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Author Details

Charles J Sherr
St. Jude Children's Research Hospital
1968
287
106
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34478658Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.Cell2021
32234521Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.Cell2020
30815226Sexually dimorphic tumor suppression by small mitochondrial <i>Arf</i>.Oncotarget2019
31831659Surprising regulation of cell cycle entry.Science2019
30573629NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination.Science2018
30214680Acquired palbociclib resistance in KRAS-mutant lung cancer.Oncotarget2018
29880921Mouse medulloblastoma driven by CRISPR activation of cellular Myc.Sci Rep2018
28652370Small mitochondrial Arf (smArf) protein corrects p53-independent developmental defects of <i>Arf</i> tumor suppressor-deficient mice.Proc Natl Acad Sci U S A2017
28329683Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma.Cell Rep2017
27959598A New Cell-Cycle Target in Cancer - Inhibiting Cyclin D-Dependent Kinases 4 and 6.N Engl J Med2016
26658964Targeting CDK4 and CDK6: From Discovery to Therapy.Cancer Discov2016
25499760Janus kinase inhibition by ruxolitinib extends dasatinib- and dexamethasone-induced remissions in a mouse model of Ph+ ALL.Blood2015
26105537Forging a signature of in vivo senescence.Nat Rev Cancer2015
24710003Host thiopurine methyltransferase status affects mercaptopurine antileukemic effectiveness in a murine model.Pharmacogenet Genomics2014
25128497CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma.Genes Dev2014
24567370Simultaneous gene editing by injection of mRNAs encoding transcription activator-like effector nucleases into mouse zygotes.Mol Cell Biol2014
23178376Epigenetic regulation of the Ink4a-Arf (Cdkn2a) tumor suppressor locus in the initiation and progression of Notch1-driven T cell acute lymphoblastic leukemia.Exp Hematol2013
23487795Arf tumor suppressor and miR-205 regulate cell adhesion and formation of extraembryonic endoderm from pluripotent stem cells.Proc Natl Acad Sci U S A2013
23153837How politics trumped peer review at Texas cancer institute.BMJ2012
22960768Ink4-Arf locus in cancer and aging.Wiley Interdiscip Rev Dev Biol2012
21263154Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome-positive acute lymphoblastic leukemia.Blood2011
21811412Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells.PLoS Genet2011
21427293Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies.Blood2011
20009580Developmental strategies for evasion of Arf tumor suppression.Cell Cycle2010
20516124Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells.Cancer Res2010
19147535Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma.Mol Cancer Res2009
19759355Stage-specific Arf tumor suppression in Notch1-induced T-cell acute lymphoblastic leukemia.Blood2009
19339492Transient expression of the Arf tumor suppressor during male germ cell and eye development in Arf-Cre reporter mice.Proc Natl Acad Sci U S A2009
19494829Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf.EMBO J2009
18418387Hzf regulates adipogenesis through translational control of C/EBPalpha.EMBO J2008
18948745Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3.Cell Cycle2008
19029828Differential post-transcriptional regulation of two Ink4 proteins, p18 Ink4c and p19 Ink4d.Cell Cycle2008
19028987The INK4-ARF (CDKN2A/B) locus in hematopoiesis and BCR-ABL-induced leukemias.Cold Spring Harb Symp Quant Biol2008
18574466BCR-ABL and CDKN2A: a dropped connection.Nat Rev Cancer2008
18519632Failure of CDKN2A/B (INK4A/B-ARF)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL.Genes Dev2008
16968893Regulation of the Arf tumor suppressor in Emicro-Myc transgenic mice: longitudinal study of Myc-induced lymphomagenesis.Blood2007
17761812Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia.Genes Dev2007
17695724The ARF tumor suppressor in acute leukemias: insights from mouse models of Bcr-Abl-induced acute lymphoblastic leukemia.Adv Exp Med Biol2007
17363588Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors.Cancer Res2007
16382142Hzf, a p53-responsive gene, regulates maintenance of the G2 phase checkpoint induced by DNA damage.Mol Cell Biol2006
16713573Autophagy by ARF: a short story.Mol Cell2006
16864777N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development.Proc Natl Acad Sci U S A2006
16915296Divorcing ARF and p53: an unsettled case.Nat Rev Cancer2006
16479172The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma.Cell Cycle2006
16671360Ubiquitination of, and sumoylation by, the Arf tumor suppressor.Isr Med Assoc J2006
16618932Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia.Proc Natl Acad Sci U S A2006
15601844Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor.Mol Cell Biol2005
16869746p53-Dependent and -independent functions of the Arf tumor suppressor.Cold Spring Harb Symp Quant Biol2005
16205118Myeloid leukemia-associated nucleophosmin mutants perturb p53-dependent and independent activities of the Arf tumor suppressor protein.Cell Cycle2005
16222716Tbx3, the ulnar-mammary syndrome gene, and Tbx2 interact in mammary gland development through a p19Arf/p53-independent pathway.Dev Dyn2005
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Collaborators

St. Jude Children's Research Hospital
Co-authored papers 96
St. Jude Children's Research Hospital
Co-authored papers 26
Dana-Farber Cancer Institute
Co-authored papers 15
Mayo Clinic College of Medicine
Co-authored papers 13
Kaohsiung Chang Gung Memorial Hospital
Co-authored papers 11
Genentech Inc.
Co-authored papers 10
St. Jude Children's Research Hospital
Co-authored papers 10
Case Western Reserve University School of Medicine
Co-authored papers 7
Washington University School of Medicine
Co-authored papers 7
Co-authored papers 6
Fred Hutchinson Cancer Research Center
Co-authored papers 6
Institut Curie, PSL Research University, CNRS UMR, INSERM
Co-authored papers 4
Co-authored papers 4
St. Jude Children's Research Hospital
Co-authored papers 3
AbbVie Inc.
Co-authored papers 3
Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 2
St. Jude Children's Research Hospital
Co-authored papers 2
St. Jude Children's Research Hospital
Co-authored papers 2
St. Jude Children's Research Hospital
Co-authored papers 2
Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 2
Institute of Pathology, Kings County Hospital Center
Co-authored papers 2
Wilmer Eye Institute, Johns Hopkins Medical Institutions
Co-authored papers 2
Departments of Oncology. St. Jude Children's Research Hospital
Co-authored papers 2
Departments of Pharmaceutical Sciences.
Co-authored papers 2
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Hollings Cancer Center, Medical University of South Carolina
Co-authored papers 1
University of California los angeles
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1