Skip to Main Content

Author Details

Koh Fujinaga
University of California at San Francisco
1994
73
30
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36599353P-TEFb: The master regulator of transcription elongation.Mol Cell2023
36055411DCAF1 inhibits the NF-κB pathway by targeting p65.Immunol Lett2022
35524561P-TEFb is degraded by Siah1/2 in quiescent cells.Nucleic Acids Res2022
36280456Corrigendum to 'DCAF1 inhibits the NF-κB pathway by targeting p65'[Immunology Letters 249 (2022) 33-42].Immunol Lett2022
34821217Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb.Elife2021
32176734Nucleolar protein NOP2/NSUN1 suppresses HIV-1 transcription and promotes viral latency by competing with Tat for TAR binding and methylation.PLoS Pathog2020
32075058P-TEFb as A Promising Therapeutic Target.Molecules2020
33182414Experimental Systems for Measuring HIV Latency and Reactivation.Viruses2020
30824372P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic Stress.Mol Cell2019
31238957Fused in sarcoma silences HIV gene transcription and maintains viral latency through suppressing AFF4 gene activation.Retrovirology2019
29463681Bromodomain-containing protein 4-independent transcriptional activation by autoimmune regulator (AIRE) and NF-κB.J Biol Chem2018
30395647HEXIM1-Tat chimera inhibits HIV-1 replication.PLoS Pathog2018
29673219HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV Therapies.Molecules2018
28931682Susceptibility of Human Endogenous Retrovirus Type K to Reverse Transcriptase Inhibitors.J Virol2017
28331090Hili Inhibits HIV Replication in Activated T Cells.J Virol2017
26783762The two sides of Tat.Elife2016
27977742Euphorbia Kansui Reactivates Latent HIV.PLoS One2016
27365398FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator).J Biol Chem2016
27058786Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.Mol Cell2016
26731470Molecular mechanisms of HIV latency.J Clin Invest2016
25384976Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts.Mol Cell Biol2015
26567509CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing.Cell Host Microbe2015
26225566An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression.PLoS Pathog2015
25492871Visualization of positive transcription elongation factor b (P-TEFb) activation in living cells.J Biol Chem2015
24636995Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat.Mol Cell Biol2014
24917669Genetic analysis of the structure and function of 7SK small nuclear ribonucleoprotein (snRNP) in cells.J Biol Chem2014
24515107Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription.J Biol Chem2014
23539624Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription.J Biol Chem2013
21453127Activation of P-TEFb at sites of dual HIV/TB infection, and inhibition of MTB-induced HIV transcriptional activation by the inhibitor of CDK9, Indirubin-3'-monoxime.AIDS Res Hum Retroviruses2012
22952229Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein.J Biol Chem2012
22821562PKC phosphorylates HEXIM1 and regulates P-TEFb activity.Nucleic Acids Res2012
22342181Functional characterization of a human cyclin T1 mutant reveals a different binding surface for Tat and HEXIM1.Virology2012
20661303HIV-1 inhibits autophagy in bystander macrophage/monocytic cells through Src-Akt and STAT3.PLoS One2010
20064163Cyclin T1 stabilizes expression levels of HIV-1 Tat in cells.FEBS J2009
18620576Dominant negative mutant cyclin T1 proteins inhibit HIV transcription by specifically degrading Tat.Retrovirology2008
18757415HEXIM1 regulates 17beta-estradiol/estrogen receptor-alpha-mediated expression of cyclin D1 in mammary cells via modulation of P-TEFb.Cancer Res2008
18931076Dominant negative mutant cyclin T1 proteins that inhibit HIV transcription by forming a kinase inactive complex with Tat.J Gen Virol2008
18662700The positive transcription elongation factor b is an essential cofactor for the activation of transcription by myocyte enhancer factor 2.J Mol Biol2008
17540406Cyclin box structure of the P-TEFb subunit cyclin T1 derived from a fusion complex with EIAV tat.J Mol Biol2007
15940264The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1.Oncogene2005
14701750Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element.Mol Cell Biol2004
11739744Interaction between P-TEFb and the C-terminal domain of RNA polymerase II activates transcriptional elongation from sites upstream or downstream of target genes.Mol Cell Biol2002
12368330Optimized chimeras between kinase-inactive mutant Cdk9 and truncated cyclin T1 proteins efficiently inhibit Tat transactivation and human immunodeficiency virus gene expression.J Virol2002
12438619A minimal chimera of human cyclin T1 and tat binds TAR and activates human immunodeficiency virus transcription in murine cells.J Virol2002
11958689Extracellular Nef protein activates signal transduction pathway from Ras to mitogen-activated protein kinase cascades that leads to activation of human immunodeficiency virus from latency.AIDS Res Hum Retroviruses2002
11884399P-TEFb containing cyclin K and Cdk9 can activate transcription via RNA.J Biol Chem2002
11880033Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA.Chem Biol2002
10623752Interactions between equine cyclin T1, Tat, and TAR are disrupted by a leucine-to-valine substitution found in human cyclin T1.J Virol2000
10906320Flavopiridol inhibits P-TEFb and blocks HIV-1 replication.J Biol Chem2000
10846086Binding of Tat to TAR and recruitment of positive transcription elongation factor b occur independently in bovine immunodeficiency virus.J Virol2000
  • 1 - 50 of 73

