Author details

Full Name

Lu-Yun Lian

Affiliation

Institute of Systems, The University of Liverpool

ORCID

Career Start Year

1984

Papers

139

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36550088	Probing Peptidylprolyl Bond cis/trans Status Using Distal <sup>19</sup> F NMR Reporters.	Chemistry	2023
34888671	CPVT-associated calmodulin variants N53I and A102V dysregulate Ca2+ signalling via different mechanisms.	J Cell Sci	2022
35533445	Development of chimeric forms of the matrix metalloproteinase 2 collagen binding domain as artificial membrane binding proteins for targeting stem cells to cartilage lesions in osteoarthritic joints.	Biomaterials	2022
35746469	Co-Administration of Adjuvanted Recombinant <i>Ov</i>-103 and <i>Ov</i>-RAL-2 Vaccines Confer Protection against Natural Challenge in A Bovine <i>Onchocerca ochengi</i> Infection Model of Human Onchocerciasis.	Vaccines (Basel)	2022
34163995	Identification of Î²-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation.	Chem Sci	2021
34402867	Metabolic profiling of maternal serum of women at high-risk of spontaneous preterm birth using NMR and MGWAS approach.	Biosci Rep	2021
32576835	Cyclophilin D binds to the acidic C-terminus region of Î±-Synuclein and affects its aggregation characteristics.	Sci Rep	2020
31866013	Interaction with the heparin-derived binding inhibitors destabilizes galectin-3 protein structure.	Biochem Biophys Res Commun	2020
31413267	Intrinsic tryptophan fluorescence spectroscopy reliably determines galectin-ligand interactions.	Sci Rep	2019
29729387	Characterisation of Anopheles gambiae heme oxygenase and metalloporphyrin feeding suggests a potential role in reproduction.	Insect Biochem Mol Biol	2018
30229649	<sup>1</sup>H NMR Metabolomics Identifies Underlying Inflammatory Pathology in Osteoarthritis and Rheumatoid Arthritis Synovial Joints.	J Proteome Res	2018
30296268	Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils.	PLoS Negl Trop Dis	2018
28662181	Structure of the Neisseria Adhesin Complex Protein (ACP) and its role as a novel lysozyme inhibitor.	PLoS Pathog	2017
28398555	Biophysical and functional characterization of hippocalcin mutants responsible for human dystonia.	Hum Mol Genet	2017
26950392	Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis.	J Med Chem	2016
27452402	Phosphorylation of Cysteine String Protein Triggers a Major Conformational Switch.	Structure	2016
27066458	Interaction of the Oncofetal Thomsen-Friedenreich Antigen with Galectins in Cancer Progression and Metastasis.	Front Oncol	2016
25979333	Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions.	J Biol Chem	2015
26160844	Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis.	Oncotarget	2015
26177569	Biochemical investigations of the mechanism of action of small molecules ZL006 and IC87201 as potential inhibitors of the nNOS-PDZ/PSD-95-PDZ interactions.	Sci Rep	2015
24712326	Trifluoroibuprofen inhibits Î±-methylacyl coenzyme A racemase (AMACR/P504S), reduces cancer cell proliferation and inhibits in vivo tumor growth in aggressive prostate cancer models.	Anticancer Agents Med Chem	2014
25279835	The structure, stability and pheromone binding of the male mouse protein sex pheromone darcin.	PLoS One	2014
25109970	Comparative study of the molecular variation between 'central' and 'peripheral' MUPs and significance for behavioural signalling.	Biochem Soc Trans	2014
