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Author Details

Simone A Thair
Boston Children's Hospital
2010
24
15
PMIDPaper TitleJournal TitlePublished Year
36692131Multisite validation of a host response signature for predicting likelihood of bacterial and viral infections in patients with suspected influenza.Eur J Clin Invest2023
37533854Transcriptomic profiles of multiple organ dysfunction syndrome phenotypes in pediatric critical influenza.Front Immunol2023
36543117A robust host-response-based signature distinguishes bacterial and viral infections across diverse global populations.Cell Rep Med2022
34145026Profiling chromatin accessibility responses in human neutrophils with sensitive pathogen detection.Life Sci Alliance2021
33883455Gene Expression-Based Diagnosis of Infections in Critically Ill Patients-Prospective Validation of the SepsisMetaScore in a Longitudinal Severe Trauma Cohort.Crit Care Med2021
33437935Transcriptomic similarities and differences in host response between SARS-CoV-2 and other viral infections.iScience2020
30742071Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious disease.Nat Microbiol2019
29334679The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock.J Innate Immun2018
28165067Microbial Typing by Machine Learned DNA Melt Signatures.Sci Rep2017
26347487TNFAIP2 Inhibits Early TNFα-Induced NF-x03BA;B Signaling and Decreases Survival in Septic Shock Patients.J Innate Immun2016
25188548Identification of a nonsynonymous polymorphism in the SVEP1 gene associated with altered clinical outcomes in septic shock.Crit Care Med2015
25896417VPS13D Gene Variant Is Associated with Altered IL-6 Production and Mortality in Septic Shock.J Innate Immun2015
24335447A multibiomarker-based outcome risk stratification model for adult septic shock*.Crit Care Med2014
25320235PCSK9 is a critical regulator of the innate immune response and septic shock outcome.Sci Transl Med2014
23796235Vasopressin compared with norepinephrine augments the decline of plasma cytokine levels in septic shock.Am J Respir Crit Care Med2013
24244449Cytokines and signaling molecules predict clinical outcomes in sepsis.PLoS One2013
23975688Noncanonical Nuclear Factor Kappa B (NF-κB) Signaling and Potential for Therapeutics in Sepsis.Curr Infect Dis Rep2013
23151274Sepsis in transit: from clinical to molecular classification.Crit Care2012
21257964A single nucleotide polymorphism in NF-κB inducing kinase is associated with mortality in septic shock.J Immunol2011
21659747Molecular mechanisms of sepsis.Contrib Microbiol2011
21330387Leucyl/cystinyl aminopeptidase gene variants in septic shock.Chest2011
21423001Association of angiotensin II type 1 receptor-associated protein gene polymorphism with increased mortality in septic shock.Crit Care Med2011
19850944beta2-Adrenergic receptor gene polymorphism is associated with mortality in septic shock.Am J Respir Crit Care Med2010
21053993Exploiting the therapeutic potential of microRNAs in viral diseases: expectations and limitations.Mol Diagn Ther2010
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Collaborators

St. Paul's Hospital, University of British Columbia
Co-authored papers 15
University of British Columbia
Co-authored papers 13
University of British Columbia
Co-authored papers 13
St. Paul's Hospital, University of British Columbia
Co-authored papers 6
University of California San Francisco
Co-authored papers 4
Inflammatix Inc.
Co-authored papers 4
University of Pennsylvania Philadelphia
Co-authored papers 2
University of Pennsylvania Perelman School of Medicine
Co-authored papers 2
Vagelos College of Physicians and Surgeons, Columbia University
Co-authored papers 1
UCSF Benioff Children's Hospital Oakland
Co-authored papers 1
Phoenix Children's Hospital
Co-authored papers 1
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Cincinnati Children's Hospital Medical Center
Co-authored papers 1
Center for Personal Dynamic Regulomes, Stanford University School of Medicine
Co-authored papers 1
University of Helsinki and Helsinki University Hospital
Co-authored papers 1
Duke University
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Children's Hospital of Orange County
Co-authored papers 1
St. Jude Children's Research Hospital
Co-authored papers 1
Co-authored papers 1
Boston Children's Hospital, Harvard Medical School
Co-authored papers 1
Texas Children's Hospital
Co-authored papers 1
Tampere University Hospital
Co-authored papers 1
Center for Personal Dynamic Regulomes, Stanford University
Co-authored papers 1
Sustainable Sciences Institute
Co-authored papers 1
Medical College of Wisconsin and Children's Wisconsin
Co-authored papers 1
Co-authored papers 1
Sidney Kimmel Medical College at Thomas Jefferson University
Co-authored papers 1
Stanford University School of Medicine
Co-authored papers 1
Johns Hopkins University
Co-authored papers 1