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Author Details

William R Lumry
Allergy and Asthma Research Associates Research Center
1982
133
43
PMIDPaper TitleJournal TitlePublished Year
37730089Lanadelumab in Patients 2 to Less Than 12 Years Old With Hereditary Angioedema: Results From the Phase 3 SPRING Study.J Allergy Clin Immunol Pract2024
38009241A phase 2 open-label extension study of prekallikrein inhibition with donidalorsen for hereditary angioedema.Allergy2024
36868261Efficacy and safety of garadacimab, a factor XIIa inhibitor for hereditary angioedema prevention (VANGUARD): a global, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.Lancet2023
38082409Patient outcomes associated with subcutaneous C1INH prophylaxis for hereditary angioedema: a retrospective analysis.Allergy Asthma Clin Immunol2023
37746795Evaluation of patient-reported outcome measures for on-demand treatment of hereditary angioedema attacks and design of KONFIDENT, a phase 3 trial of sebetralstat.Clin Transl Allergy2023
37028510Long-term lanadelumab treatment improves health-related quality of life in patients with hereditary angioedema.Ann Allergy Asthma Immunol2023
36774155An investigational oral plasma kallikrein inhibitor for on-demand treatment of hereditary angioedema: a two-part, randomised, double-blind, placebo-controlled, crossover phase 2 trial.Lancet2023
34287942Long-term prevention of hereditary angioedema attacks with lanadelumab: The HELP OLE Study.Allergy2022
35831891Considerations in the management of hereditary angioedema due to C1-INH deficiency in women of childbearing age.Allergy Asthma Clin Immunol2022
35497649The international WAO/EAACI guideline for the management of hereditary angioedema - The 2021 revision and update.World Allergy Organ J2022
36057583Correction: Considerations in the management of hereditary angioedema due to C1-INH deficiency in women of childbearing age.Allergy Asthma Clin Immunol2022
35944615Efficacy, safety and pharmacokinetics of a new 10% normal human immunoglobulin for intravenous infusion, BT595, in children and adults with primary immunodeficiency disease.Vox Sang2022
35219377Prophylactic use of an anti-activated factor XII monoclonal antibody, garadacimab, for patients with C1-esterase inhibitor-deficient hereditary angioedema: a randomised, double-blind, placebo-controlled, phase 2 trial.Lancet2022
35294812Inhibition of Prekallikrein for Hereditary Angioedema.N Engl J Med2022
34753535Evaluation of the ocular safety associated with the exhalation delivery system with fluticasone.Allergy Asthma Proc2022
33098856Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial.J Allergy Clin Immunol2021
33866032Randomized Trial of the Efficacy and Safety of Berotralstat (BCX7353) as an Oral Prophylactic Therapy for Hereditary Angioedema: Results of APeX-2 Through 48 Weeks (Part 2).J Allergy Clin Immunol Pract2021
34879971Preventive Treatment of Hereditary Angioedema: A Review of Phase III Clinical Trial Data for Subcutaneous C1 Inhibitor and Relevance for Patient Management.Clin Ther2021
34176500Letting the patients speak: an in-depth, qualitative research-based investigation of factors relevant to health-related quality of life in real-world patients with hereditary angioedema using subcutaneous C1 inhibitor replacement therapy.Allergy Asthma Clin Immunol2021
34112472Triggers of Exacerbation in Chronic Urticaria and Recurrent Angioedema-Prevalence and Relevance.J Allergy Clin Immunol Pract2021
34048855Consensus on treatment goals in hereditary angioedema: A global Delphi initiative.J Allergy Clin Immunol2021
34305948Efficacy, Safety and Tolerability of a New 10% Intravenous Immunoglobulin for the Treatment of Primary Immunodeficiencies.Front Immunol2021
33258114Impact of lanadelumab on health-related quality of life in patients with hereditary angioedema in the HELP study.Allergy2021
32452549Lanadelumab demonstrates rapid and sustained prevention of hereditary angioedema attacks.Allergy2020
33109318Hereditary angioedema: Epidemiology and burden of disease.Allergy Asthma Proc2020
32248571Definition, aims, and implementation of GA<sup>2</sup> LEN/HAEi Angioedema Centers of Reference and Excellence.Allergy2020
32534150Association Between Self-Reported Dental Hygiene Practices and Dental Procedure-Related Recurrent Angioedema Attacks in HAE Subjects: A Multicenter Survey.J Allergy Clin Immunol Pract2020
30660873Treatment effect of switching from intravenous to subcutaneous C1-inhibitor for prevention of hereditary angioedema attacks: COMPACT subgroup findings.J Allergy Clin Immunol Pract2019
