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Author Details

Marcello Marelli
AstraZeneca Oncology R&D
1995
34
18
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37007587Engineered Ultrasmall Nanoparticle Drug-Immune Conjugates with "Hit and Run" Tumor Delivery to Eradicate Gastric Cancer.Adv Ther (Weinh)2023
35943835Cyclopentadiene as a Multifunctional Reagent for Normal- and Inverse-Electron Demand Diels-Alder Bioconjugation.Bioconjug Chem2022
33674305PD-L1<sup>+</sup> neutrophils contribute to injury-induced infection susceptibility.Sci Adv2021
31775561Development of a high yielding expression platform for the introduction of non-natural amino acids in protein sequences.MAbs2020
30536645Amber suppression coupled with inducible surface display identifies cells with high recombinant protein productivity.Biotechnol Bioeng2019
31380623A Reactive Antibody Platform for One-Step Production of Antibody-Drug Conjugates through a Diels-Alder Reaction with Maleimide.Bioconjug Chem2019
31018033A Diene-Containing Noncanonical Amino Acid Enables Dual Functionality in Proteins: Rapid Diels-Alder Reaction with Maleimide or Proximity-Based Dimerization.Angew Chem Int Ed Engl2019
31071154qPCR assays to quantitate tRNApyl and pylRS expression in engineered cell lines.PLoS One2019
30912649Improved Inhibition of Tumor Growth by Diabody-Drug Conjugates via Half-Life Extension.Bioconjug Chem2019
30900513Functional mimetic of the G-protein coupled receptor CXCR4 on a soluble antibody scaffold.MAbs2019
29400603A novel bicistronic gene design couples stable cell line selection with a fucose switch in a designer CHO host to produce native and afucosylated glycoform antibodies.MAbs2018
30753634Tag-on-Demand: exploiting amber codon suppression technology for the enrichment of high-expressing membrane protein cell lines.Protein Eng Des Sel2018
30297810Ultrasmall targeted nanoparticles with engineered antibody fragments for imaging detection of HER2-overexpressing breast cancer.Nat Commun2018
28890364Sequential screening by ClonePix FL and intracellular staining facilitate isolation of high producer cell lines for monoclonal antibody manufacturing.J Immunol Methods2017
28832690Development of a fluorescent reporter system for monitoring ER stress in Chinese hamster ovary cells and its application for therapeutic protein production.PLoS One2017
26271488AZ17: a new bispecific drug targeting IL-6 and IL-23 with potential clinical use--improves psoriasis in a human xenograft transplantation model.Protein Eng Des Sel2015
26332743Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody-Drug Conjugates Using Click Cycloaddition Chemistry.Bioconjug Chem2015
20026609Dynamic changes in the subcellular distribution of Gpd1p in response to cell stress.J Biol Chem2010
18370030Identifying bona fide components of an organelle by isotope-coded labeling of subcellular fractions : an example in peroxisomes.Methods Mol Biol2008
17551510Transcriptional responses to fatty acid are coordinated by combinatorial control.Mol Syst Biol2007
16936734Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast.Nat Genet2006
16738555Expression and functional profiling reveal distinct gene classes involved in fatty acid metabolism.Mol Syst Biol2006
15596542Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane.J Cell Biol2004
14517321Pex11-related proteins in peroxisome dynamics: a role for the novel peroxin Pex27p in controlling peroxisome size and number in Saccharomyces cerevisiae.Mol Biol Cell2003
12403813Karyopherins in nuclear pore biogenesis: a role for Kap121p in the assembly of Nup53p into nuclear pore complexes.J Cell Biol2002
12298092Approaching complete peroxisome characterization by gas-phase fractionation.Electrophoresis2002
12135984Transcriptome profiling to identify genes involved in peroxisome assembly and function.J Cell Biol2002
11716302The dynamics of karyopherin-mediated nuclear transport.Biochem Cell Biol2001
11352933A link between the synthesis of nucleoporins and the biogenesis of the nuclear envelope.J Cell Biol2001
9988776Topology and functional domains of the yeast pore membrane protein Pom152p.J Biol Chem1999
9864357Specific binding of the karyopherin Kap121p to a subunit of the nuclear pore complex containing Nup53p, Nup59p, and Nup170p.J Cell Biol1998
9101091Inhibition of junction assembly in cultured epithelial cells by hepatocyte growth factor/scatter factor is concomitant with increased stability and altered phosphorylation of the soluble junctional molecules.Cell Growth Differ1997
9111320The peroxin Pex17p of the yeast Yarrowia lipolytica is associated peripherally with the peroxisomal membrane and is required for the import of a subset of matrix proteins.Mol Cell Biol1997
8522578Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p.J Cell Biol1995
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Collaborators

John D Aitchison
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Co-authored papers 14
Jennifer J Smith
Institute for Systems Biology
Co-authored papers 7
Richard A Rachubinski
University of Alberta
Co-authored papers 7
Richard W Wozniak
University of Alberta
Co-authored papers 6
David R Goodlett
University of Victoria
Co-authored papers 3
Daehee Hwang
Co-authored papers 2
Alexey I Nesvizhskii
University of Michigan ann arbor
Co-authored papers 2
Stephen A Ramsey
Oregon State University
Co-authored papers 2
Rowan H Christmas
Co-authored papers 2
Franco J Vizeacoumar
College of Medicine, University of Saskatchewan
Co-authored papers 2
David J Dilworth
Institute for Systems Biology
Co-authored papers 2
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Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 2
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The Rockefeller University
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Larry Norton
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Pacific Northwest National Laboratory
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Timothy Galitski
Institute for Systems Biology
Co-authored papers 1
Raghothama Chaerkady
Co-authored papers 1
Trey Ideker (CM4AI)
University of California San Diego
Co-authored papers 1
Mithat Gonen
Co-authored papers 1
G??nter Blobel
Howard Hughes Medical Institute, The Rockefeller University
Co-authored papers 1
Release 1.2