25188201	Demonstration of binding of neuronal calcium sensor-1 to the cav2.1 p/q-type calcium channel.	Biochemistry	2014
23288833	Cooperative catalysis through noncovalent interactions.	Angew Chem Int Ed Engl	2013
23890519	A report of 2 new cases of MODY2 and review of the literature: implications in the search for type 2 diabetes drugs.	Metabolism	2013
23895101	Structure-based design of PDZ ligands as inhibitors of 5-HT(2A) receptor/PSD-95 PDZ1 domain interaction possessing anti-hyperalgesic activity.	ACS Chem Biol	2013
23929631	Inhibition of human Î±-methylacyl CoA racemase (AMACR): a target for prostate cancer.	ChemMedChem	2013
23611315	NMR studies of weak protein-protein interactions.	Prog Nucl Magn Reson Spectrosc	2013
23545111	Identification of PDZ ligands by docking-based virtual screening for the development of novel analgesic agents.	Bioorg Med Chem Lett	2013
23274113	Metastasis-promoting anterior gradient 2 protein has a dimeric thioredoxin fold structure and a role in cell adhesion.	J Mol Biol	2013
22140111	The structure and selectivity of the SR protein SRSF2 RRM domain with RNA.	Nucleic Acids Res	2012
23028322	Structure and assembly of a trans-periplasmic channel for type IV pili in Neisseria meningitidis.	PLoS Pathog	2012
22989873	Solution NMR structure of the Ca2+-bound N-terminal domain of CaBP7: a regulator of golgi trafficking.	J Biol Chem	2012
22955930	In support of the BMRB.	Nat Struct Mol Biol	2012
22848679	NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast.	PLoS One	2012
22483112	Asymmetric mode of CaÂ²âº-S100A4 interaction with nonmuscle myosin IIA generates nanomolar affinity required for filament remodeling.	Structure	2012
22480236	Evidence for metabolic cleavage of a PEGylated protein in vivo using multiple analytical methodologies.	Mol Pharm	2012
22644296	Splice variant PRKC-Î¶(-PrC) is a novel biomarker of human prostate cancer.	Br J Cancer	2012
22242544	Conformational characterization of synapse-associated protein 97 by nuclear magnetic resonance and small-angle X-ray scattering shows compact and elongated forms.	Biochemistry	2012
20703835	The 1H, 13C and 15N backbone and side-chain assignment of the RRM domain of SC35, a regulator of pre-mRNA splicing.	Biomol NMR Assign	2011
22114693	Characterisation of the interaction of the C-terminus of the dopamine D2 receptor with neuronal calcium sensor-1.	PLoS One	2011
21530246	NMR evaluation of interactions between substituted-indole and PDZ1 domain of PSD-95.	Bioorg Med Chem Lett	2011
21655236	Biochemical comparison of Anopheles gambiae and human NADPH P450 reductases reveals different 2'-5'-ADP and FMN binding traits.	PLoS One	2011
21324359	Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed.	Insect Biochem Mol Biol	2011
19797610	Quantifying the metabolic activation of nevirapine in patients by integrated applications of NMR and mass spectrometries.	Drug Metab Dispos	2010
21779455	PRKC-Î¶ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention.	Genes Cancer	2010
20703836	1H, 15N and 13C resonance assignment of darcin, a mouse major urinary protein.	Biomol NMR Assign	2010
20479890	Structural and functional deficits in a neuronal calcium sensor-1 mutant identified in a case of autistic spectrum disorder.	PLoS One	2010
19032153	Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission in Caenorhabditis elegans.	Biochem J	2009

