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Author Details

Sakura Minami
Dokkyo Medical University
2006
24
17
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36934154CCR3 plays a role in murine age-related cognitive changes and T-cell infiltration into the brain.Commun Biol2023
35971662Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice.Brain Behav2022
33737065Effects of methylazoxymethanol-induced micrencephaly on parvalbumin-positive GABAergic interneurons in the rat rostral basolateral amygdala.Brain Res2021
28404863Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.Sci Transl Med2017
28438992Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.Proc Natl Acad Sci U S A2017
27041503Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.Neuron2016
25589773SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.J Neurosci2015
26390242Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.Nat Med2015
26206194Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.Biochem Pharmacol2015
25155018Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD.J Exp Med2014
25261995Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.Nat Med2014
23083210Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease.J Neurochem2013
21741124Fyn knock-down increases Aβ, decreases phospho-tau, and worsens spatial learning in 3ÿTg-AD mice.Neurobiol Aging2012
22272874Selective targeting of microglia by quantum dots.J Neuroinflammation2012
21534960Fyn kinase regulates the association between amyloid precursor protein and Dab1 by promoting their localization to detergent-resistant membranes.J Neurochem2011
21872217Decreased dendritic spine density and abnormal spine morphology in Fyn knockout mice.Brain Res2011
19720620The cytoplasmic adaptor protein X11alpha and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement.FASEB J2010
20920207Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aβ/amyloid burden in a transgenic mouse model of Alzheimer's disease.J Neuroinflammation2010
20406479ApoE mimetic peptide decreases Abeta production in vitro and in vivo.Mol Neurodegener2010
18089558Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing.J Biol Chem2008
18486110Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model.Brain Res2008
17478890Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage.J Mol Neurosci2007
16736464Chemotopic representations of aromatic odorants in the rat olfactory bulb.J Comp Neurol2006
17083447BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild-type mice.J Neurochem2006
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Buck Institute for Research on Aging
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Jiangsu Simcere Pharmaceutical Co. Ltd.
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UCSF Weill Institute for Neurosciences, University of California san francisco
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Buck Institute for Research on Aging
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