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| 36744494 | Dysregulated Smooth Muscle Cell BMPR2-ARRB2 Axis Causes Pulmonary Hypertension. | Circ Res | 2023 |
| 37392518 | Metabolic reprogramming, oxidative stress, and pulmonary hypertension. | Redox Biol | 2023 |
| 35696338 | Endogenous Retroviral Elements Generate Pathologic Neutrophils in Pulmonary Arterial Hypertension. | Am J Respir Crit Care Med | 2022 |
| 35680894 | Evolutionary action of mutations reveals antimicrobial resistance genes in Escherichia coli. | Nat Commun | 2022 |
| 35637192 | A cancer-associated RNA polymerase III identity drives robust transcription and expression of snaR-A noncoding RNA. | Nat Commun | 2022 |
| 33322916 | PPARγ-p53-Mediated Vasculoregenerative Program to Reverse Pulmonary Hypertension. | Circ Res | 2021 |
| 33764154 | ALDH1A3 Coordinates Metabolism With Gene Regulation in Pulmonary Arterial Hypertension. | Circulation | 2021 |
| 34185707 | Monocyte-released HERV-K dUTPase engages TLR4 and MCAM causing endothelial mesenchymal transition. | JCI Insight | 2021 |
| 34043002 | Identification of evolutionarily stable functional and immunogenic sites across the SARS-CoV-2 proteome and greater coronavirus family. | Bioinformatics | 2021 |
| 33106800 | Identification of evolutionarily stable functional and immunogenic sites across the SARS-CoV-2 proteome and the greater coronavirus family. | Res Sq | 2021 |
| 30699358 | PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis. | Cell Rep | 2019 |
| 31119679 | Personalized Metabolomics. | Methods Mol Biol | 2019 |
| 30416039 | Defining a Canonical Ligand-Binding Pocket in the Orphan Nuclear Receptor Nurr1. | Structure | 2019 |
| 29884781 | CRISPR-FRT targets shared sites in a knock-out collection for off-the-shelf genome editing. | Nat Commun | 2018 |
| 28890360 | Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA. | Structure | 2017 |
| 28528776 | Structural Basis of TPR-Mediated Oligomerization and Activation of Oncogenic Fusion Kinases. | Structure | 2017 |
| 26740599 | PPARγ Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose Tissue. | Diabetes | 2016 |
| 27391757 | Cooperativity of Negative Autoregulation Confers Increased Mutational Robustness. | Phys Rev Lett | 2016 |
| 27422345 | PPARG Post-translational Modifications Regulate Bone Formation and Bone Resorption. | EBioMedicine | 2016 |
| 26068133 | Pharmacological repression of PPARγ promotes osteogenesis. | Nat Commun | 2015 |
| 26451138 | Identification of Bexarotene as a PPARγ Antagonist with HDX. | PPAR Res | 2015 |
| 26585234 | Specific TP53 Mutants Overrepresented in Ovarian Cancer Impact CNV, TP53 Activity, Responses to Nutlin-3a, and Cell Survival. | Neoplasia | 2015 |
| 26289479 | Structural mechanism for signal transduction in RXR nuclear receptor heterodimers. | Nat Commun | 2015 |
| 26396687 | Design, Synthesis, and Biological Evaluation of Indole Biphenylcarboxylic Acids as PPARγ Antagonists. | ACS Med Chem Lett | 2015 |
| 24440037 | The therapeutic potential of nuclear receptor modulators for treatment of metabolic disorders: PPARγ, RORs, and Rev-erbs. | Cell Metab | 2014 |
| 25179005 | HDX-MS guided drug discovery: small molecules and biopharmaceuticals. | Curr Opin Struct Biol | 2014 |
| 24910431 | Negative feedback in genetic circuits confers evolutionary resilience and capacitance. | Cell Rep | 2014 |
| 24878423 | Prediction and redesign of protein-protein interactions. | Prog Biophys Mol Biol | 2014 |
| 24705063 | An alternate binding site for PPARγ ligands. | Nat Commun | 2014 |
| 24021383 | Accounting for epistatic interactions improves the functional analysis of protein structures. | Bioinformatics | 2013 |
| 22692830 | HDX workbench: software for the analysis of H/D exchange MS data. | J Am Soc Mass Spectrom | 2012 |
| 21912525 | Separation of recombination and SOS response in Escherichia coli RecA suggests LexA interaction sites. | PLoS Genet | 2011 |
| 21892191 | Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation. | Nature | 2011 |
| 19913036 | Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain. | J Mol Biol | 2010 |
| 20836087 | The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu. | Protein Sci | 2010 |
| 20944232 | Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944231 | Conformational changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas campestris pv. campestris. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944230 | Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core domain and an auxiliary C-terminal treble-clef zinc finger. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944229 | Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944228 | The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944225 | Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944224 | Structure of Bacteroides thetaiotaomicron BT2081 at 2.05⿿ÿ resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944223 | A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2⿿ÿ resolution. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944222 | Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944221 | The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944219 | The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944218 | Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944217 | Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944214 | Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |
| 20944213 | The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2010 |