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Author Details

Nina Gustafsson
Karolinska Institutet
2005
16
10
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35228749Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.Nat Cancer2022
34298817PFKFB3 Inhibition Sensitizes DNA Crosslinking Chemotherapies by Suppressing Fanconi Anemia Repair.Cancers (Basel)2021
33810010Targeting CX3CR1 Suppresses the Fanconi Anemia DNA Repair Pathway and Synergizes with Platinum.Cancers (Basel)2021
34158617The γ-tubulin meshwork assists in the recruitment of PCNA to chromatin in mammalian cells.Commun Biol2021
31287536Societal costs of venous thromboembolism and subsequent major bleeding events: a national register-based study.Eur Heart J Qual Care Clin Outcomes2020
28976232Distinct mechanistic responses to replication fork stalling induced by either nucleotide or protein deprivation.Cell Cycle2018
30250201Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination.Nat Commun2018
30323634Societal costs due to meningococcal disease: a national registry-based study.Clinicoecon Outcomes Res2018
27899380Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor.Cancer Res2017
27530327NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine.Cancer Res2016
26461067The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation.Sci Rep2015
24451681Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer.Nat Commun2014
23042805Estrogen receptor-α, RBCK1, and protein kinase C β 1 cooperate to regulate estrogen receptor-α gene expression.J Mol Endocrinol2012
20103625RBCK1 drives breast cancer cell proliferation by promoting transcription of estrogen receptor alpha and cyclin B1.Cancer Res2010
19237537E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesis.Mol Cell Biol2009
15738425Inactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male mice.Proc Natl Acad Sci U S A2005
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Collaborators

Thomas Helleday
The University of Sheffield
Co-authored papers 5
P??l Stenmark
Stockholm University
Co-authored papers 3
Ann-Sofie Jemth
Karolinska Institutet
Co-authored papers 3
Mohit Jain
Cumming School of Medicine, University of Calgary, 0 Hospital Drive NW
Co-authored papers 2
Roland Nilsson
Karolinska Institutet
Co-authored papers 2
Maria H??ggblad
Karolinska Institute
Co-authored papers 2
Olga Loseva
Karolinska Institutet
Co-authored papers 2
Anna Asplund
Uppsala University
Co-authored papers 2
Lara Strittmatter
University of Massachusetts Chan Medical School
Co-authored papers 2
Jos Jonkers
Oncode Institute, Netherlands Cancer Institute
Co-authored papers 2
Kirsten M Robertson
Co-authored papers 1
Jesper Tegn??r
King Abdullah University of Science and Technology (KAUST)
Co-authored papers 1
Ulf Martens
Stockholm University
Co-authored papers 1
Megan Carter
Stockholm University
Co-authored papers 1
Vamsi K Mootha
Broad Institute of MIT and Harvard
Co-authored papers 1
Lisa Jarl
Karolinska Institutet
Co-authored papers 1
Caroline Kampf
Uppsala University
Co-authored papers 1
Nikhil Madhusudan
Co-authored papers 1
Anna Ehrlund
Karolinska Institutet
Co-authored papers 1
Angelika Schmidt
Institute for Immunology, Biomedical Center (BMC)
Co-authored papers 1
Karin Jirstr??m
Lund University
Co-authored papers 1
Judith E Unterlass
Karolinska Institute
Co-authored papers 1
Emma Lundberg (CM4AI)
Stanford University
Co-authored papers 1
Diana Mahdessian
KTH - Royal Institute of Technology
Co-authored papers 1
Stefan Knapp
Institute of Pharmaceutical Chemistry, Goethe University
Co-authored papers 1
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