Author details

Full Name

Klaus Ley

Affiliation

ORCID

Career Start Year

1982

Papers

462

H Index

124

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37291737	V<sub>4</sub> C<sub>3</sub> MXene Immune Profiling and Modulation of T Cell-Dendritic Cell Function and Interaction.	Small Methods	2023
36190844	Integrated single-cell analysis-based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis.	Cardiovascular Research	2023
37563308	Identification of human exT cells as CD16CD56 cytotoxic CD4 T cells.		2023
37621765	Pairing of single-cell RNA analysis and T cell antigen receptor profiling indicates breakdown of T cell tolerance checkpoints in atherosclerosis.		2023
37471165	Single-cell profiling reveals inflammatory polarization of human carotid versus femoral plaque leukocytes.		2023
37284819	Mast cells must stick.		2023
37205656	HIV infection and cardiovascular disease have both shared and distinct monocyte gene expression features: Women's Interagency HIV study.		2023
36579643	How Lymphatic Endothelial Cells Destabilize Regulatory T Cells.		2023
37499656	Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis.	Immunity	2023
35097011	Chemokine Receptor Activation Enhances Memory B Cell Class Switching Linked to IgE Sensitization to Alpha Gal and Cardiovascular Disease.	Front Cardiovasc Med	2022
36311776	Olfactory receptors in macrophages and inflammation.	Frontiers in Immunology	2022
36045343	Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells.	BMC Biology	2022
35840527	De-stressing plaques attenuates atherosclerosis progression.	Trends in Immunology	2022
35766025	Immunodominant MHC-II (Major Histocompatibility Complex II) Restricted Epitopes in Human Apolipoprotein B.	Circ Res	2022
36231001	Structural Basis of Î²2 Integrin Inside-Out Activation.	Cells	2022
35649374	A humanized Î² integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation inÂ vivo.	Cell Reports	2022
36207284	Immune Profiling and Multiplexed Label-Free Detection of 2D MXenes by Mass Cytometry and High-Dimensional Imaging.	Adv Mater	2022
36134519	Small matters: Introduction to extracellular vesicles.	Immunological Reviews	2022
35990517	Single cell transcriptomics and TCR reconstruction reveal CD4 T cell response to MHC-II-restricted APOB epitope in human cardiovascular disease.	Nat Cardiovasc Res	2022
36266696	Author Correction: Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells.	BMC Biology	2022
35665941	The expanding family of neutrophil-derived extracellular vesicles.	Immunological Reviews	2022
36574991	Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development.	Life Sci Alliance	2022
36496494	Deleting interleukin-10 from myeloid cells exacerbates atherosclerosis in Apoe mice.		2022
36684560	Single-cell transcriptomes and T cell receptors of vaccine-expanded apolipoprotein B-specific T cells.		2022
36460735	Titration of 124 antibodies using CITE-Seq on human PBMCs.	Scientific Reports	2022
35238344	Neutrophil ion currents matter.	Cardiovascular Research	2022
35238001	Flow Cytometry and Mass Cytometry for Measuring the Immune Cell Infiltrate in Atherosclerotic Arteries.	Methods in Molecular Biology	2022
35238000	Single-Cell Antibody Sequencing in Atherosclerosis Research.	Methods in Molecular Biology	2022
34389841	How the immune system shapes atherosclerosis: roles of innate and adaptive immunity.	Nature Reviews Immunology	2022
35025664	Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production.	Science	2022
35167661	Molecular mechanisms of leukocyte Î²2 integrin activation.	Blood	2022
35097028	Autoimmune Regulator (AIRE) Deficiency Does Not Affect Atherosclerosis and CD4 T Cell Immune Tolerance to Apolipoprotein B.	Frontiers in Cardiovascular Medicine	2021
34078665	Data-Driven Kidney Transplant Phenotyping as a Histology-Independent Framework for Biomarker Discovery.	Journal of the American Society of Nephrology : JASN	2021
33970188	Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain.	J Exp Med	2021
33589816	A CD22-Shp1 phosphatase axis controls integrin Î²<sub>7</sub> display and B cell function in mucosal immunity.	Nat Immunol	2021
34073130	Biomechanics of Neutrophil Tethers.	Life	2021
33744912	Fortified Tregs to fight atherosclerosis.	Cardiovascular Research	2021
34068931	Inflammation and Atherosclerosis.	Cells	2021
34162836	CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition.	Nature Communications	2021
33991749	Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe mice.	Molecular Metabolism	2021
33827251	Predicting Gene Expression From Computed Tomography Angiography.	Arteriosclerosis, Thrombosis, and Vascular Biology	2021
34343272	Heterogeneity of immune cells in human atherosclerosis revealed by scRNA-Seq.	Cardiovascular Research	2021
33275138	Elongated neutrophil-derived structures are blood-borne microparticles formed by rolling neutrophils during sepsis.	J Exp Med	2021
32777822	Kindlin-3 recruitment to the plasma membrane precedes high-affinity Î²2-integrin and neutrophil arrest from rolling.	Blood	2021
32658258	Classical monocyte transcriptomes reveal significant anti-inflammatory statin effect in women with chronic HIV.	Cardiovascular Research	2021
34740961	Thymus-Derived CD4CD8 Cells Reside in Mediastinal Adipose Tissue and the Aortic Arch.	Journal of Immunology	2021
34458258	Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis.	Front Cell Dev Biol	2021
34544271	Endothelial Heparan Sulfate Mediates Hepatic Neutrophil Trafficking and Injury during Staphylococcus aureus Sepsis.	mBio	2021
31475386	Frontline Science: A flexible kink in the transmembrane domain impairs Î²2 integrin extension and cell arrest from rolling.	J Leukoc Biol	2020
32324494	Single Cell RNA Sequencing in Atherosclerosis Research.	Circulation Research	2020