Author details

Full Name

Hua Cai

Affiliation

ORCID

Career Start Year

1998

Papers

118

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37186669	Restoration of coronary microvascular function by OGA overexpression in a high-fat diet with low-dose streptozotocin-induced type 2 diabetic mice.		2023
37018969	Endothelial damage in young adult e-cigarette users.		2023
37377116	Sirtuin 2 deficiency aggravates ageing-induced vascular remodelling in humans and mice.		2023
35167418	eNAMPT Is a Novel Damage-associated Molecular Pattern Protein That Contributes to the Severity of Radiation-induced Lung Fibrosis.	Am J Respir Cell Mol Biol	2022
36307318	Corrigendum to "Diagnostic and predictive values of circulating tetrahydrobiopterin levels as a novel biomarker in patients with thoracic and abdominal aortic aneurysms" [Redox Biol. 56 (2022) 102444].	Redox Biol	2022
36179995	TLR4 activation induces inflammatory vascular permeability via Dock1 targeting and NOX4 upregulation.		2022
35651727	Reversal of NADPH Oxidase-Dependent Early Oxidative and Inflammatory Responses in Chronic Obstructive Pulmonary Disease by Puerarin.	Oxidative Medicine and Cellular Longevity	2022
35830752	Novel and robust treatment of pulmonary hypertension with netrin-1 and netrin-1-derived small peptides.	Redox Biology	2022
36009258	NADPH Oxidase Isoforms in COPD Patients and Acute Cigarette Smoke-Exposed Mice: Induction of Oxidative Stress and Lung Inflammation.	Antioxidants	2022
35812318	eNAMPT Neutralization Preserves Lung Fluid Balance and Reduces Acute Renal Injury in Porcine Sepsis/VILI-Induced Inflammatory Lung Injury.	Frontiers in Physiology	2022
36277223	Editorial: Osteoporosis, sarcopenia and muscle-bone crosstalk in COPD.	Frontiers in Physiology	2022
35624768	Flavored and Nicotine-Containing E-Cigarettes Induce Impaired Angiogenesis and Diabetic Wound Healing via Increased Endothelial Oxidative Stress and Reduced NO Bioavailability.	Antioxidants	2022
36459715	Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication.	Redox Biology	2022
34844898	Erratum to Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction, Redox Biology 36 (2020) 101638.	Redox Biology	2021
33811957	Traditional Chinese Medicine (TCM) in the treatment of COVID-19 and other viral infections: Efficacies and mechanisms.	Pharmacology and Therapeutics	2021
34176283	Targeting MicroRNA-192-5p, a Downstream Effector of NOXs (NADPH Oxidases), Reverses Endothelial DHFR (Dihydrofolate Reductase) Deficiency to Attenuate Abdominal Aortic Aneurysm Formation.	Hypertension	2021
34127487	Toll-Like Receptor 2 (TLR2) Knockout Abrogates Diabetic and Obese Phenotypes While Restoring Endothelial Function via Inhibition of NOX1.		2021
34025456	More to Explore: Further Definition of Risk Factors for COPD - Differential Gender Difference, Modest Elevation in PM., and e-Cigarette Use.	Frontiers in Physiology	2021
33126053	Targeting feed-forward signaling of TGFÎ²/NOX4/DHFR/eNOS uncoupling/TGFÎ² axis with anti-TGFÎ² and folic acid attenuates formation of aortic aneurysms: Novel mechanisms and therapeutics.	Redox Biology	2021
34509916	Therapeutic application of estrogen for COVID-19: Attenuation of SARS-CoV-2 spike protein and IL-6 stimulated, ACE2-dependent NOX2 activation, ROS production and MCP-1 upregulation in endothelial cells.	Redox Biology	2021
34805919	Expert consensus on interventional therapy for traumatic splenic bleeding.	Journal of Interventional Medicine	2020
31591535	NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets.	Nature Reviews Cardiology	2020
32252929	More to Add to E-Cigarette Regulations: Unified Approaches.	Chest	2020
32171067	Sex difference and smoking predisposition in patients with COVID-19.	Lancet Respiratory Medicine,The	2020
