012
22479202Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.PLoS Genet2012
22325233The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals.BMC Medical Genetics2012
23185617Genetic variant SLC2A2 [corrected] Is associated with risk of cardiovascular disease â¿¿ assessing the individual and cumulative effect of 46 type 2 diabetes related genetic variants.PLoS ONE2012
22238593A genome-wide association search for type 2 diabetes genes in African Americans.PLoS One2012
21249489The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals.Diabetologia2011
21267535Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release.Diabetologia2011
20581827Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.Nat Genet2010
20890277Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants.Nat Genet2010
20886378Physiologic characterization of type 2 diabetes-related loci.Current Diabetes Reports2010
20356931Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes.European Journal of Endocrinology2010
20081858New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.Nat Genet2010
20081857Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.Nat Genet2010
19933169Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes.Hum Mol Genet2010
20110568Combined analyses of 20 common obesity susceptibility variants.2010
20200315MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans.2010
19779622No consistent effect of ADRB2 haplotypes on obesity, hypertension and quantitative traits of body fatness and blood pressure among 6,514 adult Danes.PLoS ONE2009
19324940G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.2009
19404609Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction.Diabetologia2009
19060909A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.Nature Genetics2009
18316360AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects.2008
18008060The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.Diabetologia2008
18568334Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.Diabetologia2008
17129741Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people.Molecular Genetics and Metabolism2007
17327437Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites.Diabetes2007
17459095A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects.Diabetic Medicine2007
17681849Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites.Molecular Genetics and Metabolism2007
16755280Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes.International Journal of Obesity2007
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