Author details

Full Name

Dan Wang

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36996170	Base editing rescue of spinal muscular atrophy in cells and in mice.		2023
37886602	Non-canonical amino acid incorporation into AAV5 capsid enhances lung transduction in mice.		2023
37280258	Durable contraception in the female domestic cat using viral-vectored delivery of a feline anti-MÃ¼llerian hormone transgene.		2023
37328037	C9orf72 poly(PR) aggregation in nucleus induces ALS/FTD-related neurodegeneration in cynomolgus monkeys.		2023
37014712	Rescue of GM3 synthase deficiency by spatially controlled, rAAV-mediated ST3GAL5 delivery.		2023
35322228	AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice.	Nature	2022
35585789	Gene-based therapeutics for rare genetic neurodevelopmental psychiatric disorders.	Mol Ther	2022
35857082	Ataluren suppresses a premature termination codon in an MPS I-H mouse.	Journal of Molecular Medicine	2022
34695545	AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway.	Mol Ther	2022
34725353	Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo.	Nature Communications	2021
33980714	Single-cell sequencing reveals suppressive transcriptional programs regulated by MIS/AMH in neonatal ovaries.	Proceedings of the National Academy of Sciences of the United States of America	2021
33714697	AAV-Mediated Gene Therapy for Glycosphingolipid Biosynthesis Deficiencies.	Trends in Molecular Medicine	2021
32775498	AAV-Genome Population Sequencing of Vectors Packaging CRISPR Components Reveals Design-Influenced Heterogeneity.	Molecular Therapy - Methods and Clinical Development	2020
32243786	CRISPR-Based Therapeutic Genome Editing: Strategies and InÂ Vivo Delivery by AAV Vectors.	Cell	2020
32405514	Bone-Targeting AAV-Mediated Gene Silencing in Osteoclasts for Osteoporosis Therapy.	Molecular Therapy - Methods and Clinical Development	2020
30710128	Adeno-associated virus vector as a platform for gene therapy delivery.	Nature Reviews Drug Discovery	2019
31728271	Gene Delivery to Nonhuman Primate Preimplantation Embryos Using Recombinant Adeno-Associated Virus.	Advanced Science	2019
30358470	Intrathecal Adeno-Associated Viral Vector-Mediated Gene Delivery for Adrenomyeloneuropathy.	Human Gene Therapy	2019
31232694	Single-cell sequencing of neonatal uterus reveals an Misr2+ endometrial progenitor indispensable for fertility.	eLife	2019
31273195	Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis.	Nature Communications	2019
31112525	Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity.	JCI Insight	2019
29596011	Slow Infusion of Recombinant Adeno-Associated Viruses into the Mouse Cerebrospinal Fluid Space.	Human gene therapy methods	2018
30397628	Adeno-Associated Virus Neutralizing Antibodies in Large Animals and Their Impact on Brain Intraparenchymal Gene Transfer.	Molecular Therapy - Methods and Clinical Development	2018
30102296	Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice.	Nature Biotechnology	2018
29766031	A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates.	Molecular Therapy - Methods and Clinical Development	2018
29398483	Taking a Hint from Structural Biology: To Better Understand AAV Transport across the BBB.	Molecular Therapy	2018
29379011	Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses.	Nature Communications	2018
29597895	In Vivo Genome Editing Partially Restores Alpha1-Antitrypsin in a Murine Model of AAT Deficiency.	Hum Gene Ther	2018
28137855	AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy.	Proceedings of the National Academy of Sciences of the United States of America	2017
28462820	Short DNA Hairpins Compromise Recombinant Adeno-Associated Virus Genome Homogeneity.	Molecular Therapy	2017
29024785	Slow Intrathecal Injection of rAAVrh10 Enhances its Transduction of Spinal Cord and Therapeutic Efficacy in a Mutant SOD1 Model of ALS.	Neuroscience	2017
26526960	Adeno-associated Virus Serotype Vectors Efficiently Transduce Normal Prostate Tissue and Prostate Cancer Cells.		2016
27434683	CNS-restricted Transduction and CRISPR/Cas9-mediated Gene Deletion with an Engineered AAV Vector.	Mol Ther Nucleic Acids	2016
26050084	A Single Injection of Recombinant Adeno-Associated Virus into the Lumbar Cistern Delivers Transgene Expression Throughout the Whole Spinal Cord.	Molecular Neurobiology	2016
26216943	AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.	Proceedings of the National Academy of Sciences of the United States of America	2015
26086867	Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.	Hum Gene Ther	2015
25091489	State-of-the-art human gene therapy: part I. Gene delivery technologies.		2014
24386892	The potential of adeno-associated viral vectors for gene delivery to muscle tissue.		2014
25227756	State-of-the-art human gene therapy: part II. Gene therapy strategies and clinical applications.		2014
23593225	Attenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppression.	PLoS ONE	2013
22056610	The designer aminoglycoside NB84 significantly reduces glycosaminoglycan accumulation associated with MPS I-H in the Idua-W392X mouse.	Molecular Genetics and Metabolism	2012
22672057	Suppression of premature termination codons as a therapeutic approach.	Critical Reviews in Biochemistry and Molecular Biology	2012
19751987	Characterization of an MPS I-H knock-in mouse that carries a nonsense mutation analogous to the human IDUA-W402X mutation.	Mol Genet Metab	2010