31922237	Metformin attenuates the Dâ¿¿galactoseâ¿¿induced aging process via the UPR through the AMPK/ERK1/2 signaling pathways.	International Journal of Molecular Medicine	2020
32863203	Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction.	Redox Biology	2020
30954686	Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction.	Redox Biology	2019
30571557	Novel Treatment of Hypertension by Specifically Targeting E2F for Restoration of Endothelial Dihydrofolate Reductase and eNOS Function Under Oxidative Stress.	Hypertension	2019
31232964	Association of polymorphisms in grainyhead-like-2 gene with the susceptibility to age-related hearing loss: A systematic review and meta-analysis.	Medicine (United States)	2019
29844188	KDM4B protects against obesity and metabolic dysfunction.	Proc Natl Acad Sci U S A	2018
30272261	Age-associated decline in Nrf2 signaling and associated mtDNA damage may be involved in the degeneration of the auditory cortex: Implications for central presbycusis.	International Journal of Molecular Medicine	2018
27912196	NOX isoforms in the development of abdominal aortic aneurysm.	Redox Biology	2017
28694198	Surviving With Smog and Smoke: Precision Interventions?	Chest	2017
28499253	The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKÎ²/AMPK pathways.	Redox Biology	2017
28583438	Editorial commentary: Endothelial-to-mesenchymal transition: When the good one goes bad.	Trends in Cardiovascular Medicine	2017
28667909	Graphical review: The redox dark side of e-cigarettes; exposure to oxidants and public health concerns.	Redox Biology	2017
28366876	Endothelial cell calpain as a critical modulator of angiogenesis.	Biochimica et Biophysica Acta - Molecular Basis of Disease	2017
29038536	Hydrogen Sulphide Treatment Increases Insulin Sensitivity and Improves Oxidant Metabolism through the CaMKKbeta-AMPK Pathway in PA-Induced IR C2C12 Cells.	Scientific Reports	2017
28004124	Attenuation of neointimal formation with netrin-1 and netrin-1 preconditioned endothelial progenitor cells.	Journal of Molecular Medicine	2017
27872190	Protein Phosphotyrosine Phosphatase 1B (PTP1B) in Calpain-dependent Feedback Regulation of Vascular Endothelial Growth Factor Receptor (VEGFR2) in Endothelial Cells: IMPLICATIONS IN VEGF-DEPENDENT ANGIOGENESIS AND DIABETIC WOUND HEALING.	Journal of Biological Chemistry	2017
26595812	Immune activation caused by vascular oxidation promotes fibrosis and hypertension.	Journal of Clinical Investigation	2016
27059949	Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure.	Circulation	2016
26826128	Differential Roles of Protein Complexes NOX1-NOXO1 and NOX2-p47phox in Mediating Endothelial Redox Responses to Oscillatory and Unidirectional Laminar Shear Stress.	Journal of Biological Chemistry	2016
27035819	Immune activation caused by vascular oxidation promotes fibrosis and hypertension.	Journal of Clinical Investigation	2016
25066694	Netrin-1 abrogates ischemia/reperfusion-induced cardiac mitochondrial dysfunction via nitric oxide-dependent attenuation of NOX4 activation and recoupling of NOS.	J Mol Cell Cardiol	2015
25924621	Induction of cardioprotection by small netrin-1-derived peptides.	American Journal of Physiology - Cell Physiology	2015
25882860	Mechanisms and consequences of endothelial nitric oxide synthase dysfunction in hypertension.	Journal of Hypertension	2015
25794433	Fueling up skeletal muscle to reduce obesity: A TrkB story.		2015
25817885	ANO1 taking center stage: blood pressure regulation in SHRs.	Journal of Molecular and Cellular Cardiology	2015
25561546	Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1/NO.	Proceedings of the National Academy of Sciences of the United States of America	2015