1 - 50 of 139

Yang Shen

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Career Start Year 2002

Number of shared co-authors 4

Ronald D Seidel

Albert Einstein College of Medicine

Career Start Year 2001

Number of shared co-authors 2

Mark J S Kelly

Department of Pharmaceutical Chemistry, University of California San Francisco

Career Start Year 2000

Number of shared co-authors 5

Anthony P Duff

Bragg Institute

Career Start Year 2000

Number of shared co-authors 1

Igor Zhukov

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

Career Start Year 1999

Number of shared co-authors 1

Rodrigo J Carbajo

Oncology R&D

Career Start Year 1997

Number of shared co-authors 2

Witek Kwiatkowski

Swiss Federal Institute of Technology

Career Start Year 1996

Number of shared co-authors 1

Volker D??tsch

Institute for Biophysical Chemistry, Goethe-University

Career Start Year 1995

Number of shared co-authors 5

Ram??n Campos-Olivas

Spanish National Cancer Research Centre (CNIO)

Career Start Year 1995

Number of shared co-authors 2

John R Cort

Pacific Northwest National Laboratory

Career Start Year 1994

Number of shared co-authors 0

Diana R Tomchick

University of Texas Southwestern Medical Center

Career Start Year 1993

Number of shared co-authors 7

Michael A Kennedy

Miami University

Career Start Year 1993

Number of shared co-authors 5

James J Chou

Harvard Medical School

Career Start Year 1993

Number of shared co-authors 5

Gye Won Han

Bridge Institute, University of Southern California

Career Start Year 1991

Number of shared co-authors 1

Maria Sunnerhagen

Linkoping University

Career Start Year 1989

Number of shared co-authors 4

Cheryl H Arrowsmith

University of Toronto

Career Start Year 1989

Number of shared co-authors 17

P??r Nordlund

Karolinska Institutet, BioClinicum J6

Career Start Year 1989

Number of shared co-authors 3

Steven C Almo

Albert Einstein College of Medicine

Career Start Year 1988

Number of shared co-authors 4

Raymond C Stevens

iHuman Institute, ShanghaiTech University

Career Start Year 1988

Number of shared co-authors 4

Roland Riek

ETH Zurich

Career Start Year 1986

Number of shared co-authors 7

Thomas B Acton

Center for Advanced Biotechnology and Medicine, The State University of New Jersey

Career Start Year 1986

Number of shared co-authors 5

Michael Nilges

Institut Pasteur

Career Start Year 1986

Number of shared co-authors 21

Gaetano T Montelione

Rensselaer Polytechnic Institute

Career Start Year 1981

Number of shared co-authors 13

Peter Bayer

University of Duisburg-Essen

Career Start Year 1981

Number of shared co-authors 3

Hans J Vogel

University of Calgary

Career Start Year 1979

Number of shared co-authors 0

Martino Bolognesi

University of Milano

Career Start Year 1975

Number of shared co-authors 3

George N Phillips

Rice University

Career Start Year 1974

Number of shared co-authors 5

David Cowburn

Albert Einstein College of Medicine

Career Start Year 1969

Number of shared co-authors 4

Wayne A Hendrickson

Columbia University

Career Start Year 1968

Number of shared co-authors 1

Robert M Stroud

University of California San Francisco

Career Start Year 1965

Number of shared co-authors 3

row(s) 1 - 30 of 30

Gordon C K Roberts

Leicester Institute of Structural and Chemical Biology, University of Leicester

Co-authored papers 37

Alexander P Golovanov

The University of Manchester

Co-authored papers 15

Igor L Barsukov

Institute of Integrative Biology, University of Liverpool

Co-authored papers 12

Guillaume M Hautbergue

Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield

Co-authored papers 9

Colin Kleanthous

Co-authored papers 5

Robert J Beynon

Co-authored papers 3

Jane L Hurst

Co-authored papers 3

C Jeremy Craven

University of Sheffield

Co-authored papers 3

Christopher S Foster

The Institute of Cancer Research

Co-authored papers 2

Colin S Cooper

Norwich Medical School, University of East Anglia

Co-authored papers 2

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

Matthew P Crump

University of Bristol

Co-authored papers 1

David A Case

Rutgers University

Co-authored papers 1

Oliver F Lange

Center for Integrated Protein Science, Technische Universitat Munchen

Co-authored papers 1

Josep Rizo

University of Texas Southwestern Medical Center

Co-authored papers 1

Mike P Williamson

The University of Sheffield

Co-authored papers 1

David E Shaw

Columbia University

Co-authored papers 1

Ad Bax

National Institutes of Health

Co-authored papers 1

Patrick C A van der Wel

Zernike Institute for Advanced Materials, University of Groningen

Co-authored papers 1

David Middleton

Co-authored papers 1

Ioannis Vakonakis

University of Oxford

Co-authored papers 1

Thomas A Frenkiel

The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute

Co-authored papers 1

Ernest D Laue

University of Cambridge

Co-authored papers 1

Gordon S Rule

Carnegie Mellon University

Co-authored papers 1

Stephen Matthews

Imperial College London

Co-authored papers 1

Chien Ho

Carnegie Mellon University

Co-authored papers 1

Toshimichi Fujiwara

Institute for Protein Research, Osaka University

Co-authored papers 1

Pei Tang

Sichuan University

Co-authored papers 1

Joern Werner

Co-authored papers 1

Paul C Driscoll

The Francis Crick Institute

Co-authored papers 1

1 - 30

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