Author details

Full Name

Mihaly Mezei

Affiliation

ORCID

Career Start Year

1983

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37767722	Functional Water Channels Within the TSH Receptor: A New Paradigm for TSH Action With Disease Implications.	Endocrinology	2023
37679563	Substrate binding and inhibition of the anion exchanger 1 transporter.	Nat Struct Mol Biol	2023
34812843	An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy.	J Exp Med	2022
35909553	Brief Report - Monoclonal Antibodies Illustrate the Difficulties in Measuring Blocking TSH Receptor Antibodies.	Front Endocrinol (Lausanne)	2022
36305581	Computational model of the full-length TSH receptor.	Elife	2022
36223484	Modeling TSH Receptor Dimerization at the Transmembrane Domain.	Endocrinology	2022
35298807	Tools for Characterizing Proteins: Circular Variance, Mutual Proximity, Chameleon Sequences, and Subsequence Propensities.	Methods in Molecular Biology	2022
32729941	Foldability and chameleon propensity of fold-switching protein sequences.	Proteins: Structure, Function and Bioinformatics	2021
31870208	Observation of quantum signature in rivastigmine chemical bond break-up and quantum energetics, spectral studies of anti-Alzheimer inhibitors.	Journal of Biomolecular Structure and Dynamics	2021
33803759	The Biological Significance of Targeting Acetylation-Mediated Gene Regulation for Designing New Mechanistic Tools and Potential Therapeutics.	Biomolecules	2021
33693584	Implications of an Improved Model of the TSH Receptor Transmembrane Domain (TSHR-TMD-TRIO).	Endocrinology	2021
31479556	On predicting foldability of a protein from its sequence.	Proteins: Structure, Function and Bioinformatics	2020
32596567	Protein Binding Pocket Optimization for Virtual High-Throughput Screening (vHTS) Drug Discovery.	ACS Omega	2020
32738139	The Human TSHÎ² Subunit Proteins and Their Binding Sites on the TSH Receptor Using Molecular Dynamics Simulation.	Endocrinology	2020
32676053	A Gq Biased Small Molecule Active at the TSH Receptor.	Front Endocrinol (Lausanne)	2020
32951964	Retro-inverso D-peptides as a novel targeted immunotherapy for Type 1 diabetes.	J Autoimmun	2020
30822352	A Modifying Autoantigen in Graves' Disease.	Endocrinology	2019
30479178	Virtual screening of a natural compound library at orthosteric and allosteric binding sites of the neurotensin receptor.	Journal of Biomolecular Structure and Dynamics	2019
30072621	Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3.	Molecules	2018
27862307	Rescore protein-protein docked ensembles with an interface contact statistics.	Proteins: Structure, Function and Bioinformatics	2017
28425495	The BigLEN-GPR171 Peptide Receptor System Within the Basolateral Amygdala Regulates Anxiety-Like Behavior and Contextual Fear Conditioning.		2017
28711758	Assessing the binding of cholinesterase inhibitors by docking and molecular dynamics studies.	Journal of Molecular Graphics and Modelling	2017
28925088	Comparison of a quantum random number generator with pseudorandom number generators for their use in molecular Monte Carlo simulations.	Journal of Computational Chemistry	2017
27729899	TSH Receptor Signaling Abrogation by a Novel Small Molecule.	Front Endocrinol (Lausanne)	2016
27245612	Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake.	Sci Signal	2016
27326334	Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7.	ACS Med Chem Lett	2016
26910498	In Silico Modeling of Novel Drug Ligands for Treatment of Concussion Associated Tauopathy.	J Cell Biochem	2016
26703475	Identifying a Small Molecule Blocking Antigen Presentation in Autoimmune Thyroiditis.	J Biol Chem	2016
26691434	The role of protein "Stability patches" in molecular recognition: A case study of the human growth hormone-receptor complex.	Journal of Computational Chemistry	2016
25012978	Monte Carlo loop refinement and virtual screening of the thyroid-stimulating hormone receptor transmembrane domain.	J Biomol Struct Dyn	2015
25333622	New small molecule agonists to the thyrotropin receptor.	Thyroid	2015
25406938	Transmembrane domains of attraction on the TSH receptor.	Endocrinology	2015
26078298	Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer.	Mol Cancer Ther	2015
26377607	Characterization of the Binding Site of Aspartame in the Human Sweet Taste Receptor.	Chemical Senses	2015
26702193	Use of circular variance to quantify the deviation of a macromolecule from the spherical shape.	Journal of Mathematical Chemistry	2015
25307013	Computational approaches for modeling GPCR dimerization.	Current Pharmaceutical Biotechnology	2014
23151229	Identification of a novel binding site between HIV type 1 Nef C-terminal flexible loop and AP2 required for Nef-mediated CD4 downregulation.	AIDS Res Hum Retroviruses	2013
22500075	Predicting protein interactions by Brownian dynamics simulations.		2012
22750979	Studies of base pair sequence effects on DNA solvation based on all-atom molecular dynamics simulations.		2012
22750978	The ABCs of molecular dynamics simulations on B-DNA, circa 2012.		2012
21935361	Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding.	PLoS One	2011
21142238	Discriminatory power of stoichiometry-driven protein folding?	Journal of Biomolecular Structure and Dynamics	2011
21534921	Molecular docking: a powerful approach for structure-based drug discovery.		2011
20205801	Dockres: a computer program that analyzes the output of virtual screening of small molecules.	Source Code for Biology and Medicine	2010
19731376	The energetics of the acetylation switch in p53-mediated transcriptional activation.	Proteins: Structure, Function and Bioinformatics	2010
20696915	Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor.	Proceedings of the National Academy of Sciences of the United States of America	2010
20740566	Simulaid: a simulation facilitator and analysis program.	Journal of Computational Chemistry	2010
20338845	A molecular dynamics investigation of lipid bilayer perturbation by PIP2.	Biophysical Journal	2010
19242538	Computer aided identification of small molecules disrupting uPAR/alpha5beta1--integrin interaction: a new paradigm for metastasis prevention.	PLoS ONE	2009
18507370	Homology modeling and site-directed mutagenesis to identify selective inhibitors of endothelin-converting enzyme-2.	Journal of Medicinal Chemistry	2008