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Author Details

Jean-Marie Dupret
Universite de Paris, CNRS
1986
105
31
PMIDPaper TitleJournal TitlePublished Year
34806245Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy.Protein Sci2022
35809481Cisplatin causes covalent inhibition of protein-tyrosine phosphatase 1B (PTP1B) through reaction with its active site cysteine: Molecular, cellular and in vivo mice studies.Biomed Pharmacother2022
35806064Biochemical, Enzymatic, and Computational Characterization of Recurrent Somatic Mutations of the Human Protein Tyrosine Phosphatase PTP1B in Primary Mediastinal B Cell Lymphoma.Int J Mol Sci2022
35806030Human Protein Tyrosine Phosphatase 1B (PTP1B): From Structure to Clinical Inhibitor Perspectives.Int J Mol Sci2022
33278510Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues.Free Radic Biol Med2021
34938157Carbon Black Nanoparticles Selectively Alter Follicle-Stimulating Hormone Expression <i>in vitro</i> and <i>in vivo</i> in Female Mice.Front Neurosci2021
34243013Etoposide, an anticancer drug involved in therapy-related secondary leukemia: Enzymes at play.Transl Oncol2021
34266924The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3).Mol Pharmacol2021
32089267From transglutaminases (TGs) to arylamine N-acetyltransferases (NATs): Insight into the role of a spatially conserved aromatic amino acid position in the active site of these two families of enzymes.Biochem Biophys Res Commun2020
30883722A readout of metabolic efficiency in arylamine N-acetyltransferase-deficient mice reveals minor energy metabolism changes.FEBS Lett2019
31667807The Structure and the Regulation of Glycogen Phosphorylases in Brain.Adv Neurobiol2019
31221825T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide.Mol Pharmacol2019
31248982Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling.J Biol Chem2019
27782369The structure of brain glycogen phosphorylase-from allosteric regulation mechanisms to clinical perspectives.FEBS J2017
28977593Carbon Black Nanoparticles Inhibit Aromatase Expression and Estradiol Secretion in Human Granulosa Cells Through the ERK1/2 Pathway.Endocrinology2017
28674152Human Arylamine <i>N</i>-Acetyltransferase 1 Is Inhibited by the Dithiocarbamate Pesticide Thiram.Mol Pharmacol2017
27846346Xenobiotic-metabolizing enzymes in Bacillus anthracis: molecular and functional analysis of a truncated arylamine N-acetyltransferase isozyme.Br J Pharmacol2017
27965358Molecular Mechanisms of Allosteric Inhibition of Brain Glycogen Phosphorylase by Neurotoxic Dithiocarbamate Chemicals.J Biol Chem2017
26840026Identification of cancer chemopreventive isothiocyanates as direct inhibitors of the arylamine N-acetyltransferase-dependent acetylation and bioactivation of aromatic amine carcinogens.Oncotarget2016
27660393An Isozyme-specific Redox Switch in Human Brain Glycogen Phosphorylase Modulates Its Allosteric Activation by AMP.J Biol Chem2016
27402852Insights into Brain Glycogen Metabolism: THE STRUCTURE OF HUMAN BRAIN GLYCOGEN PHOSPHORYLASE.J Biol Chem2016
25391334Effects of pesticide chemicals on the activity of metabolic enzymes: focus on thiocarbamates.Expert Opin Drug Metab Toxicol2015
26099937An acetyltransferase assay for CREB-binding protein based on reverse phase-ultra-fast liquid chromatography of fluorescent histone H3 peptides.Anal Biochem2015
26040922A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2).Sci Rep2015
26068093Screen for soil fungi highly resistant to dichloroaniline uncovers mostly Fusarium species.Fungal Genet Biol2015
25664736Insight into cofactor recognition in arylamine N-acetyltransferase enzymes: structure of Mesorhizobium loti arylamine N-acetyltransferase in complex with coenzyme A.Acta Crystallogr D Biol Crystallogr2015
25224404Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites.Arch Toxicol2015
24269889Skeletal muscle glycogen phosphorylase is irreversibly inhibited by mercury: molecular, cellular and kinetic aspects.FEBS Lett2014
25372695Structural and functional characterization of an arylamine N-acetyltransferase from the pathogen Mycobacterium abscessus: differences from other mycobacterial isoforms and implications for selective inhibition.Acta Crystallogr D Biol Crystallogr2014
