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Author Details

Faiyaz Notta
2Ontario Institute for Cancer Research
2009
60
29
PMIDPaper TitleJournal TitlePublished Year
34583947Molecular characterisation of pancreatic ductal adenocarcinoma with <i>NTRK</i> fusions and review of the literature.J Clin Pathol2023
37525960hENT1 as a Predictive Biomarker in PDAC-Response.Clin Cancer Res2023
37856226Machine Learning-Based Early Warning Systems for Acute Care Utilization During Systemic Therapy for Cancer.J Natl Compr Canc Netw2023
37449843Spectrum of Response to Platinum and PARP Inhibitors in Germline BRCA-Associated Pancreatic Cancer in the Clinical and Preclinical Setting.Cancer Discov2023
37337105Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia.Nat Genet2023
37134154Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases.Sci Transl Med2023
37131797p73 activates transcriptional signatures of basal lineage identity and ciliogenesis in pancreatic ductal adenocarcinoma.bioRxiv2023
36915452Whole-genome sequencing of 20 cholangiocarcinoma cases reveals unique profiles in patients with cirrhosis and primary sclerosing cholangitis.J Gastrointest Oncol2023
36907523A TEAD2-Driven Endothelial-Like Program Shapes Basal-Like Differentiation and Metastasis of Pancreatic Cancer.Gastroenterology2023
36927977Systemic inflammatory prognostic scores in advanced pancreatic adenocarcinoma.Br J Cancer2023
34551968<i>MYC</i> Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma.Cancer Discov2022
35694787Correction: GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer.Clin Cancer Res2022
36591282Metastatic phenotype and immunosuppressive tumour microenvironment in pancreatic ductal adenocarcinoma: Key role of the urokinase plasminogen activator (PLAU).Front Immunol2022
36417526Widespread hypertranscription in aggressive human cancers.Sci Adv2022
36209277Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma.Nat Commun2022
36131042A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome.Leukemia2022
36223343Mitochondrial fitness and cancer risk.PLoS One2022
36222851hENT1 Expression Predicts Response to Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Ductal Adenocarcinoma.Clin Cancer Res2022
35978189Ordered and deterministic cancer genome evolution after p53 loss.Nature2022
36344707MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis.Nat Cancer2022
32958704Delving into Early-onset Pancreatic Ductal Adenocarcinoma: How Does Age Fit In?Clin Cancer Res2021
33589425PTHrP Drives Pancreatic Cancer Growth and Metastasis and Reveals a New Therapeutic Vulnerability.Cancer Discov2021
33524400Genomic Features and Classification of Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma.Gastroenterology2021
35121902APOBEC3A drives deaminase domain-independent chromosomal instability to promote pancreatic cancer metastasis.Nat Cancer2021
34644529Spatially confined sub-tumor microenvironments in pancreatic cancer.Cell2021
34757307Genomic sequencing to inform therapy in advanced pancreatic cancer: A systematic review and meta-analysis of prospective studies.Cancer Treat Rev2021
33962950NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4.Sci Adv2021
34294813The value of GATA6 immunohistochemistry and computer-assisted diagnosis to predict clinical outcome in advanced pancreatic cancer.Sci Rep2021
33051307Subtype-Discordant Pancreatic Ductal Adenocarcinoma Tumors Show Intermediate Clinical and Molecular Characteristics.Clin Cancer Res2021
32933947Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma.Gut2021
31481506Altered Gene Expression along the Glycolysis-Cholesterol Synthesis Axis Is Associated with Outcome in Pancreatic Cancer.Clin Cancer Res2020
31964786A Four-Chemokine Signature Is Associated with a T-cell-Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer.Clin Cancer Res2020
31932696Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution.Nat Genet2020
32051610Author Correction: Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution.Nat Genet2020
32703770Intraductal Transplantation Models of Human Pancreatic Ductal Adenocarcinoma Reveal Progressive Transition of Molecular Subtypes.Cancer Discov2020
32156747GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer.Clin Cancer Res2020
31435024Cryptic genomic lesions in adverse-risk acute myeloid leukemia identified by integrated whole genome and transcriptome sequencing.Leukemia2020
31201285Morphological classification of pancreatic ductal adenocarcinoma that predicts molecular subtypes and correlates with clinical outcome.Gut2020
30686769Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases.Cancer Cell2019
29288237Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial.Clin Cancer Res2018
29853643Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.Cancer Discov2018
29378198Mutations in Mitochondrial DNA From Pancreatic Ductal Adenocarcinomas Associate With Survival Times of Patients and Accumulate as Tumors Progress.Gastroenterology2018
27678171Senescent Carcinoma-Associated Fibroblasts Upregulate IL8 to Enhance Prometastatic Phenotypes.Mol Cancer Res2017
28993418A genetic roadmap of pancreatic cancer: still evolving.Gut2017
27851734Erratum: A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.Nature2017
27768182Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma.JAMA Oncol2017
27732578A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.Nature2016
26541609Distinct routes of lineage development reshape the human blood hierarchy across ontogeny.Science2016
24791856Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts.Leukemia2015
26321221Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.Cancer Cell2015
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Collaborators

Steven Gallinger
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto
Co-authored papers 35
Gun Ho Jang
Ontario Institute for Cancer Research
Co-authored papers 28
Robert E Denroche
Ontario Institute for Cancer Research
Co-authored papers 24
Julie M Wilson
Ontario Institute for Cancer Research
Co-authored papers 24
John E Dick
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 17
John M S Bartlett
University of Edinburgh
Co-authored papers 10
Dianne Chadwick
University Health Network
Co-authored papers 9
Michelle Chan-Seng-Yue
Princess Margaret Cancer Centre
Co-authored papers 9
Ashton A Connor
Houston Methodist Hospital
Co-authored papers 9
John D McPherson
Ontario Institute for Cancer Research
Co-authored papers 7
Paul M Krzyzanowski
Ontario Institute for Cancer Research
Co-authored papers 7
Sergei Doulatov
University of Washington
Co-authored papers 7
Steven J M Jones
University of British Columbia
Co-authored papers 6
Janessa Laskin
Co-authored papers 6
Lincoln Stein
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 6
Marco A Marra
University of British Columbia
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Charles G Mullighan
St Jude Children's Research Hospital
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Rama Khokha
Princess Margaret Cancer Centre, University Health Network
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Kolja Eppert
McGill University
Co-authored papers 4
David W Hedley
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Gloria M Petersen
Mayo Clinic
Co-authored papers 4
Andrew J Mungall
Co-authored papers 4
Mathieu Lemire
The Hospital for Sick Children
Co-authored papers 4
Lee Timms
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 4
Richard A Moore
Co-authored papers 4
Peter J Campbell
Wellcome Sanger Institute
Co-authored papers 4
Steve E Kalloger
University of British Columbia
Co-authored papers 4
Andrew M K Brown
Ontario Institute for Cancer Research
Co-authored papers 4
Francisco X Real
Spanish National Cancer Research Centre-CNIO
Co-authored papers 3
Ludmil B Alexandrov
Moores Cancer Center, university of california san diego
Co-authored papers 3
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