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Author Details

Andrew P May
Fluidigm Corporation
1997
41
26
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36706756An ependymal cell census identifies heterogeneous and ongoing cell maturation in the adult mouse spinal cord that changes dynamically on injury.Dev Cell2023
35365639A functional map of HIV-host interactions in primary human T cells.Nat Commun2022
34478654Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells.Mol Cell2021
32995354Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors.Mol Ther Methods Clin Dev2020
31359007Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.Nat Biotechnol2019
31659048Nucleic acid cleavage with a hyperthermophilic Cas9 from an uncultured Ignavibacterium.Proc Natl Acad Sci U S A2019
31740839Harnessing type I CRISPR-Cas systems for genome engineering in human cells.Nat Biotechnol2019
31855083Fast-Seq: A Simple Method for Rapid and Inexpensive Validation of Packaged Single-Stranded Adeno-Associated Viral Genomes in Academic Settings.Hum Gene Ther Methods2019
28778606Advances in Industrial Biotechnology Using CRISPR-Cas Systems.Trends Biotechnol2018
29995861Reprogramming human T cell function and specificity with non-viral genome targeting.Nature2018
28459459Mapping the genomic landscape of CRISPR-Cas9 cleavage.Nat Methods2017
27499295DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks.Mol Cell2016
25535790Unraveling the potential of CRISPR-Cas9 for gene therapy.Expert Opin Biol Ther2015
24166983Clinical and pathological impact of VHL, PBRM1, BAP1, SETD2, KDM6A, and JARID1c in clear cell renal cell carcinoma.Genes Chromosomes Cancer2014
25373540Guide RNA functional modules direct Cas9 activity and orthogonality.Mol Cell2014
25086649Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex.Nat Biotechnol2014
24952744Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis.Nat Genet2014
24919153Single-cell RNA-seq reveals dynamic paracrine control of cellular variation.Nature2014
23398507High throughput HLA genotyping using 454 sequencing and the Fluidigm Access Arrayâ¿¢ System for simplified amplicon library preparation.Tissue Antigens2013
22393408Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization.PLoS One2012
23063122A structural basis for the assembly and functions of a viral polymer that inactivates multiple tumor suppressors.Cell2012
22649089Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA.Sci Transl Med2012
21061422The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication.Wiley Interdiscip Rev Syst Biol Med2011
20675723A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function.Nucleic Acids Res2010
18542878Efficient macromolecular crystallization using microfluidics and randomized design of screening reagents.Methods Mol Biol2008
17137591Crystallographic and in silico analysis of the sialoside-binding characteristics of the Siglec sialoadhesin.J Mol Biol2007
15807526Crystal structure and mechanism of the Escherichia coli ArnA (PmrI) transformylase domain. An enzyme for lipid A modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance.Biochemistry2005
15939024Structure and mechanism of ArnA: conformational change implies ordered dehydrogenase mechanism in key enzyme for polymyxin resistance.Structure2005
15698563Conformational changes of p97 during nucleotide hydrolysis determined by small-angle X-Ray scattering.Structure2005
15491143Crystal structure of Escherichia coli ArnA (PmrI) decarboxylase domain. A key enzyme for lipid A modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance.Biochemistry2004
11781091Uncoupling the ATPase activity of the N-ethylmaleimide sensitive factor (NSF) from 20S complex disassembly.Biochemistry2002
12434150Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle.Nat Struct Biol2002
11190672Sialoadhesin structure.Results Probl Cell Differ2001
11301340Unraveling the mechanism of the vesicle transport ATPase NSF, the N-ethylmaleimide-sensitive factor.J Biol Chem2001
11533035Crystal structure and biophysical properties of a complex between the N-terminal SNARE region of SNAP25 and syntaxin 1a.J Biol Chem2001
11114503Protein-protein interactions in intracellular membrane fusion.Curr Opin Struct Biol2000
10559905Crystal structure of the amino-terminal domain of N-ethylmaleimide-sensitive fusion protein.Nat Cell Biol1999
10087915Integrin alpha- and beta 4-subunit-domain homologues in cyanobacterial proteins.Trends Biochem Sci1999
9686599The leukocyte function-associated antigen-1 (LFA-1)-binding site on ICAM-3 comprises residues on both faces of the first immunoglobulin domain.J Immunol1998
9660955Crystal structure of the N-terminal domain of sialoadhesin in complex with 3' sialyllactose at 1.85 A resolution.Mol Cell1998
9070454Expression, crystallization, and preliminary X-ray analysis of a sialic acid-binding fragment of sialoadhesin in the presence and absence of ligand.Protein Sci1997
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Collaborators

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Co-authored papers 3
Fred Hutchinson Cancer Center
Co-authored papers 3
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Co-authored papers 3
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Co-authored papers 3
Innovative Genomics Institute, University of California berkeley
Co-authored papers 3
North Carolina State University
Co-authored papers 3
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 2
University of California, USA Howard Hughes Medical Institute san francisco
Co-authored papers 2
Northwestern University Feinberg School of Medicine
Co-authored papers 2
California Institute of Technology
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
The University of Edinburgh
Co-authored papers 2
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University of California san francisco
Co-authored papers 1
Co-authored papers 1
Stanford University
Co-authored papers 1
Co-authored papers 1
Gladstone Institutes
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Irving Institute for Cancer Dynamics, Columbia University
Co-authored papers 1
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 1
The Medical School, The University of Sheffield
Co-authored papers 1
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Center for Computational Biology, University of California berkeley
Co-authored papers 1
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Center for Genomics and Systems Biology, New York University
Co-authored papers 1
Stanford University
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Cambridge University Hospitals National Health Service Foundation Trust
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