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Author Details

Manolis Kellis
Massachusetts Institute of Technology
2003
263
105
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37645757Engineered 3D Immuno-Glial-Neurovascular Human miBrain Model.bioRxiv2024
37645757Engineered 3D Immuno-Glial-Neurovascular Human miBrain Model.bioRxiv2024
37961672Integrating single-cell RNA-seq datasets with substantial batch effects.bioRxiv2024
37961672Integrating single-cell RNA-seq datasets with substantial batch effects.bioRxiv2024
36420896GENCODE: reference annotation for the human and mouse genomes in 2023.Nucleic Acids Res2023
36420896GENCODE: reference annotation for the human and mouse genomes in 2023.Nucleic Acids Res2023
37738970SARS-CoV-2 variants evolve convergent strategies to remodel the host response.Cell2023
38014075An encyclopedia of enhancer-gene regulatory interactions in the human genome.bioRxiv2023
37907809Author Correction: Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease.Nat Neurosci2023
38092772Structural variants involved in high-altitude adaptation detected using single-molecule long-read sequencing.Nat Commun2023
37890495Power of inclusion: Enhancing polygenic prediction with admixed individuals.Am J Hum Genet2023
38064127Dissecting the tumor microenvironment in response to immune checkpoint inhibitors via single-cell and spatial transcriptomics.Clin Exp Metastasis2023
37774679Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration.Cell2023
37774680Epigenomic dissection of Alzheimer's disease pinpoints causal variants and reveals epigenome erosion.Cell2023
37774678Human microglial state dynamics in Alzheimer's disease progression.Cell2023
37774677Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer's disease pathology.Cell2023
37770633Multitissue H3K27ac profiling of GTEx samples links epigenomic variation to disease.Nat Genet2023
36650127Transcriptional vulnerabilities of striatal neurons in human and rodent models of Huntington's disease.Nat Commun2023
37264161Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease.Nat Neurosci2023
37075128Lateral mammillary body neurons in mouse brain are disproportionately vulnerable in Alzheimer's disease.Sci Transl Med2023
36697832Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.Nature2023
37058410Exercise training remodels inguinal white adipose tissue through adaptations in innervation, vascularization, and the extracellular matrix.Cell Rep2023
37491937Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.Am J Psychiatry2023
37491937Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.Am J Psychiatry2023
38014075An encyclopedia of enhancer-gene regulatory interactions in the human genome.bioRxiv2023
37907809Author Correction: Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease.Nat Neurosci2023
38064127Dissecting the tumor microenvironment in response to immune checkpoint inhibitors via single-cell and spatial transcriptomics.Clin Exp Metastasis2023
37890495Power of inclusion: Enhancing polygenic prediction with admixed individuals.Am J Hum Genet2023
37738970SARS-CoV-2 variants evolve convergent strategies to remodel the host response.Cell2023
37774679Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration.Cell2023
37774680Epigenomic dissection of Alzheimer's disease pinpoints causal variants and reveals epigenome erosion.Cell2023
37774678Human microglial state dynamics in Alzheimer's disease progression.Cell2023
37774677Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer's disease pathology.Cell2023
37770633Multitissue H3K27ac profiling of GTEx samples links epigenomic variation to disease.Nat Genet2023
38092772Structural variants involved in high-altitude adaptation detected using single-molecule long-read sequencing.Nat Commun2023
37058410Exercise training remodels inguinal white adipose tissue through adaptations in innervation, vascularization, and the extracellular matrix.Cell Rep2023
37075128Lateral mammillary body neurons in mouse brain are disproportionately vulnerable in Alzheimer's disease.Sci Transl Med2023
37264161Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease.Nat Neurosci2023
36697832Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.Nature2023
36650127Transcriptional vulnerabilities of striatal neurons in human and rodent models of Huntington's disease.Nat Commun2023
34663921Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer.Nat Biotechnol2022
35714196BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1.Sci Adv2022
35390286Immune genes outside immune cells for multiple sclerosis.Neuron2022
36170369Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.Sci Adv2022
35831657Standardized annotation of translated open reading frames.Nat Biotechnol2022
35994651A partnership between the lipid scramblase XK and the lipid transfer protein VPS13A at the plasma membrane.Proc Natl Acad Sci U S A2022
36198295Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells.Cell Metab2022
35474001Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes.Nature2022
36257931A synthetic transcription platform for programmable gene expression in mammalian cells.Nat Commun2022
36385529APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.Nature2022
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mlin.net LLC
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Stanford University.
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Vanderbilt-Ingram Cancer Center, Vanderbilt University
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The Picower Institute for Learning and Memory, Massachusetts Institute of Technology
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Yale University
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Broad Institute of MIT and Harvard
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Center for Epigenomics, University of California San Diego
Co-authored papers 13
Rush University Medical Center
Co-authored papers 12
Barcelona Institute of Science and Technology
Co-authored papers 12
Co-authored papers 12
Altius Institute for Biomedical Sciences
Co-authored papers 12
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Stanford University
Co-authored papers 9
Co-authored papers 8
Keck School of Medicine of USC
Co-authored papers 8
Co-authored papers 8
Broad Institute of MIT and Harvard
Co-authored papers 8
Uppsala University
Co-authored papers 8
Harvard University, USA Broad Institute, USA Harvard Stem Cell Institute
Co-authored papers 8
Lawrence Berkeley National Laboratory
Co-authored papers 7
Broad Institute of MIT and Harvard
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European Bioinformatics Institute
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