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Author Details

Sumit K Chanda
The Scripps Research Institute
2001
104
42
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36803114Activation of the Interferon Pathway in Trophoblast Cells Productively Infected with SARS-CoV-2.Stem Cells Dev2023
37758692Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets.Nat Commun2023
37720034Live imaging of the airway epithelium reveals that mucociliary clearance modulates SARS-CoV-2 spread.Res Sq2023
36804936Identification of global inhibitors of cellular glycosylation.Nat Commun2023
35095847NFAM1 Promotes Pro-Inflammatory Cytokine Production in Mouse and Human Monocytes.Front Immunol2022
35809572Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA.Mol Cell2022
35766385Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity.ACS Infect Dis2022
35502318Synthetic lethality-based prediction of anti-SARS-CoV-2 targets.iScience2022
36532738Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex.Front Pharmacol2022
36327326SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir.PLoS Biol2022
36197970Common and species-specific molecular signatures, networks, and regulators of influenza virus infection in mice, ferrets, and humans.Sci Adv2022
33440148MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells.Cell Rep2021
33791697The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection.bioRxiv2021
33532779Genome-scale metabolic modeling reveals SARS-CoV-2-induced metabolic changes and antiviral targets.bioRxiv2021
33727703Clofazimine broadly inhibits coronaviruses including SARS-CoV-2.Nature2021
33930332Functional landscape of SARS-CoV-2 cellular restriction.Mol Cell2021
33836156TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.Cell2021
35003140Development of an <i>In Vivo</i> Probe to Track SARS-CoV-2 Infection in Rhesus Macaques.Front Immunol2021
34709707Genome-scale metabolic modeling reveals SARS-CoV-2-induced metabolic changes and antiviral targets.Mol Syst Biol2021
34556855Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy.Nat Microbiol2021
34468177The Compound SBI-0090799 Inhibits Zika Virus Infection by Blocking <i>De Novo</i> Formation of the Membranous Replication Compartment.J Virol2021
34843601A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor.PLoS Pathog2021
34545363Synthetic lethality-based prediction of anti-SARS-CoV-2 targets.bioRxiv2021
32511357A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals.bioRxiv2020
31968566Sensor Sensibility-HIV-1 and the Innate Immune Response.Cells2020
31776276Viral Determinants in H5N1 Influenza A Virus Enable Productive Infection of HeLa Cells.J Virol2020
33052331Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters.Res Sq2020
33024967Functional Landscape of SARS-CoV-2 Cellular Restriction.bioRxiv2020
33299999Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.bioRxiv2020
33097660SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling.Proc Natl Acad Sci U S A2020
33205060Pharmacological Activation of Non-canonical NF-κB Signaling Activates Latent HIV-1 Reservoirs In Vivo.Cell Rep Med2020
32882949The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription.Cells2020
32707573Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.Nature2020
32415096mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1.Nat Commun2020
30691001HIV-1 Fusion with CD4+ T cells Is Promoted by Proteins Involved in Endocytosis and Intracellular Membrane Trafficking.Viruses2019
30944313Metascape provides a biologist-oriented resource for the analysis of systems-level datasets.Nat Commun2019
30717826HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses.Elife2019
30716099The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate.PLoS One2019
30397075SNW1, a Novel Transcriptional Regulator of the NF-κB Pathway.Mol Cell Biol2019
29268608Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein.ACS Infect Dis2018
29490283Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu.Cell Rep2018
28819179Identification of Polo-like kinases as potential novel drug targets for influenza A virus.Sci Rep2017
28106169Inhibition of NUCKS Facilitates Corneal Recovery Following Alkali Burn.Sci Rep2017
28248290Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation.Nat Microbiol2017
28475896The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity.Cell2017
27078069NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses.Cell Host Microbe2016
26609934Interferon but not MxB inhibits foamy retroviruses.Virology2016
27832591A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export.Cell Host Microbe2016
25728676Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy.Oncogene2015
26355217BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.Cell Host Microbe2015
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Collaborators

Paul D De Jesus
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Co-authored papers 31
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Co-authored papers 26
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Co-authored papers 21
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Co-authored papers 19
Renate K??nig
Paul-Ehrlich-Institut
Co-authored papers 16
Xin Yin
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 16
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Genomics Institute of the Novartis Research Foundation
Co-authored papers 15
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Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 14
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 13
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Sanford Burnham Prebys Medical Discovery Institute
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Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
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University of California los angeles
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Roche Pharma
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Loren Miraglia
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Trey Ideker (CM4AI)
University of California San Diego
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Christopher Benner
Michigan State University College of Human Medicine
Co-authored papers 9
Randy A Albrecht
Icahn School of Medicine at Mount Sinai
Co-authored papers 8
Jeremy S Caldwell
Sirna Therapeutics a former subsidiary of Merck & Co., Inc.
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Ariel Rodriguez-Frandsen
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 8
Megan L Shaw
Icahn School of Medicine at Mount Sinai
Co-authored papers 8
Sunnie M Yoh
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Co-authored papers 8
Stephen Soonthornvacharin
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Lisa Miorin
Icahn School of Medicine at Mount Sinai
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Frederic D Bushman
Perelman School of Medicine, University of Pennsylvania
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