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Author Details

Richard Mitter
The Francis Crick Institute
2008
63
36
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36332625Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia.Cancer Cell2023
37683646DNA-directed termination of RNA polymerase II transcription.Mol Cell2023
37159667Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells.Cell Rep Methods2023
36662229B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice.J Exp Med2023
35334218Rostrocaudal patterning and neural crest differentiation of human pre-neural spinal cord progenitors in vitro.Stem Cell Reports2022
35425964Editor's Note: miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance.Cancer Res2022
36590686Elongation factor-specific capture of RNA polymerase II complexes.Cell Rep Methods2022
36121223An Important Role for RPRD1B in the Heat Shock Response.Mol Cell Biol2022
35042798Integrated genome and transcriptome analyses reveal the mechanism of genome instability in ataxia with oculomotor apraxia 2.Proc Natl Acad Sci U S A2022
35114099Heat shock induces premature transcript termination and reconfigures the human transcriptome.Mol Cell2022
33119032Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival.J Exp Med2021
34111399Translation stress and collided ribosomes are co-activators of cGAS.Mol Cell2021
34163038Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.Nat Cell Biol2021
34108662Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.Nat Cell Biol2021
32531245Evidence That STK19 Is Not an NRAS-dependent Melanoma Driver.Cell2020
31988092Greb1 is required for axial elongation and segmentation in vertebrate embryos.Biol Open2020
31915390Using TT<sub>chem</sub>-seq for profiling nascent transcription and measuring transcript elongation.Nat Protoc2020
32094115A single cell transcriptome atlas of the developing zebrafish hindbrain.Development2020
32142654Regulation of the RNAPII Pool Is Integral to the DNA Damage Response.Cell2020
30670056Correction to: Transcriptomes of microglia in experimental cerebral malaria in mice in the presence and absence of Type I Interferon signaling.BMC Res Notes2019
31519522Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability.Mol Cell2019
31104839SCAF4 and SCAF8, mRNA Anti-Terminator Proteins.Cell2019
29346117The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.J Clin Invest2018
30572937Transcriptomes of microglia in experimental cerebral malaria in mice in the presence and absence of Type I Interferon signaling.BMC Res Notes2018
29233846VE-Cadherin-Mediated Epigenetic Regulation of Endothelial Gene Expression.Circ Res2018
28961847Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters.Ann Oncol2017
28215706UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene.Cell2017
28445112Tracking the Evolution of Non-Small-Cell Lung Cancer.N Engl J Med2017
280926786-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.Oncogene2017
25804630The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis.Gut2016
27806305A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.Cell Rep2016
27798604Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours.Nat Cell Biol2016
26940869Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.Science2016
27042297Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.Cancer Metab2016
26883360Mutation of cancer driver MLL2 results in transcription stress and genome instability.Genes Dev2016
26823523Detection of ubiquitous and heterogeneous mutations in cell-free DNA from patients with early-stage non-small-cell lung cancer.Ann Oncol2016
25788261Stratifying risk of recurrence in stage II colorectal cancer using deregulated stromal and epithelial microRNAs.Oncotarget2015
25934693miR-19-Mediated Inhibition of Transglutaminase-2 Leads to Enhanced Invasion and Metastasis in Colorectal Cancer.Mol Cancer Res2015
26003801Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy.Cancer Discov2015
25619842SREBP maintains lipid biosynthesis and viability of cancer cells under lipid- and oxygen-deprived conditions and defines a gene signature associated with poor survival in glioblastoma multiforme.Oncogene2015
25716680Usp28 counteracts Fbw7 in intestinal homeostasis and cancer.Cancer Res2015
24836208Molecular profiling of the invasive tumor microenvironment in a 3-dimensional model of colorectal cancer cells and ex vivo fibroblasts.J Vis Exp2014
25301630Spatial and temporal diversity in genomic instability processes defines lung cancer evolution.Science2014
25003521Tracking genomic cancer evolution for precision medicine: the lung TRACERx study.PLoS Biol2014
24836610RECQL5 controls transcript elongation and suppresses genome instability associated with transcription stress.Cell2014
23118343Endogenous ribosomal protein L29 (RPL29): a newly identified regulator of angiogenesis in mice.Dis Model Mech2013
24095676HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress.Cell Stem Cell2013
23880823Characterisations of human prostate stem cells reveal deficiency in class I UGT enzymes as a novel mechanism for castration-resistant prostate cancer.Br J Cancer2013
23950211miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance.Cancer Res2013
22920255c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration.Neuron2012
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Collaborators

Jesper Q Svejstrup
Panum Institute, University of Copenhagen
Co-authored papers 16
Charles Swanton
Francis Crick Institute
Co-authored papers 8
Adrian L Harris
University of Oxford
Co-authored papers 3
Peter Van Loo
The Francis Crick Institute
Co-authored papers 2
Cristina Ivan
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Fiona Blackhall
The University of Manchester
Co-authored papers 2
Stefan C Dentro
Wellcome Sanger Institute
Co-authored papers 2
Jeroen A A Demmers
Erasmus Medical Center
Co-authored papers 2
John Le Quesne
Beatson Cancer Research Institute, University of Glasgow
Co-authored papers 2
Dean A Fennell
University of Leicester
Co-authored papers 2
Maria T Ocampo-Hafalla
The Francis Crick Institute
Co-authored papers 1
Levi A Garraway
Broad Institute of Harvard and MIT
Co-authored papers 1
Vardhman K Rakyan
The Blizard Institute, Queen Mary University of London
Co-authored papers 1
David A Waller
St Bartholomew's Hospital
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Eleni M Tomazou
St. Anna Children's Cancer Research Institute (CCRI)
Co-authored papers 1
Timothy A Chan
Cleveland Clinic.
Co-authored papers 1
Paolo Inglese
The Francis Crick Institute
Co-authored papers 1
Ajay A Vashisht
David Geffen School of Medicine, University of California los angeles
Co-authored papers 1
Luke A Selth
Adelaide Medical School, University of Adelaide
Co-authored papers 1
David A Moore
University College London Cancer Institute
Co-authored papers 1
Apostolos Nakas
University Hospitals of Leicester NHS Trust
Co-authored papers 1
Thierry Voet
KU Leuven Institute for Single Cell Omics (LISCO)
Co-authored papers 1
Peter J Campbell
Wellcome Sanger Institute
Co-authored papers 1
Eliezer M Van Allen
Dana-Farber Cancer Institute
Co-authored papers 1
Michael J O Wakelam
Co-authored papers 1
Enzo Medico
Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia (FPO) - IRCCS
Co-authored papers 1
David C Wedge
Manchester Cancer Research Centre, University of Manchester
Co-authored papers 1
Timothy T Harkins
NVIDIA Corporation
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Release 1.2