Recommended Authors

Simon Langer
University Hospital of Wurzburg
Career Start Year 2012
Number of shared co-authors 1
Zichong Li
Gladstone Center for HIV Cure Research, Gladstone Institute of Virology
Career Start Year 2011
Number of shared co-authors 2
Huasong Lu
Life Sciences Institute, Zhejiang University
Career Start Year 2011
Number of shared co-authors 4
Tyler B Faust
Dana-Farber Cancer Institute
Career Start Year 2010
Number of shared co-authors 2
Yuhua Xue
School of Pharmaceutical Sciences, Xiamen University
Career Start Year 2008
Number of shared co-authors 2
Lara Manganaro
National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi"
Career Start Year 2005
Number of shared co-authors 1
Haran Sivakumaran
QIMR Berghofer Medical Research Institute
Career Start Year 2005
Number of shared co-authors 0
Gwendolyn M Jang
Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes
Career Start Year 2004
Number of shared co-authors 4
Nanhai He
Adlai Nortye USA Inc.
Career Start Year 2004
Number of shared co-authors 2
Kotaro Shirakawa
Graduate School of Medicine, Kyoto University
Career Start Year 2004
Number of shared co-authors 2
Felipe Diaz-Griffero
Albert Einstein College of Medicine
Career Start Year 2002
Number of shared co-authors 1
Shweta Hakre
AstraZeneca Pharmaceuticals
Career Start Year 2002
Number of shared co-authors 1
Sumit K Chanda
The Scripps Research Institute
Career Start Year 2001
Number of shared co-authors 5
Tokameh Mahmoudi
Erasmus University Medical Center
Career Start Year 1999
Number of shared co-authors 1
Iv??n D'Orso
University of Texas Southwestern Medical Center
Career Start Year 1998
Number of shared co-authors 4
Renate K??nig
Paul-Ehrlich-Institut
Career Start Year 1998
Number of shared co-authors 2
Melanie Ott
Gladstone Institute of Virology
Career Start Year 1993
Number of shared co-authors 4
Lubbertus C F Mulder
Icahn School of Medicine at Mount Sinai
Career Start Year 1993
Number of shared co-authors 2
Ren Sun
University of California los angeles
Career Start Year 1992
Number of shared co-authors 2
Vicente Planelles
University of Utah
Career Start Year 1991
Number of shared co-authors 1
Tariq M Rana
Institute for Genomic Medicine, University of California San Diego
Career Start Year 1990
Number of shared co-authors 1
Pavel Sova
Altius Institute for Biomedical Sciences
Career Start Year 1990
Number of shared co-authors 0
Joe S Mymryk
University of Western Ontario
Career Start Year 1989
Number of shared co-authors 0
Qiang Zhou
The University of Hong Kong
Career Start Year 1989
Number of shared co-authors 5
Ivan Sadowski
University of British Columbia
Career Start Year 1984
Number of shared co-authors 1
Eric Verdin
Buck Institute for Research on Aging
Career Start Year 1983
Number of shared co-authors 4
Michael Emerman
Fred Hutchinson Cancer Center
Career Start Year 1982
Number of shared co-authors 4
John Guatelli
University of California San Diego, USA VA San Diego Healthcare System
Career Start Year 1978
Number of shared co-authors 4
Warner C Greene
Gladstone Institute of Virology, USA University of California san francisco
Career Start Year 1971
Number of shared co-authors 5
Robert G Roeder
the Rockefeller University
Career Start Year 1969
Number of shared co-authors 1

Collaborators

Boris Matija Peterlin
University of California at San Francisco
Co-authored papers 33
Daniele C Cary
University of California san francisco
Co-authored papers 6
Zeping Luo
University of California at San Francisco
Co-authored papers 5
Koen Bartholomeeusen
Institute of Tropical Medicine
Co-authored papers 4
Wei Shao
Inc., Frederick National Laboratory for Cancer Research
Co-authored papers 4
Tristan Eifler
University of California at San Francisco
Co-authored papers 2
Stefanie J??ger
Institute of Molecular Biosciences, Goethe University Frankfurt
Co-authored papers 2
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 2
Hana Paculova
University of Vermont
Co-authored papers 1
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Joy Baseke
Busitema University
Co-authored papers 1
Netty Santoso
The Ohio State University Wexner Medical Center
Co-authored papers 1
Arthur Weiss
University of California san francisco
Co-authored papers 1
Ignacia Echeverria
University of California san francisco
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Yongmei Feng
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Caroline C Friedel
Institute of Informatics, Ludwig-Maximilians-Universitat Munchen
Co-authored papers 1
Trang Tt Nguyen
University of California san francisco
Co-authored papers 1
Howard Y Chang
Center for Personal Dynamic Regulomes, Stanford University
Co-authored papers 1
Tae Hoon Kim
Co-authored papers 1
Brian T Do
Center for Personal Dynamic Regulomes, Stanford University
Co-authored papers 1
Vladimir Pak
University of California san francisco
Co-authored papers 1
Ramachandran Rakesh
University of California san francisco
Co-authored papers 1
Ryan A Flynn
Boston Children's Hospital
Co-authored papers 1
Fang Huang
University of California san francisco
Co-authored papers 1
Mark D Adams
Case Western Reserve University School of Medicine
Co-authored papers 1
Richard M White
Memorial Sloan Kettering Cancer Center
Co-authored papers 1
Harriet Mayanja-Kizza
Case Western Reserve University
Co-authored papers 1
Release 1.2