Author details

Full Name

James A Knowles

Affiliation

ORCID

Career Start Year

1982

Papers

205

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37034711	Cultured Mesenchymal Cells from Nasal Turbinate as a Cellular Model of the Neurodevelopmental Component of Schizophrenia Etiology.		2023
37895019	Cultured Mesenchymal Cells from Nasal Turbinate as a Cellular Model of the Neurodevelopmental Component of Schizophrenia Etiology.		2023
36940628	Prevalence and correlates of lifetime suicide attempt in obsessive-compulsive disorder with major depression.	J Psychiatr Res	2023
36538573	Study protocol of DIVERGE, the first genetic epidemiological study of major depressive disorder in Pakistan.		2023
34099189	Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.	Biol Psychiatry	2022
35396580	Mapping genomic loci implicates genes and synaptic biology in schizophrenia.	Nature	2022
35396579	Rare coding variants in ten genes confer substantial risk for schizophrenia.	Nature	2022
35048876	Characterisation of age and polarity at onset in bipolar disorder.	Br J Psychiatry	2021
35747302	What Have We Learned About the Genetics of Obsessive-Compulsive and Related Disorders in Recent Years?	Focus (Am Psychiatr Publ)	2021
34002096	Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.	Nat Genet	2021
33942911	Is Persistent Motor or Vocal Tic Disorder a Milder Form of Tourette Syndrome?	Mov Disord	2021
34183866	Exome sequencing in obsessive-compulsive disorder reveals a burden of rare damaging coding variants.	Nat Neurosci	2021
30087453	Examination of the shared genetic basis of anorexia nervosa and obsessive-compulsive disorder.	Mol Psychiatry	2020
32143829	Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia.	Biol Psychiatry	2020
32029778	Robust RNA-Seq of aRNA-amplified single cell material collected by patch clamp.	Scientific Reports	2020
31985533	Genes Implicated in Rare Congenital Inner Ear and Cochleovestibular Nerve Malformations.	Ear Hear	2020
32446006	Greater history of traumatic event exposure and PTSD associated with comorbid body dysmorphic disorder in a large OCD cohort.	Psychiatry Research	2020
31859455	General personality dimensions, impairment and treatment response in obsessive-compulsive disorder.	Personal Ment Health	2020
32709417	Transcriptional Profiling of Primate Central Nucleus of the Amygdala Neurons to Understand the Molecular Underpinnings of Early-Life Anxious Temperament.	Biological Psychiatry	2020
32561870	Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain.	Sci Data	2020
32780866	Recurrent Rare Copy Number Variants Increase Risk for Esotropia.	Invest Ophthalmol Vis Sci	2020
32502964	A CTGF-YAP Regulatory Pathway Is Essential for Angiogenesis and Barriergenesis in the Retina.	iScience	2020
31422797	Dorsal Amygdala Neurotrophin-3 Decreases Anxious Temperament in Primates.	Biological Psychiatry	2019
31595699	A de novo SIX1 variant in a patient with a rare nonsyndromic cochleovestibular nerve abnormality, cochlear hypoplasia, and bilateral sensorineural hearing loss.	Mol Genet Genomic Med	2019
29961565	Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.	Biol Psychiatry	2019
30818990	Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.	Am J Psychiatry	2019
30699873	Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry.	J Affect Disord	2019
31501410	Btbd3 expression regulates compulsive-like and exploratory behaviors in mice.	Translational Psychiatry	2019
31170001	Immune-Related Comorbidities in Childhood-Onset Obsessive Compulsive Disorder: Lifetime Prevalence in the Obsessive Compulsive Disorder Collaborative Genetics Association Study.	J Child Adolesc Psychopharmacol	2019
30686506	Contribution of Rare Copy Number Variants toÂ Bipolar Disorder Risk Is Limited to Schizoaffective Cases.	Biol Psychiatry	2019
30902966	Concordance of genetic variation that increases risk for tourette syndrome and that influences its underlying neurocircuitry.	Transl Psychiatry	2019
31003785	Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts.	Biol Psychiatry	2019
31535015	Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia.	Sci Adv	2019
29700475	Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.	Nat Genet	2018
30555922	Using 3D epigenomic maps of primary olfactory neuronal cells from living individuals to understand gene regulation.	Sci Adv	2018
29930110	Analysis of shared heritability in common disorders of the brain.	Science	2018
30545857	Comprehensive functional genomic resource and integrative model for the human brain.	Science	2018
30545854	Integrative functional genomic analysis of human brain development and neuropsychiatric risks.	Science	2018
29955957	De novo variants in GREB1L are associated with non-syndromic inner ear malformations and deafness.	Hum Genet	2018
29947313	Significant concordance of genetic variation that increases both the risk for obsessive-compulsive disorder and the volumes of the nucleus accumbens and putamen.	Br J Psychiatry	2018
29396406	Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability.	Scientific Reports	2018
29268152	Self-reported executive function and hoarding in adults with obsessive-compulsive disorder.	Compr Psychiatry	2018
29663135	When tractography meets tracer injections: a systematic study of trends and variation sources of diffusion-based connectivity.	Brain Struct Funct	2018
27869829	Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.	Nat Genet	2017
28350396	Genetic effects influencing risk for major depressive disorder in China and Europe.	Transl Psychiatry	2017
28641744	Polygenic risk score and heritability estimates reveals a genetic relationship between ASD and OCD.	Eur Neuropsychopharmacol	2017
28641109	Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome.	Neuron	2017
28386217	Genome Wide Association Study (GWAS) between Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD).	Front Mol Neurosci	2017
28671696	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	Nat Neurosci	2017
28800603	Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort.	PLoS ONE	2017