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Author Details

Amber L Beitelshees
University of Maryland School of Medicine
2004
125
32
PMIDPaper TitleJournal TitlePublished Year
37425945Critical Role for 24-Hydroxylation in Homeostatic Regulation of Vitamin D Metabolism.medRxiv2024
37738423Vitamin D Deficiency Increases Vulnerability to Canagliflozin-induced Adverse Effects on 1,25-Dihydroxyvitamin D and PTH.J Clin Endocrinol Metab2024
37264484Acute pharmacodynamic responses to exenatide: Drug-induced increases in insulin secretion and glucose effectiveness.Diabetes Obes Metab2023
37593691Familial Hyperlipidemia Caused by Apolipoprotein B Mutation in the Pediatric Amish Population: A Mini Review.Interv Cardiol (Lond)2023
37608471Pharmacogenetics of sodium-glucose co-transporter-2 inhibitors: Validation of a sex-agnostic pharmacodynamic biomarker.Diabetes Obes Metab2023
35728944Excessive platelet inhibition following Pipeline embolization of intracranial aneurysms.J Neurointerv Surg2023
36993363Acute pharmacodynamic responses to exenatide: Drug-induced increases in insulin secretion and glucose effectiveness.medRxiv2023
37214882Vitamin D deficiency increases vulnerability to canagliflozin-induced adverse effects on 1,25-dihydroxyvitamin D and PTH.medRxiv2023
36945579Pharmacogenetics of SGLT2 Inhibitors: Validation of a sex-agnostic pharmacodynamic biomarker.medRxiv2023
37470135Predicting Heterogeneity in Patient Response to Morphine Treatment for Neonatal Opioid Withdrawal Syndrome.Clin Pharmacol Ther2023
34562070Multisite evaluation of institutional processes and implementation determinants for pharmacogenetic testing to guide antidepressant therapy.Clin Transl Sci2022
35652341Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension.Hypertension2022
35429163Impact of the ABCD-GENE Score on Clopidogrel Clinical Effectiveness after PCI: A Multi-Site, Real-World Investigation.Clin Pharmacol Ther2022
35568931Best-worst scaling methodology to evaluate constructs of the Consolidated Framework for Implementation Research: application to the implementation of pharmacogenetic testing for antidepressant therapy.Implement Sci Commun2022
35393526An Amish founder population reveals rare-population genetic determinants of the human lipidome.Commun Biol2022
35156424<i>CYP2C19</i> Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention in Diverse Clinical Settings.J Am Heart Assoc2022
32897581Impact of the CYP2C19*17 Allele on Outcomes in Patients Receiving Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.Clin Pharmacol Ther2021
34282303Multisite investigation of strategies for the clinical implementation of pre-emptive pharmacogenetic testing.Genet Med2021
33463546Pharmacological treatment of hyperglycemia in type 2 diabetes.J Clin Invest2021
33428770Opportunity for Genotype-Guided Prescribing Among Adult Patients in 11 US Health Systems.Clin Pharmacol Ther2021
32293069Sorting nexin 1 loss results in increased oxidative stress and hypertension.FASEB J2020
31891170Response to: Heterogeneous Treatment Response by Race Cannot Be Claimed in the Absence of Evidence.Am J Hypertens2020
32042096Cost-effectiveness of CYP2C19-guided antiplatelet therapy in patients with acute coronary syndrome and percutaneous coronary intervention informed by real-world data.Pharmacogenomics J2020
33315113Prescribing Prevalence of Medications With Potential Genotype-Guided Dosing in Pediatric Patients.JAMA Netw Open2020
33141630<i>KCNQ1</i> and Long QT Syndrome in 1/45 Amish: The Road From Identification to Implementation of Culturally Appropriate Precision Medicine.Circ Genom Precis Med2020
32747766Correction: Evaluating the extent of reusability of CYP2C19 genotype data among patients genotyped for antiplatelet therapy selection.Genet Med2020
32678355Evaluating the extent of reusability of CYP2C19 genotype data among patients genotyped for antiplatelet therapy selection.Genet Med2020
30753254Plasma Renin Activity Is a Predictive Biomarker of Blood Pressure Response in European but not in African Americans With Uncomplicated Hypertension.Am J Hypertens2019
31532792Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers.PLoS One2019
31585721SGLT2 inhibitors as adjunctive therapy for type 1 diabetes: balancing benefits and risks.Lancet Diabetes Endocrinol2019
31090079β<sub>2</sub> -Adrenergic Receptor Gene Affects the Heart Rate Response of β-Blockers: Evidence From 3 Clinical Studies.J Clin Pharmacol2019
31109940Sodium-Glucose Cotransporter 2 Inhibitors: A Case Study in Translational Research.Diabetes2019
30753892Effect of plasma MicroRNA on antihypertensive response to beta blockers in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) studies.Eur J Pharm Sci2019
29102571Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.JACC Cardiovasc Interv2018
29925376Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies.BMC Med Genomics2018
30289819Targeted sequencing identifies a missense variant in the BEST3 gene associated with antihypertensive response to hydrochlorothiazide.Pharmacogenet Genomics2018
29523524Genome Wide Association Study Identifies the <i>HMGCS2</i> Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients.J Am Heart Assoc2018
29478026Genome-Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β-Blockers.J Am Heart Assoc2018
29280137Multisite Investigation of Strategies for the Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy.Clin Pharmacol Ther2018
29167564Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics.Sci Rep2017
28294551The IGNITE Pharmacogenetics Working Group: An Opportunity for Building Evidence with Pharmacogenetic Implementation in a Real-World Setting.Clin Transl Sci2017
28115488Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response.Circ Cardiovasc Genet2017
29288159Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics.J Am Heart Assoc2017
28940643Blood pressure response to metoprolol and chlorthalidone in European and African Americans with hypertension.J Clin Hypertens (Greenwich)2017
29097388Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials.J Am Heart Assoc2017
26946962Melatonin Pathway and Atenolol-Related Glucose Dysregulation: Is There a Correlation?Clin Transl Sci2016
28217401Presence of arachidonoyl-carnitine is associated with adverse cardiometabolic responses in hypertensive patients treated with atenolol.Metabolomics2016
28217400Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach.Metabolomics2016
27423699User-centered design of multi-gene sequencing panel reports for clinicians.J Biomed Inform2016
27381900A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration.Hypertension2016
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Collaborators

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Toni I Pollin
University of Maryland School of Medicine
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Joshua P Lewis
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John A Spertus
University of Missouri-Kansas City School of Medicine
Co-authored papers 6
Nihal El Rouby
Department of Pharmacy Practice and Administrative Sciences, University of Cincinnati
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Mark R Vesely
University of Maryland Medical Center
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Wolfgang Sad??e
College of Medicine, The Ohio State University
Co-authored papers 6
Nicholas J Schork
University of California San Diego
Co-authored papers 6
Mark D Kelemen
University of Maryland
Co-authored papers 5
Michael A Province
Co-authored papers 5
Kristin A Maloney
University of Maryland School of Medicine
Co-authored papers 5
Sara L Van Driest
National Institutes of Health
Co-authored papers 5
Victoria M Pratt
Indiana University School of Medicine
Co-authored papers 4
Kathleen Palmer
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