24823794From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2.PLoS One2014
24683030Intracellular signal modulation by nanomaterials.Adv Exp Med Biol2014
24374000A high-performance liquid chromatography assay for Dyrk1a, a Down syndrome-associated kinase.Anal Biochem2014
24328723Arylamine N-acetyltransferases: a structural perspective. Comments regarding the BJP paper by Zhou et al., 2013.Br J Pharmacol2014
23289949Crystal structure of arylamine N-acetyltransferases: insights into the mechanisms of action and substrate selectivity.Expert Opin Drug Metab Toxicol2013
23940600A novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1.PLoS One2013
23633528Acrolein, an α,β-unsaturated aldehyde, irreversibly inhibits the acetylation of aromatic amine xenobiotics by human arylamine N-acetyltransferase 1.Drug Metab Dispos2013
23770703Structural and biochemical characterization of an active arylamine N-acetyltransferase possessing a non-canonical Cys-His-Glu catalytic triad.J Biol Chem2013
23728813Biotransformation of Trichoderma spp. and their tolerance to aromatic amines, a major class of pollutants.Appl Environ Microbiol2013
22297998Purification, crystallization and preliminary X-ray characterization of Bacillus cereus arylamine N-acetyltransferase 3 [(BACCR)NAT3].Acta Crystallogr Sect F Struct Biol Cryst Commun2012
22545684Characterization of an acetyltransferase that detoxifies aromatic chemicals in Legionella pneumophila.Biochem J2012
21499321Fungi as a promising tool for bioremediation of soils contaminated with aromatic amines, a major class of pollutants.Nat Rev Microbiol2011
22062153The Bacillus anthracis arylamine N-acetyltransferase ((BACAN)NAT1) that inactivates sulfamethoxazole, reveals unusual structural features compared with the other NAT isoenzymes.FEBS Lett2011
21843062Pharmacogenomics, biochemistry, toxicology, microbiology and cancer research in one go.Pharmacogenomics2011
21526848Carbon black nanoparticles impair acetylation of aromatic amine carcinogens through inactivation of arylamine N-acetyltransferase enzymes.ACS Nano2011
21550378Effect of red wine polyphenol dietary supplementation on two phase II enzymes in liver of hyperhomocysteinemic mice.Food Chem Toxicol2011
20041842Human arylamine N-acetyltransferase 1: a drug-metabolizing enzyme and a drug target?Curr Drug Targets2010
20810355Cadmium alters the biotransformation of carcinogenic aromatic amines by arylamine N-acetyltransferase xenobiotic-metabolizing enzymes: molecular, cellular, and in vivo studies.Environ Health Perspect2010
20591428The human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) is irreversibly inhibited by inorganic (Hg2+) and organic mercury (CH3Hg+): mechanism and kinetics.FEBS Lett2010
20676885Insights into the phylogeny or arylamine N-acetyltransferases in fungi.J Mol Evol2010
19248797Arylamine N-acetyltransferase activity in bronchial epithelial cells and its inhibition by cellular oxidants.Toxicol Appl Pharmacol2009
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Collaborators

Universite Paris Cite, CNRS
Co-authored papers 76
INSERM UMR-S1124, Universite Paris Cite
Co-authored papers 19
Universite Paris Cite, CNRS
Co-authored papers 16
University of Toronto
Co-authored papers 9
Shandong Jianzhu University
Co-authored papers 7
PSL Universite, CNRS
Co-authored papers 4
Universite PSL, LPC CNRS UMR8249
Co-authored papers 4
University Claude Bernard Lyon 1
Co-authored papers 3
Universite Paris Cite, CNRS
Co-authored papers 2
University of Lorraine
Co-authored papers 1
Institut Francois Jacob, CNRS, Universite Paris-Saclay
Co-authored papers 1
Co-authored papers 1
Departments of Pharmaceutical Sciences.
Co-authored papers 1
European Hospital Georges Pompidou, University of Paris Descartes
Co-authored papers 1
University of California los angeles
Co-authored papers 1
Universite de Paris, CNRS
Co-authored papers 1
Universite de Paris, CNRS
Co-authored papers 1
Universite de Paris, CNRS
Co-authored papers 1
University Health Network
Co-authored papers 1
University of Toronto
Co-authored papers 1