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Author Details

John A Leigh
University of Washingtongrid.34477.33
1983
79
43
PMIDPaper TitleJournal TitlePublished Year
35107346A Genetic Study of <i>Nif</i>-Associated Genes in a Hyperthermophilic Methanogen.Microbiol Spectr2022
27736793Exploring Hydrogenotrophic Methanogenesis: a Genome Scale Metabolic Reconstruction of Methanococcus maripaludis.J Bacteriol2016
24662145Metabolic versatility in methanogens.Curr Opin Biotechnol2014
24844759Hydrogenase-independent uptake and metabolism of electrons by the archaeon Methanococcus maripaludis.ISME J2014
23335420Effects of H2 and formate on growth yield and regulation of methanogenesis in Methanococcus maripaludis.J Bacteriol2013
24039260VhuD facilitates electron flow from H2 or formate to heterodisulfide reductase in Methanococcus maripaludis.J Bacteriol2013
24089473A systems level predictive model for global gene regulation of methanogenesis in a hydrogenotrophic methanogen.Genome Res2013
23443005H2-independent growth of the hydrogenotrophic methanogen Methanococcus maripaludis.mBio2013
23551135Phenotypic evidence that the function of the [Fe]-hydrogenase Hmd in Methanococcus maripaludis requires seven hcg (hmd co-occurring genes) but not hmdII.FEMS Microbiol Lett2013
22872868Essential anaplerotic role for the energy-converting hydrogenase Eha in hydrogenotrophic methanogenesis.Proc Natl Acad Sci U S A2012
22739494Functional responses of methanogenic archaea to syntrophic growth.ISME J2012
21265868Model organisms for genetics in the domain Archaea: methanogens, halophiles, Thermococcales and Sulfolobales.FEMS Microbiol Rev2011
21750103Parallel evolution of transcriptome architecture during genome reorganization.Genome Res2011
21402212Growth of methanogens under defined hydrogen conditions.Methods Enzymol2011
21402209Genetic systems for hydrogenotrophic methanogens.Methods Enzymol2011
20025661Overlapping repressor binding sites regulate expression of the Methanococcus maripaludis glnK(1) operon.Mol Microbiol2010
21070950Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR.Structure2010
20534465Protein complexing in a methanogen suggests electron bifurcation and electron delivery from formate to heterodisulfide reductase.Proc Natl Acad Sci U S A2010
20581182Interdomain conjugal transfer of DNA from bacteria to archaea.Appl Environ Microbiol2010
19671178Comprehensive computational analysis of Hmd enzymes and paralogs in methanogenic Archaea.BMC Evol Biol2009
19627604Quantitative proteomics of nutrient limitation in the hydrogenotrophic methanogen Methanococcus maripaludis.BMC Microbiol2009
18203827Global responses of Methanococcus maripaludis to specific nutrient limitations and growth rate.J Bacteriol2008
18791018Formate-dependent H2 production by the mesophilic methanogen Methanococcus maripaludis.Appl Environ Microbiol2008
18487331Roles of coenzyme F420-reducing hydrogenases and hydrogen- and F420-dependent methylenetetrahydromethanopterin dehydrogenases in reduction of F420 and production of hydrogen during methanogenesis.J Bacteriol2008
17456186Diverse homologues of the archaeal repressor NrpR function similarly in nitrogen regulation.FEMS Microbiol Lett2007
17950693NifI inhibits nitrogenase by competing with Fe protein for binding to the MoFe protein.Biochem Biophys Res Commun2007
17639608Protein abundance ratios for global studies of prokaryotes.Proteomics2007
17720835Genetic screen for regulatory mutations in Methanococcus maripaludis and its use in identification of induction-deficient mutants of the euryarchaeal repressor NrpR.Appl Environ Microbiol2007
17353934Metabolic modeling of a mutualistic microbial community.Mol Syst Biol2007
17506680Nitrogen regulation in bacteria and archaea.Annu Rev Microbiol2007
17502615Functionally distinct genes regulated by hydrogen limitation and growth rate in methanogenic Archaea.Proc Natl Acad Sci U S A2007
16452419Disruption of the operon encoding Ehb hydrogenase limits anabolic CO2 assimilation in the archaeon Methanococcus maripaludis.J Bacteriol2006
17124542Comparison of spectral counting and metabolic stable isotope labeling for use with quantitative microbial proteomics.Analyst2006
16777963Regulation of nitrogenase by 2-oxoglutarate-reversible, direct binding of a PII-like nitrogen sensor protein to dinitrogenase.Proc Natl Acad Sci U S A2006
16489187Quantitative proteomics of the archaeon Methanococcus maripaludis validated by microarray analysis and real time PCR.Mol Cell Proteomics2006
15659675Markerless mutagenesis in Methanococcus maripaludis demonstrates roles for alanine dehydrogenase, alanine racemase, and alanine permease.J Bacteriol2005
159166032-Oxoglutarate and the PII homologues NifI1 and NifI2 regulate nitrogenase activity in cell extracts of Methanococcus maripaludis.Mol Microbiol2005
15590692Regulation of nif expression in Methanococcus maripaludis: roles of the euryarchaeal repressor NrpR, 2-oxoglutarate, and two operators.J Biol Chem2005
15336407Continuous culture of Methanococcus maripaludis under defined nutrient conditions.FEMS Microbiol Lett2004
15466049Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis.J Bacteriol2004
12492867A novel repressor of nif and glnA expression in the methanogenic archaeon Methanococcus maripaludis.Mol Microbiol2003
12670979Function and regulation of the formate dehydrogenase genes of the methanogenic archaeon Methanococcus maripaludis.J Bacteriol2003
11932238The genome of M. acetivorans reveals extensive metabolic and physiological diversity.Genome Res2002
12218015Regulatory response of Methanococcus maripaludis to alanine, an intermediate nitrogen source.J Bacteriol2002
11208785Ammonia switch-off of nitrogen fixation in the methanogenic archaeon Methanococcus maripaludis: mechanistic features and requirement for the novel GlnB homologues, NifI(1) and NifI(2).J Bacteriol2001
11471757Nitrogen fixation in methanogens: the archaeal perspective.Curr Issues Mol Biol2000
9864338Function and regulation of glnA in the methanogenic archaeon Methanococcus maripaludis.J Bacteriol1999
10322164Transcriptional regulation in Archaea.Curr Opin Microbiol1999
10220900Functional conservation between the argininosuccinate lyase of the archaeon Methanococcus maripaludis and the corresponding bacterial and eukaryal genes.FEMS Microbiol Lett1999
10430565Genetics of nitrogen regulation in Methanococcus maripaludis.Genetics1999
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Lawrence Berkeley National Laboratory
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Altius Institute for Biomedical Sciences
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Albert Einstein College of Medicine
Co-authored papers 1
University of Georgia
Co-authored papers 1
University of Washington
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Eli Lilly and Co.
Co-authored papers 1
Joint BioEnergy Institute
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Fred Hutchinson Cancer Research Center
Co-authored papers 1
Institute for Genome Sciences, University of Maryland School of Medicine
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Vanderbilt-Ingram Cancer Center, Vanderbilt University
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Environmental Microbiomics Research Center, Sun Yat-Sen University
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