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Author Details
Full Name
R S Hansen
Affiliation
University of Washington
ORCID
Career Start Year
1982
Papers
57
H Index
38
Expertise
CM4AI Collaborator
Nathan Sheffield (CM4AI)
PMID
Paper Title
Journal Title
Published Year
25693563
Integrative analysis of 111 reference human epigenomes.
Nature
2015
25972927
DNase I hypersensitivity analysis of the mouse brain and retina identifies region-specific regulatory elements.
Epigenetics Chromatin
2015
25282150
A genome-wide map of adeno-associated virus-mediated human gene targeting.
Nat Struct Mol Biol
2014
25411453
Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution.
Science
2014
25409831
Topologically associating domains are stable units of replication-timing regulation.
Nature
2014
25409824
A comparative encyclopedia of DNA elements in the mouse genome.
Nature
2014
25409825
Conservation of trans-acting circuitry during mammalian regulatory evolution.
Nature
2014
22955617
The accessible chromatin landscape of the human genome.
Nature
2012
22955828
Systematic localization of common disease-associated variation in regulatory DNA.
Science
2012
22955618
An expansive human regulatory lexicon encoded in transcription factor footprints.
Nature
2012
21258320
Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site.
Nature
2011
21791604
Analysis of human syndromes with disordered chromatin reveals the impact of heterochromatin on the efficacy of ATM-dependent G2/M checkpoint arrest.
Mol Cell Biol
2011
21957152
Late-replicating heterochromatin is characterized by decreased cytosine methylation in the human genome.
Genome Res
2011
19966280
Sequencing newly replicated DNA reveals widespread plasticity in human replication timing.
Proc Natl Acad Sci U S A
2010
19997486
Dosage regulation of the active X chromosome in human triploid cells.
PLoS Genet
2009
17921506
An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals.
Hum Mol Genet
2007
17955361
Encoding PCR products with batch-stamps and barcodes.
Biochem Genet
2007
16426903
Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity.
DNA Repair (Amst)
2006
16817970
Abnormal X: autosome ratio, but normal X chromosome inactivation in human triploid cultures.
BMC Genet
2006
16500999
Maintenance of X- and Y-inactivation of the pseudoautosomal (PAR2) gene SPRY3 is independent from DNA methylation and associated to multiple layers of epigenetic modifications.
Hum Mol Genet
2006
15710616
Hemimethylation and non-CpG methylation levels in a promoter region of human LINE-1 (L1) repeated elements.
J Biol Chem
2005
14673087
Hairpin-bisulfite PCR: assessing epigenetic methylation patterns on complementary strands of individual DNA molecules.
Proc Natl Acad Sci U S A
2004
15377381
Normal histone modifications on the inactive X chromosome in ICF and Rett syndrome cells: implications for methyl-CpG binding proteins.
BMC Biol
2004
15459281
Molecular barcodes detect redundancy and contamination in hairpin-bisulfite PCR.
Nucleic Acids Res
2004
12925568
X inactivation-specific methylation of LINE-1 elements by DNMT3B: implications for the Lyon repeat hypothesis.
Hum Mol Genet
2003
12444103
Allelic inactivation of the pseudoautosomal gene SYBL1 is controlled by epigenetic mechanisms common to the X and Y chromosomes.
Hum Mol Genet
2002
12900541
ICF syndrome cells as a model system for studying X chromosome inactivation.
Cytogenet Genome Res
2002
12411943
A new regulatory pathway for fragile X syndrome?
Nat Med
2002
11702227
Satellite 2 methylation patterns in normal and ICF syndrome cells and association of hypomethylation with advanced replication.
Hum Genet
2001
11063717
Escape from gene silencing in ICF syndrome: evidence for advanced replication time as a major determinant.
Hum Mol Genet
2000
11102980
Genetic variation in ICF syndrome: evidence for genetic heterogeneity.
Hum Mutat
2000
11196131
Analysis of replication timing at the FRA10B and FRA16B fragile site loci.
Chromosome Res
2000
10588719
The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome.
Proc Natl Acad Sci U S A
1999
10332041
The timing of XIST replication: dominance of the domain.
Hum Mol Genet
1999
9892682
DNA methylation in transcriptional repression of two differentially expressed X-linked genes, GPC3 and SYBL1.
Proc Natl Acad Sci U S A
1999
9736721
Very late DNA replication in the human cell cycle.
Proc Natl Acad Sci U S A
1998
9560241
Reactivation of XIST in normal fibroblasts and a somatic cell hybrid: abnormal localization of XIST RNA in hybrid cells.
Proc Natl Acad Sci U S A
1998
9114034
A variable domain of delayed replication in FRAXA fragile X chromosomes: X inactivation-like spread of late replication.
Proc Natl Acad Sci U S A
1997
9169463
5-Azadeoxycytidine-induced chromatin remodeling of the inactive X-linked HPRT gene promoter occurs prior to transcription factor binding and gene reactivation.
J Biol Chem
1997
8872476
Role of late replication timing in the silencing of X-linked genes.
Hum Mol Genet
1996
7633440
Reverse replication timing for the XIST gene in human fibroblasts.
Hum Mol Genet
1995
8634700
Allele-specific replication timing in imprinted domains: absence of asynchrony at several loci.
Hum Mol Genet
1995
7956079
Chromosomal fragile sites: molecular test of the delayed-replication model.
Cold Spring Harb Symp Quant Biol
1993
8324827
Association of fragile X syndrome with delayed replication of the FMR1 gene.
Cell
1993
1301165
Methylation analysis of CGG sites in the CpG island of the human FMR1 gene.
Hum Mol Genet
1992
1380647
Hemimethylation and hypersensitivity are early events in transcriptional reactivation of human inactive X-linked genes in a hamster x human somatic cell hybrid.
Mol Cell Biol
1992
1693431
5-Azacytidine-induced reactivation of the human X chromosome-linked PGK1 gene is associated with a large region of cytosine demethylation in the 5' CpG island.
Proc Natl Acad Sci U S A
1990
2236038
Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability.
Proc Natl Acad Sci U S A
1990
2842618
Purification of calmodulin-stimulated cyclic nucleotide phosphodiesterase by monoclonal antibody affinity chromatography.
Methods Enzymol
1988
2850467
Demethylation of specific sites in the 5' region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression.
Mol Cell Biol
1988
1 - 50 of 57
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