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Author Details
Full Name
John A Leigh
Affiliation
University of Washingtongrid.34477.33
ORCID
Career Start Year
1983
Papers
79
H Index
43
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
35107346
A Genetic Study of <i>Nif</i>-Associated Genes in a Hyperthermophilic Methanogen.
Microbiol Spectr
2022
27736793
Exploring Hydrogenotrophic Methanogenesis: a Genome Scale Metabolic Reconstruction of Methanococcus maripaludis.
J Bacteriol
2016
24662145
Metabolic versatility in methanogens.
Curr Opin Biotechnol
2014
24844759
Hydrogenase-independent uptake and metabolism of electrons by the archaeon Methanococcus maripaludis.
ISME J
2014
23335420
Effects of H2 and formate on growth yield and regulation of methanogenesis in Methanococcus maripaludis.
J Bacteriol
2013
24039260
VhuD facilitates electron flow from H2 or formate to heterodisulfide reductase in Methanococcus maripaludis.
J Bacteriol
2013
24089473
A systems level predictive model for global gene regulation of methanogenesis in a hydrogenotrophic methanogen.
Genome Res
2013
23443005
H2-independent growth of the hydrogenotrophic methanogen Methanococcus maripaludis.
mBio
2013
23551135
Phenotypic evidence that the function of the [Fe]-hydrogenase Hmd in Methanococcus maripaludis requires seven hcg (hmd co-occurring genes) but not hmdII.
FEMS Microbiol Lett
2013
22872868
Essential anaplerotic role for the energy-converting hydrogenase Eha in hydrogenotrophic methanogenesis.
Proc Natl Acad Sci U S A
2012
22739494
Functional responses of methanogenic archaea to syntrophic growth.
ISME J
2012
21265868
Model organisms for genetics in the domain Archaea: methanogens, halophiles, Thermococcales and Sulfolobales.
FEMS Microbiol Rev
2011
21750103
Parallel evolution of transcriptome architecture during genome reorganization.
Genome Res
2011
21402212
Growth of methanogens under defined hydrogen conditions.
Methods Enzymol
2011
21402209
Genetic systems for hydrogenotrophic methanogens.
Methods Enzymol
2011
20025661
Overlapping repressor binding sites regulate expression of the Methanococcus maripaludis glnK(1) operon.
Mol Microbiol
2010
21070950
Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR.
Structure
2010
20534465
Protein complexing in a methanogen suggests electron bifurcation and electron delivery from formate to heterodisulfide reductase.
Proc Natl Acad Sci U S A
2010
20581182
Interdomain conjugal transfer of DNA from bacteria to archaea.
Appl Environ Microbiol
2010
19671178
Comprehensive computational analysis of Hmd enzymes and paralogs in methanogenic Archaea.
BMC Evol Biol
2009
19627604
Quantitative proteomics of nutrient limitation in the hydrogenotrophic methanogen Methanococcus maripaludis.
BMC Microbiol
2009
18203827
Global responses of Methanococcus maripaludis to specific nutrient limitations and growth rate.
J Bacteriol
2008
18791018
Formate-dependent H2 production by the mesophilic methanogen Methanococcus maripaludis.
Appl Environ Microbiol
2008
18487331
Roles of coenzyme F420-reducing hydrogenases and hydrogen- and F420-dependent methylenetetrahydromethanopterin dehydrogenases in reduction of F420 and production of hydrogen during methanogenesis.
J Bacteriol
2008
17456186
Diverse homologues of the archaeal repressor NrpR function similarly in nitrogen regulation.
FEMS Microbiol Lett
2007
17950693
NifI inhibits nitrogenase by competing with Fe protein for binding to the MoFe protein.
Biochem Biophys Res Commun
2007
17639608
Protein abundance ratios for global studies of prokaryotes.
Proteomics
2007
17720835
Genetic screen for regulatory mutations in Methanococcus maripaludis and its use in identification of induction-deficient mutants of the euryarchaeal repressor NrpR.
Appl Environ Microbiol
2007
17353934
Metabolic modeling of a mutualistic microbial community.
Mol Syst Biol
2007
17506680
Nitrogen regulation in bacteria and archaea.
Annu Rev Microbiol
2007
17502615
Functionally distinct genes regulated by hydrogen limitation and growth rate in methanogenic Archaea.
Proc Natl Acad Sci U S A
2007
16452419
Disruption of the operon encoding Ehb hydrogenase limits anabolic CO2 assimilation in the archaeon Methanococcus maripaludis.
J Bacteriol
2006
17124542
Comparison of spectral counting and metabolic stable isotope labeling for use with quantitative microbial proteomics.
Analyst
2006
16777963
Regulation of nitrogenase by 2-oxoglutarate-reversible, direct binding of a PII-like nitrogen sensor protein to dinitrogenase.
Proc Natl Acad Sci U S A
2006
16489187
Quantitative proteomics of the archaeon Methanococcus maripaludis validated by microarray analysis and real time PCR.
Mol Cell Proteomics
2006
15659675
Markerless mutagenesis in Methanococcus maripaludis demonstrates roles for alanine dehydrogenase, alanine racemase, and alanine permease.
J Bacteriol
2005
15916603
2-Oxoglutarate and the PII homologues NifI1 and NifI2 regulate nitrogenase activity in cell extracts of Methanococcus maripaludis.
Mol Microbiol
2005
15590692
Regulation of nif expression in Methanococcus maripaludis: roles of the euryarchaeal repressor NrpR, 2-oxoglutarate, and two operators.
J Biol Chem
2005
15336407
Continuous culture of Methanococcus maripaludis under defined nutrient conditions.
FEMS Microbiol Lett
2004
15466049
Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis.
J Bacteriol
2004
12492867
A novel repressor of nif and glnA expression in the methanogenic archaeon Methanococcus maripaludis.
Mol Microbiol
2003
12670979
Function and regulation of the formate dehydrogenase genes of the methanogenic archaeon Methanococcus maripaludis.
J Bacteriol
2003
11932238
The genome of M. acetivorans reveals extensive metabolic and physiological diversity.
Genome Res
2002
12218015
Regulatory response of Methanococcus maripaludis to alanine, an intermediate nitrogen source.
J Bacteriol
2002
11208785
Ammonia switch-off of nitrogen fixation in the methanogenic archaeon Methanococcus maripaludis: mechanistic features and requirement for the novel GlnB homologues, NifI(1) and NifI(2).
J Bacteriol
2001
11471757
Nitrogen fixation in methanogens: the archaeal perspective.
Curr Issues Mol Biol
2000
9864338
Function and regulation of glnA in the methanogenic archaeon Methanococcus maripaludis.
J Bacteriol
1999
10322164
Transcriptional regulation in Archaea.
Curr Opin Microbiol
1999
10220900
Functional conservation between the argininosuccinate lyase of the archaeon Methanococcus maripaludis and the corresponding bacterial and eukaryal genes.
FEMS Microbiol Lett
1999
10430565
Genetics of nitrogen regulation in Methanococcus maripaludis.
Genetics
1999
1 - 50 of 79
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