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Author Details

James J Hsieh
Washington University
1994
167
65
PMIDPaper TitleJournal TitlePublished Year
36810256SETD2 regulates chromatin accessibility and transcription to suppress lung tumorigenesis.JCI Insight2023
36973268Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma.Nat Commun2023
37198186Author Correction: Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma.Nat Commun2023
36810256SETD2 regulates chromatin accessibility and transcription to suppress lung tumorigenesis.JCI Insight2023
36973268Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma.Nat Commun2023
37198186Author Correction: Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma.Nat Commun2023
35115713SETD2 loss perturbs the kidney cancer epigenetic landscape to promote metastasis and engenders actionable dependencies on histone chaperone complexes.Nat Cancer2022
36288724Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer.Immunity2022
35576438Telaglenastat plus Everolimus in Advanced Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled, Phase II ENTRATA Trial.Clin Cancer Res2022
35944503Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes.Cancer Cell2022
35977503Multiregional single-cell proteogenomic analysis of ccRCC reveals cytokine drivers of intratumor spatial heterogeneity.Cell Rep2022
35115713SETD2 loss perturbs the kidney cancer epigenetic landscape to promote metastasis and engenders actionable dependencies on histone chaperone complexes.Nat Cancer2022
35576438Telaglenastat plus Everolimus in Advanced Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled, Phase II ENTRATA Trial.Clin Cancer Res2022
36288724Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer.Immunity2022
35977503Multiregional single-cell proteogenomic analysis of ccRCC reveals cytokine drivers of intratumor spatial heterogeneity.Cell Rep2022
35944503Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes.Cancer Cell2022
34088495The 2021 Variant Histology Issue.Clin Genitourin Cancer2021
33784495Structural insights into the function of the catalytically active human Taspase1.Structure2021
34156981Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA.JCI Insight2021
33771855Single-cell Spatial Proteomic Revelations on the Multiparametric MRI Heterogeneity of Clinically Significant Prostate Cancer.Clin Cancer Res2021
33610279The 2021 COVID-19 Artificial Intelligence Issue.Clin Genitourin Cancer2021
34143969Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastatic renal cell carcinoma (Study 111/KEYNOTE-146): a phase 1b/2 study.Lancet Oncol2021
33657295Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma.N Engl J Med2021
34088495The 2021 Variant Histology Issue.Clin Genitourin Cancer2021
33867192A Single-arm, Multicenter, Phase 2 Study of Lenvatinib Plus Everolimus in Patients with Advanced Non-Clear Cell Renal Cell Carcinoma.Eur Urol2021
34316321Resource-efficient pooled sequencing expands translational impact in solid tumors.Kidney Cancer J2021
34389275Diagnostic Utility of RNA-Seq for Evaluation of PD-L1 Expression in Clear Cell Renal Cell Carcinoma.Clin Genitourin Cancer2021
34388376Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis.Cancer Cell2021
33657295Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma.N Engl J Med2021
33867192A Single-arm, Multicenter, Phase 2 Study of Lenvatinib Plus Everolimus in Patients with Advanced Non-Clear Cell Renal Cell Carcinoma.Eur Urol2021
33784495Structural insights into the function of the catalytically active human Taspase1.Structure2021
33610279The 2021 COVID-19 Artificial Intelligence Issue.Clin Genitourin Cancer2021
33771855Single-cell Spatial Proteomic Revelations on the Multiparametric MRI Heterogeneity of Clinically Significant Prostate Cancer.Clin Cancer Res2021
34389275Diagnostic Utility of RNA-Seq for Evaluation of PD-L1 Expression in Clear Cell Renal Cell Carcinoma.Clin Genitourin Cancer2021
34388376Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis.Cancer Cell2021
34156981Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA.JCI Insight2021
34316321Resource-efficient pooled sequencing expands translational impact in solid tumors.Kidney Cancer J2021
34143969Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastatic renal cell carcinoma (Study 111/KEYNOTE-146): a phase 1b/2 study.Lancet Oncol2021
32291161The Efficacy of Lenvatinib Plus Everolimus in Patients with Metastatic Renal Cell Carcinoma Exhibiting Primary Resistance to Front-Line Targeted Therapy or Immunotherapy.Clin Genitourin Cancer2020
32130964The Therapeutic Landscape of Renal Cell Carcinoma: From the Dark Age to the Golden Age.Semin Nephrol2020
31959902Molecular characterization of sarcomatoid clear cell renal cell carcinoma unveils new candidate oncogenic drivers.Sci Rep2020
32417157Elective Cytoreductive Nephrectomy After Checkpoint Inhibitor Immunotherapy in Patients With Initially Unresectable Metastatic Clear Cell Renal Cell Carcinoma.Clin Genitourin Cancer2020
32291161The Efficacy of Lenvatinib Plus Everolimus in Patients with Metastatic Renal Cell Carcinoma Exhibiting Primary Resistance to Front-Line Targeted Therapy or Immunotherapy.Clin Genitourin Cancer2020
31923397Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma.Cell2020
32332851Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts.Nat Commun2020
32273127The Gender Issue.Clin Genitourin Cancer2020
32768132The 2020 Kidney Cancer Treatment Sequence Issue.Clin Genitourin Cancer2020
32534803The 2020 Bladder Cancer Discrepancy Issue.Clin Genitourin Cancer2020
33308691The 2020 nccRCC Immunotherapy Issue.Clin Genitourin Cancer2020
33195887The Pan-Omics Landscape of Renal Cell Carcinoma and Its Implication on Future Clinical Practice.Kidney Cancer2020
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Collaborators

Co-authored papers 59
Memorial Sloan Kettering Cancer Center
Co-authored papers 22
Dana-Farber Cancer Institute
Co-authored papers 18
Broad Institute of MIT and Harvard
Co-authored papers 11
Co-authored papers 10
Johns Hopkins University School of Medicine
Co-authored papers 10
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Co-authored papers 8
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Englander Institute for Precision Medicine
Co-authored papers 7
Memorial Sloan Kettering Cancer Center
Co-authored papers 7
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University of California los angeles
Co-authored papers 6
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Mayo Clinic Arizona
Co-authored papers 6
Cleveland Clinic.
Co-authored papers 6
Co-authored papers 5
Van Andel Institute
Co-authored papers 5
Baylor College of Medicine
Co-authored papers 5
Baylor College of Medicine
Co-authored papers 5
Boston Children's Hospital
Co-authored papers 5
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Dana-Farber Cancer Institute
Co-authored papers 4
University of Lausanne (UNIL)
Co-authored papers 4
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Knight Cancer Institute, Oregon Health and Sciences University
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David Geffen School of Medicine, University of California-Los Angeles
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Present address: Dxige Research Inc.
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