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Author Details

Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
1976
1035
172
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36054930A distinct pattern of growth and RAC1 signaling in melanoma brain metastasis cells.Neuro Oncol2023
36044040In vivo functional characterization of EGFR variants identifies novel drivers of glioblastoma.Neuro Oncol2023
36265133Landscape of MicroRNA Regulatory Network Architecture and Functional Rerouting in Cancer.Cancer Res2023
36054930A distinct pattern of growth and RAC1 signaling in melanoma brain metastasis cells.Neuro Oncol2023
37596261Irreversible HER2 inhibitors overcome resistance to the RSL3 ferroptosis inducer in non-HER2 amplified luminal breast cancer.Cell Death Dis2023
37589839Identifying homologous recombination deficiency in breast cancer: genomic instability score distributions differ among breast cancer subtypes.Breast Cancer Res Treat2023
37909041Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins.Cell Rep Med2023
37645765MIM-CyCIF: Masked Imaging Modeling for Enhancing Cyclic Immunofluorescence (CyCIF) with Panel Reduction and Imputation.bioRxiv2023
37205498Systematic Pan-cancer Functional Inference and Validation of Hyper, Hypo and Neomorphic Mutations.bioRxiv2023
37137501The Breast Cancer Proteome and Precision Oncology.Cold Spring Harb Perspect Med2023
37454202Actionability classification of variants of unknown significance correlates with functional effect.NPJ Precis Oncol2023
37072347BRD4 inhibition impairs DNA mismatch repair, induces mismatch repair mutation signatures and creates therapeutic vulnerability to immune checkpoint blockade in MMR-proficient tumors.J Immunother Cancer2023
36871660Multiplatform Analysis of Intratumoral PTEN Heterogeneity in Melanoma.J Invest Dermatol2023
36797475Stiff matrix induces exosome secretion to promote tumour growth.Nat Cell Biol2023
36993424Supervised learning of high-confidence phenotypic subpopulations from single-cell data.bioRxiv2023
36672243Panobinostat Induced Spatial In Situ Biomarkers Predictive of Anti-PD-1 Efficacy in Mouse Mammary Carcinoma.Cells2023
36726166PMCA inhibition reverses drug resistance in clinically refractory cancer patient-derived models.BMC Med2023
37542044Single-cell trajectory analysis reveals a CD9 positive state to contribute to exit from stem cell-like and embryonic diapause states and transit to drug-resistant states.Cell Death Discov2023
37596261Irreversible HER2 inhibitors overcome resistance to the RSL3 ferroptosis inducer in non-HER2 amplified luminal breast cancer.Cell Death Dis2023
37909041Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins.Cell Rep Med2023
37589839Identifying homologous recombination deficiency in breast cancer: genomic instability score distributions differ among breast cancer subtypes.Breast Cancer Res Treat2023
37542044Single-cell trajectory analysis reveals a CD9 positive state to contribute to exit from stem cell-like and embryonic diapause states and transit to drug-resistant states.Cell Death Discov2023
37645765MIM-CyCIF: Masked Imaging Modeling for Enhancing Cyclic Immunofluorescence (CyCIF) with Panel Reduction and Imputation.bioRxiv2023
36993424Supervised learning of high-confidence phenotypic subpopulations from single-cell data.bioRxiv2023
37454202Actionability classification of variants of unknown significance correlates with functional effect.NPJ Precis Oncol2023
37205498Systematic Pan-cancer Functional Inference and Validation of Hyper, Hypo and Neomorphic Mutations.bioRxiv2023
37072347BRD4 inhibition impairs DNA mismatch repair, induces mismatch repair mutation signatures and creates therapeutic vulnerability to immune checkpoint blockade in MMR-proficient tumors.J Immunother Cancer2023
37137501The Breast Cancer Proteome and Precision Oncology.Cold Spring Harb Perspect Med2023
36871660Multiplatform Analysis of Intratumoral PTEN Heterogeneity in Melanoma.J Invest Dermatol2023
36672243Panobinostat Induced Spatial In Situ Biomarkers Predictive of Anti-PD-1 Efficacy in Mouse Mammary Carcinoma.Cells2023
36797475Stiff matrix induces exosome secretion to promote tumour growth.Nat Cell Biol2023
36726166PMCA inhibition reverses drug resistance in clinically refractory cancer patient-derived models.BMC Med2023
36044040In vivo functional characterization of EGFR variants identifies novel drivers of glioblastoma.Neuro Oncol2023
36265133Landscape of MicroRNA Regulatory Network Architecture and Functional Rerouting in Cancer.Cancer Res2023
33950412Precision oncology for breast cancer through clinical trials.Clin Exp Metastasis2022
36309506Proteo-genomic characterization of virus-associated liver cancers reveals potential subtypes and therapeutic targets.Nat Commun2022
35835783HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8<sup>+</sup> T-cell infiltration into tumors.Nat Commun2022
36209972Lysophosphatidic acid-induced amphiregulin secretion by cancer-associated fibroblasts augments cancer cell invasion.Cancer Lett2022
36207580A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses.Commun Biol2022
35871223Development of a nanoparticle-based immunotherapy targeting PD-L1 and PLK1 for lung cancer treatment.Nat Commun2022
35800377Ovarian cancer recurrence: "is the definition of platinum resistance modified by PARP inhibitors and other intervening treatments?"Cancer Drug Resist2022
35619328Inhibiting the IRE1α Axis of the Unfolded Protein Response Enhances the Antitumor Effect of AZD1775 in TP53 Mutant Ovarian Cancer.Adv Sci (Weinh)2022
36205581RPPA SPACE: an R package for normalization and quantitation of Reverse-Phase Protein Array data.Bioinformatics2022
35483739Adjuvant treatment in early-stage endometrial cancer: context-dependent impact of somatic CTNNB1 mutation on recurrence-free survival.Int J Gynecol Cancer2022
36194131IMP1/IGF2BP1 in human colorectal cancer extracellular vesicles.Am J Physiol Gastrointest Liver Physiol2022
35788566A multiplex implantable microdevice assay identifies synergistic combinations of cancer immunotherapies and conventional drugs.Nat Biotechnol2022
35921524Identification of a Molecularly-Defined Subset of Breast and Ovarian Cancer Models that Respond to WEE1 or ATR Inhibition, Overcoming PARP Inhibitor Resistance.Clin Cancer Res2022
35538088Identification of biomarkers of response to preoperative talazoparib monotherapy in treatment naïve gBRCA+ breast cancers.NPJ Breast Cancer2022
35852417Biomolecular Condensation: A New Phase in Cancer Research.Cancer Discov2022
35466854Characterization of anticancer drug resistance by reverse-phase protein array: new targets and strategies.Expert Rev Proteomics2022
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Gao Zhang
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Kevin R Coombes
Medical College of Georgia
Co-authored papers 20
Shiaw-Yih Lin
The University of Texas MD Anderson Cancer Center
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Prahlad T Ram
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Alexander J Lazar
The University of Texas MD Anderson Cancer Center
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Andrew D Cherniack
Dana-Farber Cancer Institute
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Laura M Heiser
Oregon Health Sciences University
Co-authored papers 16
Rosemarie Schmandt
The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Co-authored papers 16
Jennifer R Grandis
University of California san francisco
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Roel G W Verhaak
Yale School of Medicine
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Release 1.2