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Author Details

Tristan W Owens
University of California san francisco
2011
14
12
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33411531Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through Highly Selective Binding to Phenylalanyl-tRNA Synthetase.J Am Chem Soc2021
33853786Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.Sci Adv2021
34013269CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.bioRxiv2021
34031651CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.Res Sq2021
33168989Structure and reconstitution of a hydrolase complex that may release peptidoglycan from the membrane after polymerization.Nat Microbiol2021
33060197Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.Science2020
30894747Structural basis of unidirectional export of lipopolysaccharide to the cell surface.Nature2019
31431556Combining Mutations That Inhibit Two Distinct Steps of the ATP Hydrolysis Cycle Restores Wild-Type Function in the Lipopolysaccharide Transporter and Shows that ATP Binding Triggers Transport.mBio2019
29402087Substrate Preferences Establish the Order of Cell Wall Assembly in Staphylococcus aureus.J Am Chem Soc2018
29746111Novobiocin Enhances Polymyxin Activity by Stimulating Lipopolysaccharide Transport.J Am Chem Soc2018
28727445Antibiotic That Inhibits the ATPase Activity of an ATP-Binding Cassette Transporter by Binding to a Remote Extracellular Site.J Am Chem Soc2017
29135241The Antibiotic Novobiocin Binds and Activates the ATPase That Powers Lipopolysaccharide Transport.J Am Chem Soc2017
27795402Identification of Residues in the Lipopolysaccharide ABC Transporter That Coordinate ATPase Activity with Extractor Function.mBio2016
21750194Stimulated association of STIM1 and Orai1 is regulated by the balance of PtdIns(4,5)Pâ¿¿ between distinct membrane pools.J Cell Sci2011
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Collaborators

Kaitlin Schaefer
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 5
Gregory E Merz
University of California san francisco
Co-authored papers 4
Michelle Moritz
University of California san francisco
Co-authored papers 4
James S Fraser
University of California san francisco
Co-authored papers 4
Natalia Jura
Cardiovascular Research Institute, University of California San Francisco
Co-authored papers 4
Ursula Schulze-Gahmen
Gladstone Institute of Virology, Gladstone Institutes San Francisco CA USA .
Co-authored papers 4
Huong T Kratochvil
Department of Pharmaceutical Chemistry, University of California-San Francisco
Co-authored papers 4
Jessica K Peters
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 4
Nadia Herrera
University of California san francisco
Co-authored papers 4
Aashish Manglik
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 3
Amber M Smith
University of California san francisco
Co-authored papers 3
Carlos Nowotny
University of California san francisco
Co-authored papers 3
Oren S Rosenberg
University of California san francisco
Co-authored papers 3
Yang Li
College of Chemistry, Jilin University
Co-authored papers 3
Axel F Brilot
University of California san francisco
Co-authored papers 3
Adam Frost
University of California San Francisco
Co-authored papers 3
Caleigh M Azumaya
Fred Hutchinson Cancer Center
Co-authored papers 3
Melody G Campbell
Fred Hutchinson Cancer Center
Co-authored papers 3
Erron W Titus
University of California san francisco
Co-authored papers 3
Christian B Billesb??lle
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 3
Tsz Kin Martin Tsui
University of California san francisco
Co-authored papers 3
Cristina Puchades
University of California San Francisco (UCSF) School of Medicine
Co-authored papers 3
Henry C Nguyen
Shanghai Clinical Research and Trial Center
Co-authored papers 3
Iris D Young
University of California san francisco
Co-authored papers 3
Jianhua Zhao
University of California san francisco
Co-authored papers 3
Fengbo Zhou
Washington University School of Medicine
Co-authored papers 3
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 3
David A Agard
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 3
Eric Tse
School of Clinical Medicine, University of Hong Kong
Co-authored papers 3
Lily Y-L Lee
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 3
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