Author details

Full Name

Aliaksandr Druz

Affiliation

ORCID

Career Start Year

2011

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
32268107	Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition.	Cell Rep	2020
30876875	Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.	Immunity	2019
31893251	Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B.	Pathogens and Immunity	2019
30604750	Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.	Nature Communications	2019
29451984	Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.	ACS Infect Dis	2018
29867235	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.	Nat Med	2018
30420505	Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.	Proc Natl Acad Sci U S A	2018
28275193	Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.	Journal of Virology	2017
28825711	Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.	Nature Chemical Biology	2017
28586323	Corrigendum: Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer.	Nat Struct Mol Biol	2017
28445724	Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.	Cell Rep	2017
29021918	Protection of calves by a prefusion-stabilized bovine RSV F vaccine.	npj Vaccines	2017
28514685	Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.	Immunity	2017
29212041	Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains.	Cell Reports	2017
28076415	Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.	PLoS Pathog	2017
28298421	Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.	Science Translational Medicine	2017
28218750	Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer.	Nat Struct Mol Biol	2017
27581986	Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site.	Journal of Virology	2016
27114034	Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G.	Cell	2016
27053554	Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design.	J Virol	2016
27174988	Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.	Science	2016
26949186	Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.	Cell	2016
27478931	Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.	Nat Struct Mol Biol	2016
27463224	Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus.	PLoS One	2016
27453470	Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.	Cell	2016
26689967	Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.	Nat Struct Mol Biol	2016
27573107	Platelet-derived growth factor-Î± receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer.	Nature Microbiology	2016
27851912	Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.	Immunity	2016
27820605	Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination.	Nat Med	2016
27583777	Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.	Bioconjugate Chemistry	2016
26098893	A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus.	PLoS One	2015
25740988	Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.	Journal of Virology	2015
26719262	Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody.	Journal of Virology	2015
26098315	Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env.	Nat Struct Mol Biol	2015
26004070	Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.	Cell	2015
26468542	New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency.	J Virol	2015
26468324	Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera.	Sci Transl Med	2015
25142607	Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo.	J Virol	2014
25296255	Structure and immune recognition of trimeric pre-fusion HIV-1 Env.	Nature	2014
24590074	Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.	Nature	2014
25186731	Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.	Nature	2014
23376592	Stable inhibition of mmu-miR-466h-5p improves apoptosis resistance and protein production in CHO cells.	Metabolic Engineering	2013
23916872	CHO microRNA engineering is growing up: recent successes and future challenges.	Biotechnology Advances	2013
23353574	Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines.	RNA Biol	2013
22638581	Glucose depletion activates mmu-miR-466h-5p expression through oxidative stress and inhibition of histone deacetylation.	Nucleic Acids Research	2012
21337326	A novel microRNA mmu-miR-466h affects apoptosis regulation in mammalian cells.	Biotechnology and Bioengineering	2011