31485239Subcutaneous C1 inhibitor for prevention of attacks of hereditary angioedema: additional outcomes and subgroup analysis of a placebo-controlled randomized study.Allergy Asthma Clin Immunol2019
31621458Immune globulin subcutaneous, human - klhw 20% for primary humoral immunodeficiency: an open-label, Phase III study.Immunotherapy2019
30772477Long-Term Outcomes with Subcutaneous C1-Inhibitor Replacement Therapy for Prevention of Hereditary Angioedema Attacks.J Allergy Clin Immunol Pract2019
31170541Safety of recombinant human C1 esterase inhibitor for hereditary angioedema attacks during pregnancy.J Allergy Clin Immunol Pract2019
30682573Fixed-Dose Subcutaneous C1-Inhibitor Liquid for Prophylactic Treatment of C1-INH-HAE: SAHARA Randomized Study.J Allergy Clin Immunol Pract2019
30550806Development of a health-related quality of life instrument for patients with hereditary angioedema living in the United States.J Allergy Clin Immunol Pract2019
30539362Lanadelumab for the Prophylactic Treatment of Hereditary Angioedema with C1 Inhibitor Deficiency: A Review of Preclinical and Phase I Studies.BioDrugs2019
29318628The international WAO/EAACI guideline for the management of hereditary angioedema-The 2017 revision and update.Allergy2018
29998524Population pharmacokinetics of subcutaneous C1-inhibitor for prevention of attacks in patients with hereditary angioedema.Clin Exp Allergy2018
30132644Current and emerging therapies to prevent hereditary angioedema attacks.Am J Manag Care2018
30056152Long-term prophylaxis therapy in patients with hereditary angioedema with C1 inhibitor deficiency.Ann Allergy Asthma Immunol2018
30480729Effect of Lanadelumab Compared With Placebo on Prevention of Hereditary Angioedema Attacks: A Randomized Clinical Trial.JAMA2018
30534402Training patients for self-administration of a new subcutaneous C1-inhibitor concentrate for hereditary angioedema.Nurs Open2018
29503818Hereditary Angioedema: The Economics of Treatment of an Orphan Disease.Front Med (Lausanne)2018
29391286Health-Related Quality of Life with Subcutaneous C1-Inhibitor for Prevention of Attacks of Hereditary Angioedema.J Allergy Clin Immunol Pract2018
29669666Hereditary angioedema from the patient's perspective: A follow-up patient survey.Allergy Asthma Proc2018
29688579Evaluation of avoralstat, an oral kallikrein inhibitor, in a Phase 3 hereditary angioedema prophylaxis trial: The OPuS-2 study.Allergy2018
27865714Short-term prophylactic use of C1-inhibitor concentrate in hereditary angioedema: Findings from an international patient registry.Ann Allergy Asthma Immunol2017
28225674Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis.N Engl J Med2017
28381322Efficacy and safety of an intravenous C1-inhibitor concentrate for long-term prophylaxis in hereditary angioedema.Allergy Rhinol (Providence)2017
28328347Prevention of Hereditary Angioedema Attacks with a Subcutaneous C1 Inhibitor.N Engl J Med2017
28286153Safety of C1-inhibitor concentrate use for hereditary angioedema in pediatric patients.J Allergy Clin Immunol Pract2017
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Collaborators

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University of Cincinnati College of Medicine, and Bernstein Clinical Research Center
Co-authored papers 44
Penn State University
Co-authored papers 39
Icahn School of Medicine at Mount Sinai
Co-authored papers 28
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Co-authored papers 28
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Co-authored papers 25
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Co-authored papers 3
Howard Levy Consulting LLC
Co-authored papers 2
University of Wisconsin School of Medicine and Public Health
Co-authored papers 2
Massachusetts General Hospital, Harvard Medical School
Co-authored papers 1
Mayo Clinic College of Medicine and Science
Co-authored papers 1
Duke University
Co-authored papers 1
University of Cincinnati College of Medicine
Co-authored papers 1
Wake Forest School of Medicine
Co-authored papers 1
SUNY-Downstate Medical Center/Kings County Hospital Center
Co-authored papers 1
and Clinical Center (GRECC), Tennessee Valley Healthcare System
Co-authored papers 1
Henry Ford Hospital System
Co-authored papers 1
American College of Emergency Physicians
Co-authored papers 1
Co-authored papers 1
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 1
Drexel University
Co-authored papers 1
Vanderbilt University School of Medicine
Co-authored papers 1
Precision Immunology Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
UT Southwestern Medical Center
Co-authored papers 1