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Author Details

Xia Shen
Usher Institute, University of Edinburgh
2011
52
19
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36824751Genetic mechanisms of 184 neuro-related proteins in human plasma.medRxiv2023
37325708Hidden Genetic Regulation of Human Complex Traits via Brain Isoforms.Phenomics2023
37304119Two-sample Mendelian randomization analysis evaluates causal associations between inflammatory bowel disease and osteoporosis.Front Public Health2023
37034613Unraveling Neuro-Proteogenomic Landscape and Therapeutic Implications for Human Behaviors and Psychiatric Disorders.Res Sq2023
36918541Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.Nat Commun2023
36842216Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases.EBioMedicine2023
35003892SARS-CoV-2 causes a significant stress response mediated by small RNAs in the blood of COVID-19 patients.Mol Ther Nucleic Acids2022
35444688Integration of Distinct Analysis Strategies Improves Tissue-Trait Association Identification.Front Genet2022
35387486Genetic Landscape of the ACE2 Coronavirus Receptor.Circulation2022
35357430Genetic and phenotypic links between obesity and extracellular vesicles.Hum Mol Genet2022
36395956Integrative analysis of multiomics data identifies selenium-related gene ALAD associating with keshan disease.Free Radic Biol Med2022
36266475Contribution of CRISPRable DNA to human complex traits.Commun Biol2022
36050321Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.Nat Commun2022
35185750Physician-Confirmed and Administrative Definitions of Stroke in UK Biobank Reflect the Same Underlying Genetic Trait.Front Neurol2022
33307546Genetic mechanisms of critical illness in COVID-19.Nature2021
35602207Genetic and phenotypic analysis of the causal relationship between aging and COVID-19.Commun Med (Lond)2021
33925473Changes in Plasma Metabolome Profiles Following Oral Glucose Challenge among Adult Chinese.Nutrients2021
33613642Nontrivial Replication of Loci Detected by Multi-Trait Methods.Front Genet2021
34857772Mapping the serum proteome to neurological diseases using whole genome sequencing.Nat Commun2021
34437946Non-inferiority in cancer clinical trials was associated with more lenient margins and higher hypothesized outcome event rates.J Clin Epidemiol2021
34504513Improved Estimation of Phenotypic Correlations Using Summary Association Statistics.Front Genet2021
33990588Total genetic contribution assessment across the human genome.Nat Commun2021
34245689Polygenic associations and causal inferences between serum immunoglobulins and amyotrophic lateral sclerosis.Clin Chim Acta2021
32601477High-definition likelihood inference of genetic correlations across human complex traits.Nat Genet2020
31221261Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals.J Am Coll Cardiol2019
31243447The genetic interplay between body mass index, breast size and breast cancer risk: a Mendelian randomization analysis.Int J Epidemiol2019
31382822Lipids, Apolipoproteins, and the Risk of Parkinson Disease.Circ Res2019
29437585MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank.Ann Rheum Dis2018
29875472Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.Sci Rep2018
28878392Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.Nat Commun2017
28338080Bivariate genomic analysis identifies a hidden locus associated with bacteria hypersensitive response in Arabidopsis thaliana.Sci Rep2017
29030599Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.Nat Commun2017
29198721A Selection Operator for Summary Association Statistics Reveals Allelic Heterogeneity of Complex Traits.Am J Hum Genet2017
27079753Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.Alzheimers Dement2016
27798627Genome-wide analysis identifies 12 loci influencing human reproductive behavior.Nat Genet2016
27226169Genetic Regulation of Transcriptional Variation in Natural Arabidopsis thaliana Accessions.G3 (Bethesda)2016
26992471Effects of number of training generations on genomic prediction for various traits in a layer chicken population.Genet Sel Evol2016
26059968Identification of quantitative genetic components of fitness variation in farmed, hybrid and native salmon in the wild.Heredity (Edinb)2015
26397943A Genome-Wide Association Analysis Reveals Epistatic Cancellation of Additive Genetic Variance for Root Length in Arabidopsis thaliana.PLoS Genet2015
26311298RE: The Effect on Melanoma Risk of Genes Previously Associated With Telomere Length.J Natl Cancer Inst2015
25503602Natural CMT2 variation is associated with genome-wide methylation changes and temperature seasonality.PLoS Genet2014
23335338A novel generalized ridge regression method for quantitative genetics.Genetics2013
24555098Issues with data transformation in genome-wide association studies for phenotypic variability.F1000Res2013
24122053MAPfastR: quantitative trait loci mapping in outbred line crosses.G3 (Bethesda)2013
24204378The curse of the missing heritability.Front Genet2013
23734164Beware of risk for increased false positive rates in genome-wide association studies for phenotypic variability.Front Genet2013
23508070PASE: a novel method for functional prediction of amino acid substitutions based on physicochemical properties.Front Genet2013
23497136Genetic dissection of growth traits in a Chinese indigenous ÿ commercial broiler chicken cross.BMC Genomics2013
22876191Inheritance beyond plain heritability: variance-controlling genes in Arabidopsis thaliana.PLoS Genet2012
21615912qtl.outbred: Interfacing outbred line cross data with the R/qtl mapping software.BMC Res Notes2011
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Collaborators

James F Wilson
Co-authored papers 13
Yudi Pawitan
Karolinska Institute
Co-authored papers 8
Caroline Hayward
Co-authored papers 7
Cornelia M van Duijn
University of Oxford
Co-authored papers 6
George Dedoussis
Co-authored papers 5
Charles Kooperberg
Co-authored papers 5
Pau Navarro
Co-authored papers 5
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Co-authored papers 5
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Co-authored papers 5
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Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
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Johns Hopkins University School of Medicine
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Co-authored papers 4
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Xiuqing Guo
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Bruce M Psaty
Co-authored papers 3
Massimo Mangino
Co-authored papers 3
Tim D Spector
King's College London
Co-authored papers 3
Allan Linneberg
Co-authored papers 3
Christian Fuchsberger
Co-authored papers 3
Ozren Polasek
Co-authored papers 3
Ulf Gyllensten
Co-authored papers 3
Bram P Prins
Co-authored papers 3
Release 1.2