Author details

Full Name

Paul Zumbo

Affiliation

ORCID

Career Start Year

2009

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37537361	Hallmarks of CD8 T cell dysfunction are established within hours of tumor antigen encounter before cell division.		2023
36322790	Increased Primary Bile Acids with Ileocolonic Resection Impact Ileal Inflammation and Gut Microbiota in Inflammatory Bowel Disease.	J Crohns Colitis	2023
37581929	The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells.	JCI Insight	2023
38056453	A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas.	Dev Cell	2023
37461721	Intratumoral immune triads are required for adoptive T cell therapy-mediated elimination of solid tumors.	bioRxiv	2023
36868194	hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease.	Cell Stem Cell	2023
36993713	Cross-species single-cell comparison of systemic and cardiac inflammatory responses after cardiac injury.		2023
37046694	TCF12 Deficiency Impairs the Proliferation of Glioblastoma Tumor Cells and Improves Survival.		2023
36928765	A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes.		2023
36853799	Epsilon toxin-producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege.	J Clin Invest	2023
36599003	Activation of MAP2K signaling by genetic engineering or HF-rTMS promotes corticospinal axon sprouting and functional regeneration.	Sci Transl Med	2023
34935874	TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion.	J Exp Med	2022
35484264	Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.	Nat Med	2022
35985993	SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8<sup>+</sup> T-cells.	Nat Commun	2022
36513650	Activation of a transient progenitor state in the epicardium is required for zebrafish heart regeneration.		2022
34847567	An autoimmune stem-like CD8 T cell population drives type 1 diabetes.	Nature	2022
34354664	Hippocampal Transcriptome Changes After Subarachnoid Hemorrhage in Mice.	Frontiers in Neurology	2021
33941818	Pleckstrin-2 is essential for erythropoiesis in Î²-thalassemic mice, reducing apoptosis and enhancing enucleation.	Commun Biol	2021
33558694	Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer's disease.	Nat Neurosci	2021
33980597	Selective BCL-X<sub>L</sub> Antagonists Eliminate Infected Cells from a Primary-Cell Model of HIV Latency but Not from <i>Ex Vivo</i> Reservoirs.	J Virol	2021
31520587	A comprehensive, multidisciplinary, precision medicine approach to discover effective therapy for an undiagnosed, progressive, fibroinflammatory disease.	Transl Res	2020
32908310	Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis.	Nature	2020
32560455	A Novel JAK1 Mutant Breast Implant-Associated Anaplastic Large Cell Lymphoma Patient-Derived Xenograft Fostering Pre-Clinical Discoveries.	Cancers (Basel)	2020
32667883	Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531.	Elife	2020
31110351	Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation.	Nat Genet	2019
31207604	TOX is a critical regulator of tumour-specific T cell differentiation.	Nature	2019
26980833	Features of Circulating Parainfluenza Virus Required for Growth in Human Airway.	mBio	2016
26594662	Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics.	Cell Syst	2015
27135684	Modern Methods for Delineating Metagenomic Complexity.	Cell Syst	2015
27135689	Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics.	Cell Syst	2015
26361796	Mining the Archives: A Cross-Platform Analysis of Gene Expression Profiles in Archival Formalin-Fixed Paraffin-Embedded Tissues.	Toxicol Sci	2015
26597945	Erratum to: Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data.	Genome Biol	2015
25150835	Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study.	Nat Biotechnol	2014
25150837	Detecting and correcting systematic variation in large-scale RNA sequencing data.	Nat Biotechnol	2014
23735126	An optimized algorithm for detecting and annotating regional differential methylation.	BMC Bioinformatics	2013
23911289	A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.	Cell Rep	2013
24020486	Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data.	Genome Biol	2013
23377183	Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia.	Nat Genet	2013
23203872	The non-human primate reference transcriptome resource (NHPRTR) for comparative functional genomics.	Nucleic Acids Res	2013
22608085	Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons.	Cell	2012
20009012	Sex-specific and lineage-specific alternative splicing in primates.	Genome Res	2010
20865556	Standardizing the next generation of bioinformatics software development with BioHDF (HDF5).	Adv Exp Med Biol	2010
19861545	Genetic diagnosis by whole exome capture and massively parallel DNA sequencing.	Proc Natl Acad Sci U S A	2009