Author details

Full Name

Jian Yang

Affiliation

ORCID

Career Start Year

2001

Papers

204

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36658102	Association of Thyroid-Stimulating Hormone With All-Cause Mortality: A 2-Sample Mendelian Randomization Study.		2023
37601976	Joint analysis of GWAS and multi-omics QTL summary statistics reveals a large fraction of GWAS signals shared with molecular phenotypes.	Cell Genom	2023
36864651	Genetic risk, muscle strength and risk of incident major depressive disorder: results from the UK Biobank.		2023
36797296	Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility.	Nat Commun	2023
36608683	mBAT-combo: A more powerful test to detect gene-trait associations from GWAS data.	Am J Hum Genet	2023
37505983	Chromosomal inversion polymorphisms shape human brain morphology.	Cell Rep	2023
37500768	Maternal aging increases offspring adult body size via transmission of donut-shaped mitochondria.		2023
35113692	Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases.	Science	2022
35610986	Parsimonious model for mass-univariate vertexwise analysis.	J Med Imaging (Bellingham)	2022
35982161	Genetic control of RNA splicing and its distinct role in complex trait variation.	Nature Genetics	2022
34635651	FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth.	Nature Communications	2021
32398722	Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders.	Mol Psychiatry	2021
33811805	Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals.	Am J Hum Genet	2021
33542196	Multi-omic and multi-species meta-analyses of nicotine consumption.	Transl Psychiatry	2021
33856023	Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction.	Hum Mol Genet	2021
33961780	Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals.	Am J Hum Genet	2021
34214457	Genomic partitioning of inbreeding depression in humans.	Am J Hum Genet	2021
33664403	Quantifying genetic heterogeneity between continental populations for human height and body mass index.	Scientific Reports	2021
33828259	Towards the understanding of the genetics of somatic mutations.	British Journal of Cancer	2021
33608517	Widespread signatures of natural selection across human complex traits and functional genomic categories.	Nat Commun	2021
33558551	Publisher Correction: Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes.	Nat Commun	2021
33436567	Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes.	Nat Commun	2021
34325683	Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study.	BMC Medicine	2021
33594080	Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals.	Nat Commun	2021
33549134	Genetic and functional interaction network analysis reveals global enrichment of regulatory T cell genes influencing basal cell carcinoma susceptibility.	Genome Med	2021
33419773	Tumor Mutational Burden Is Polygenic and Genetically Associated with Complex Traits and Diseases.	Cancer Research	2021
34737426	A generalized linear mixed model association tool for biobank-scale data.	Nature Genetics	2021
34381240	Retraction Note: Detection and replication of epistasis influencing transcription in humans.	Nature	2021
34381229	Phantom epistasis between unlinked loci.	Nature	2021
34480422	The genomics of heart failure: design and rationale of the HERMES consortium.	ESC Heart Fail	2021
34880243	Improved analyses of GWAS summary statistics by reducing data heterogeneity and errors.	Nature Communications	2021
34363226	Transient Receptor Potential channels, TRPV1 and TRPA1 in melanocytes synergize UV-dependent and UV-independent melanogenesis.	British Journal of Pharmacology	2021
34475573	Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.	Nat Genet	2021
31074781	Exploring the role of genetic confounding in the association between maternal and offspring body mass index: evidence from three birth cohorts.	Int J Epidemiol	2020
32144264	Analysis of DNA methylation associates the cystine-glutamate antiporter SLC7A11 with risk of Parkinson's disease.	Nat Commun	2020
32140259	Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis.	NPJ Genom Med	2020
32077750	Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Scores and Linear Mixed Models.	J Comput Biol	2020
32423524	The SNP-Based Heritability - A Commentary on Yang etÂ al. (2010).	Twin Research and Human Genetics	2020
32242144	Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration.	Nat Commun	2020
32345984	Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data.	Nat Commun	2020
32103259	Tissue specific regulation of transcription in endometrium and association with disease.	Human Reproduction	2020
33032658	The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases.	Microbiome	2020
32687259	A unified framework for association and prediction from vertex-wise grey-matter structure.	Hum Brain Mapp	2020
32737319	Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations.	Nature Communications	2020
33067605	Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.	Nat Metab	2020
31044242	Tissue-specific sex differences in human gene expression.	Human Molecular Genetics	2019
31856883	Genotype-free demultiplexing of pooled single-cell RNA-seq.	Genome Biol	2019
31636407	Genetic correlates of social stratification in Great Britain.	Nat Hum Behav	2019
31892350	An epigenome-wide association study of sex-specific chronological ageing.	Genome Med	2019
31768069	A resource-efficient tool for mixed model association analysis of large-scale data.	Nat Genet	2019