Author details

Full Name

Lennart C Karssen

Affiliation

ORCID

Career Start Year

2011

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37373966	Development and Replication of a Genome-Wide Polygenic Risk Score for Chronic Back Pain.		2023
32521004	Replication of 15 loci involved in human plasma protein N-glycosylation in 4802 samples from four cohorts.	Glycobiology	2021
33245779	PheLiGe: an interactive database of billions of human genotype-phenotype associations.	Nucleic Acids Research	2021
35088001	The GWAS-MAP platform for aggregation of results of genome-wide association studies and the GWAS-MAP\|homo database of 70 billion genetic associations of human traits.	Vavilovskii Zhurnal Genetiki i Selektsii	2020
30747904	Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individuals.	Pain	2019
30261039	Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain.	PLoS Genet	2018
29981899	Plasma N-glycome composition associates with chronic low back pain.	Biochimica et Biophysica Acta - General Subjects	2018
28513607	Variants in TTC25 affect autistic trait in patients with autism spectrum disorder and general population.	Eur J Hum Genet	2017
28566273	An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.	Diabetes	2017
27561104	Non-additive genome-wide association scan reveals a new gene associated with habitual coffee consumption.	Sci Rep	2016
27347381	The GenABEL Project for statistical genomics.	F1000Res	2016
27059780	CollapsABEL: an R library for detecting compound heterozygote alleles in genome-wide association studies.	BMC Bioinformatics	2016
27129595	A Genome-Wide Association Study in isolated populations reveals new genes associated to common food likings.	Rev Endocr Metab Disord	2016
27798002	'Omics' biomarkers associated with chronic low back pain: protocol of a retrospective longitudinal study.	BMJ Open	2016
26551672	Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.	Nat Genet	2015
25883321	Characteristics of de novo structural changes in the human genome.	Genome Res	2015
25751400	Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels.	Nat Commun	2015
25367360	Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.	Hum Genet	2015
25569235	Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses.	PLoS Genet	2015
25961943	The impact of low-frequency and rare variants on lipid levels.	Nat Genet	2015
25758996	Genome-wide association analysis on five isolated populations identifies variants of the HLA-DOA gene associated with white wine liking.	Eur J Hum Genet	2015
26226460	Population-specific genotype imputations using minimac or IMPUTE2.	Nat Protoc	2015
26132169	Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.	PLoS Genet	2015
25241763	Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.	Nat Commun	2014
25329471	The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels.	PLoS One	2014
23979607	Genome-wide analyses of borderline personality features.	Mol Psychiatry	2014
23714750	The Genome of the Netherlands: design, and project goals.	Eur J Hum Genet	2014
25233373	Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci.	PLoS One	2014
25173106	Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.	Nat Genet	2014
24896149	Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'.	Eur J Hum Genet	2014
24647340	Association analysis of bitter receptor genes in five isolated populations identifies a significant correlation between TAS2R43 variants and coffee liking.	PLoS One	2014
23343465	Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes.	BMC Med Genet	2013
23824655	The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.	PLoS Med	2013
23535734	Identification of seven loci affecting mean telomere length and their association with disease.	Nat Genet	2013
23474815	Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error.	Hum Mol Genet	2013
22359512	Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.	PLoS Genet	2012
22643180	Analytical and simulation methods for estimating the potential predictive ability of genetic profiling: a comparison of methods and results.	European Journal of Human Genetics	2012
22665138	Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium.	Hum Genet	2012
22028671	A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.	PLoS Genet	2011