Author details

Full Name

Kay-Hooi Khoo

Affiliation

ORCID

Career Start Year

1990

Papers

234

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37502146	High Density of N- and O-Glycosylation Shields and Defines the Structural Dynamics of the Intrinsically Disordered Ectodomain of Receptor-type Protein Tyrosine Phosphatase Alpha.		2023
36089405	Roles of Siglecs in neurodegenerative diseases.	Molecular Aspects of Medicine	2023
37271932	An N-glycopeptide MS/MS data analysis workflow leveraging two complementary glycoproteomic software tools for more confident identification and assignments.		2023
37440446	Expression of low-sulfated keratan sulfate in non-mucinous ovarian carcinoma.		2023
37367667	Species-Specific -Glycomes and Methylation Patterns of Oysters and and Their Possible Consequences for the Norovirus-HBGA Interaction.		2023
34893784	Author Correction: Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis.	Nat Methods	2022
35846945	Engineering microparticles based on solidified stem cell secretome with an augmented pro-angiogenic factor portfolio for therapeutic angiogenesis.	Bioactive Materials	2022
35711441	Molecular Basis and Role of Siglec-7 Ligand Expression on Chronic Lymphocytic Leukemia B Cells.	Front Immunol	2022
35831428	An embeddable molecular code for Lewis X modification through interaction with fucosyltransferase 9.	Communications Biology	2022
36216861	N-glycosylation of cervicovaginal fluid reflects microbial community, immune activity, and pregnancy status.	Sci Rep	2022
35743105	Cancer Malignancy Is Correlated with Upregulation of PCYT2-Mediated Glycerol Phosphate Modification of Î±-Dystroglycan.	International Journal of Molecular Sciences	2022
35986008	In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.	Nature Communications	2022
34735575	Distinct shifts in site-specific glycosylation pattern of SARS-CoV-2 spike proteins associated with arising mutations in the D614G and Alpha variants.	Glycobiology	2022
34583196	Establishment of a novel monoclonal antibody against truncated glycoforms of Î±-dystroglycan lacking matriglycans.	Biochemical and Biophysical Research Communications	2021
33492355	A mass spectrometry-based glycotope-centric cellular glycomics is the more fruitful way forward to see the forest for the trees.	Biochemical Society Transactions	2021
33688734	Production of Structurally Defined Chito-Oligosaccharides with a Single -Acetylation at Their Reducing End Using a Newly Discovered Chitinase from .	Journal of Agricultural and Food Chemistry	2021
33177111	Sialylation of CD55 by ST3GAL1 Facilitates Immune Evasion in Cancer.	Cancer Immunology Research	2021
34988116	Discovery Sulfoglycomics and Identification of the Characteristic Fragment Ions for High-Sensitivity Precise Mapping of Adult Zebrafish Brain-Specific Glycotopes.	Frontiers in Molecular Biosciences	2021
34725484	Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis.	Nat Methods	2021
34780171	ZIC-cHILIC-Based StageTip for Simultaneous Glycopeptide Enrichment and Fractionation toward Large-Scale N-Sialoglycoproteomics.	Anal Chem	2021
34661385	Carbohydrate Sulfation As a Mechanism for Fine-Tuning Siglec Ligands.	ACS Chemical Biology	2021
34824473	Glycoproteomic software solutions spotlight glycans.	Nature Methods	2021
33659290	Permethylation and Microfractionation of Sulfated Glycans for MS Analysis.	Bio-protocol	2020
31900356	Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans.	Proceedings of the National Academy of Sciences of the United States of America	2020
31932432	The nutrient sensor OGT regulates Hipk stability and tumorigenic-like activities in .	Proceedings of the National Academy of Sciences of the United States of America	2020
32156778	Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity.	Cancer Res	2020
32384234	Strategic Applications of Negative-Mode LC-MS/MS Analyses to Expedite Confident Mass Spectrometry-Based Identification of Multiple Glycosylated Peptides.	Analytical Chemistry	2020
32270793	Mycobacterium bovis BCG infection alters the macrophage N-glycome.	Molecular Omics	2020
33659291	Negative Ion Mode nanoLC-ESI-MS/MS Analyses of Permethylated Sulfated Glycans.	Bio-protocol	2020
30709055	Novel Zebrafish Mono-Î±2,8-sialyltransferase (ST8Sia VIII): An Evolutionary Perspective of Î±2,8-Sialylation.	International Journal of Molecular Sciences	2019
31455764	Functional roles of ST8SIA3-mediated sialylation of striatal dopamine D and adenosine A receptors.	Translational Psychiatry	2019
30884379	Advances toward mapping the full extent of protein site-specific O-GalNAc glycosylation that better reflects underlying glycomic complexity.	Current Opinion in Structural Biology	2019
29540535	Target identification reveals protein arginine methyltransferase 1 is a potential target of phenyl vinyl sulfone and its derivatives.	Bioscience Reports	2018
30405127	Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns.	Nature Communications	2018
30118680	Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1.	Molecular Cell	2018
30146545	Identifying Specific and Differentially Linked Glycosyl Residues in Mammalian Glycans by Targeted LC-MS Analysis.	Analytical Sciences	2018
30093410	Distinct substrate specificities of human GlcNAc-6-sulfotransferases revealed by mass spectrometry-based sulfoglycomic analysis.	Journal of Biological Chemistry	2018
29765556	Antibody-assisted target identification reveals afatinib, an EGFR covalent inhibitor, down-regulating ribonucleotide reductase.	Oncotarget	2018
29765039	STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.	Nat Commun	2018
29619343	Alterations of the Human Skin - and -Glycome in Basal Cell Carcinoma and Squamous Cell Carcinoma.	Frontiers in Oncology	2018
29438695	Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1.	Cancer Cell	2018
29087466	Concerted mass spectrometry-based glycomic approach for precision mapping of sulfo sialylated N-glycans on human peripheral blood mononuclear cells and lymphocytes.	Glycobiology	2018
29644550	Distinctive and Complementary MS Fragmentation Characteristics for Identification of Sulfated Sialylated N-Glycopeptides by nanoLC-MS/MS Workflow.	Journal of the American Society for Mass Spectrometry	2018
27993942	The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data.	Glycobiology	2017
29050309	Fibronectin in cell adhesion and migration via N-glycosylation.	Oncotarget	2017
28353332	Adapting Data-Independent Acquisition for Mass Spectrometry-Based Protein Site-Specific N-Glycosylation Analysis.	Anal Chem	2017
29066631	Advancing a High Throughput Glycotope-centric Glycomics Workflow Based on nanoLC-MS-product Dependent-MS Analysis of Permethylated Glycans.	Molecular and Cellular Proteomics	2017
27555448	Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells.	Nat Commun	2016
27143722	Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity.	Proceedings of the National Academy of Sciences of the United States of America	2016
27572267	Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity.	Nat Commun	2016