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Author Details

Yushen Du
University of California los angeles
2014
38
17
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36773549Synthesis and structure-activity optimization of 7-azaindoles containing aza-β-amino acids targeting the influenza PB2 subunit.Eur J Med Chem2023
37481436Martynoside rescues 5-fluorouracil-impaired ribosome biogenesis by stabilizing RPL27A.Sci Bull (Beijing)2023
37680460Structural characterization of an isocytosine-specific deaminase VCZ reveals its application potential in the anti-cancer therapy.iScience2023
37772870Deep mutational scanning of influenza A virus neuraminidase facilitates the identification of drug resistance mutations <i>in vivo</i>.mSystems2023
35247593Approaches for discovery of small-molecular antivirals targeting to influenza A virus PB2 subunit.Drug Discov Today2022
35013215Latency reversal plus natural killer cells diminish HIV reservoir in vivo.Nat Commun2022
34161773Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation.Cell Rep2021
33765584Ex vivo and in vivo chemoprotective activity and potential mechanism of Martynoside against 5-fluorouracil-induced bone marrow cytotoxicity.Biomed Pharmacother2021
33850042Quantifying the Evolutionary Constraints and Potential of Hepatitis C Virus NS5A Protein.mSystems2021
33727703Clofazimine broadly inhibits coronaviruses including SARS-CoV-2.Nature2021
34826321On-demand nanozyme signal enhancement at the push of a button for the improved detection of SARS-CoV-2 nucleocapsid protein in serum.Analyst2021
32415096mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1.Nat Commun2020
33377133Tracking HIV Rebound following Latency Reversal Using Barcoded HIV.Cell Rep Med2020
33085662Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease.PLoS Genet2020
33052331Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters.Res Sq2020
33292526Emerging roles of N6-methyladenosine (m<sup>6</sup>A) modification in breast cancer.Cell Biosci2020
29348231Genome-wide identification of interferon-sensitive mutations enables influenza vaccine design.Science2018
30075008Inhibition of murine herpesvirus-68 replication by IFN-gamma in macrophages is counteracted by the induction of SOCS1 expression.PLoS Pathog2018
29933437Emergence of Integrase Resistance Mutations During Initial Therapy Containing Dolutegravir.Clin Infect Dis2018
30227960High-Throughput Fitness Profiling of Zika Virus E Protein Reveals Different Roles for Glycosylation during Infection of Mammalian and Mosquito Cells.iScience2018
30311576Immunotherapy for EBV-Associated Nasopharyngeal Carcinoma.Crit Rev Oncog2018
27992877In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus.Nature2017
28159892Systematic identification of anti-interferon function on hepatitis C virus genome reveals p7 as an immune evasion protein.Proc Natl Acad Sci U S A2017
28441397Correction: Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality.PLoS Genet2017
29184023Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes.mBio2017
28515293Virus-Like Vesicles of Kaposi's Sarcoma-Associated Herpesvirus Activate Lytic Replication by Triggering Differentiation Signaling.J Virol2017
28860476Quantifying perinatal transmission of Hepatitis B viral quasispecies by tag linkage deep sequencing.Sci Rep2017
28787455HIV-1 epitopes presented by MHC class I types associated with superior immune containment of viremia have highly constrained fitness landscapes.PLoS Pathog2017
27926822Proteomic and phylogenetic coevolution analyses of pM79 and pM92 identify interactions with RNA polymerase II and delineate the murine cytomegalovirus late transcription complex.J Gen Virol2017
26754751Coupling high-throughput genetics with phylogenetic information reveals an epistatic interaction on the influenza A virus M segment.BMC Genomics2016
27832591A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export.Cell Host Microbe2016
27803181Annotating Protein Functional Residues by Coupling High-Throughput Fitness Profile and Homologous-Structure Analysis.mBio2016
26132554Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality.PLoS Genet2015
26561297MYC-induced reprogramming of glutamine catabolism supports optimal virus replication.Nat Commun2015
26364133High-resolution genetic profile of viral genomes: why it matters.Curr Opin Virol2015
24722365A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity.PLoS Pathog2014
24842159HIV-1 quasispecies delineation by tag linkage deep sequencing.PLoS One2014
25056896Kaposi's sarcoma-associated herpesvirus ORF18 and ORF30 are essential for late gene expression during lytic replication.J Virol2014
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Collaborators

Ren Sun
University of California los angeles
Co-authored papers 32
Ting-Ting Wu
Xinjiang Medical University Affiliated First Hospital
Co-authored papers 16
Tian-Hao Zhang
David Geffen School of Medicine, University of California los angeles
Co-authored papers 15
Danyang Gong
David Geffen School of Medicine, University of California los angeles
Co-authored papers 9
Kejun Tang
Women's Hospital, Zhejiang University
Co-authored papers 6
Mengying Hong
Co-authored papers 6
Lei Dai
Xiangya Hospital of Central South University
Co-authored papers 6
Christine A Olson
University of California los angeles
Co-authored papers 6
Xinmin Li
University of California los angeles
Co-authored papers 5
Sara Shu
University of California los angeles
Co-authored papers 5
Liubo Chen
The Second Affiliated Hospital of Zhejiang University
Co-authored papers 4
Xiangzhi Meng
University of California Los Angeles
Co-authored papers 4
Sumit K Chanda
The Scripps Research Institute
Co-authored papers 4
Jun Feng
University of California los angeles
Co-authored papers 4
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 3
Travis J Chapa
David Geffen School of Medicine, University of California los angeles
Co-authored papers 3
Xinghong Dai
Case Western Reserve University School of Medicine
Co-authored papers 3
Otto O Yang
Co-authored papers 3
Xin Yin
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Yuchen Xiao
University of California-Los Angeles
Co-authored papers 2
Dawei Zhao
Unmanned Systems Technology Research Center, Defense Innovation Institute
Co-authored papers 2
Lars Pache
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Jocelyn T Kim
University of California Los Angeles
Co-authored papers 2
Yafang Xie
Shanxi University
Co-authored papers 2
Yuan Pu
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Zugen Chen
David Geffen School of Medicine, University of California los angeles
Co-authored papers 2
Yen-Wen Tseng
University of California los angeles
Co-authored papers 2
Hongyu Deng
Cancer Research Institute, Central South University
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Release 1.2