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Author Details

Russell S Thomas
1995
168
55
PMIDPaper TitleJournal TitlePublished Year
37506331High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions.Annu Rev Pharmacol Toxicol2024
36742129Identifying xenobiotic metabolites with prediction tools and LCMS suspect screening analysis.2023
35460101A value of information framework for assessing the trade-offs associated with uncertainty, duration, and cost of chemical toxicity testing.Risk Analysis2023
37990691Reproducibility of organ-level effects in repeat dose animal studies.2023
37557933Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening.2023
37478680Cutting-edge computational chemical exposure research at the U.S. Environmental Protection Agency.2023
34490933A Framework that Considers the Impacts of Time, Cost, and Uncertainty in the Determination of the Cost Effectiveness of Toxicity-Testing Methodologies.Risk Analysis2022
35357465Assessing Safety Without Animal Testing: The Road Ahead.Toxicological Sciences2022
36969381Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing.2022
35172002Chemical Screening in an Estrogen Receptor Transactivation Assay With Metabolic Competence.Toxicological Sciences2022
33140634The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology.Chem Res Toxicol2021
34289070Estimating Hepatotoxic Doses Using High-Content Imaging in Primary Hepatocytes.Toxicological Sciences2021
33539251Bringing together scientific disciplines for collaborative undertakings: a vision for advancing the adverse outcome pathway framework.Int J Radiat Biol2021
33538836High-Throughput Transcriptomics Platform for Screening Environmental Chemicals.Toxicological Sciences2021
34333066Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology.Regul Toxicol Pharmacol2021
31532525Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization.Toxicological Sciences2020
32073639Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity.Toxicological Sciences2020
31808822Development of an In Vitro Human Thyroid Microtissue Model for Chemical Screening.Toxicological Sciences2020
32991717The Alginate Immobilization of Metabolic Enzymes Platform Retrofits an Estrogen Receptor Transactivation Assay With Metabolic Competence.Toxicological Sciences2020
32529217Corrigendum to: "Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity".Toxicological Sciences2020
31532498Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization.Toxicological Sciences2019
30218698Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system.Toxicology in Vitro2019
30570668Workflow for defining reference chemicals for assessing performance of in vitro assays.Altex2019
30329029BMDExpress 2: enhanced transcriptomic dose-response analysis workflow.Bioinformatics2019
30632786A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing.Environmental Health Perspectives2019
31501805Considerations for Strategic Use of High-Throughput Transcriptomics Chemical Screening Data in Regulatory Decisions.Curr Opin Toxicol2019
31202941Hexabromocyclododecane (HBCD): A case study applying tiered testing for human health risk assessment.Food Chem Toxicol2019
29405058Suspect Screening Analysis of Chemicals in Consumer Products.Environmental Science & Technology2018
30205137Evaluation of androgen assay results using a curated Hershberger database.Reproductive Toxicology2018
30205136Development of a curated Hershberger database.Reproductive Toxicology2018
30059008Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies.Environ Health Perspect2018
29529324The US Federal Tox21 Program: A strategic and operational plan for continued leadership.Altex2018
29385628Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics.Toxicological Sciences2018
29555536mRNA transfection retrofits cell-based assays with xenobiotic metabolism.2018
29600706Accelerating the Pace of Chemical Risk Assessment.Chemical Research in Toxicology2018
28123101Editor's Highlight: Application of Gene Set Enrichment Analysis for Identification of Chemically Induced, Biologically Relevant Transcriptomic Networks and Potential Utilization in Human Health Risk Assessment.Toxicological Sciences2017
28993267On selecting a minimal set of in vitro assays to reliably determine estrogen agonist activity.Regulatory Toxicology and Pharmacology2017
28768096Predicting Organ Toxicity Using in Vitro Bioactivity Data and Chemical Structure.Chemical Research in Toxicology2017
28767231Correction to Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model.Environmental Science & Technology2017
28520487Chemical Risk Assessment: Traditional vs Public Health Perspectives.American Journal of Public Health2017
27933809Development and Validation of a Computational Model for Androgen Receptor Activity.Chemical Research in Toxicology2017
27928627Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment.Arch Toxicol2017
28055944Comment on "On the Utility of ToxCastâ¿¢ and ToxPi as Methods for Identifying New Obesogens".Environmental Health Perspectives2017
27590929Immunological characterization of the aryl hydrocarbon receptor (AHR) knockout rat in the presence and absence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).Toxicology2016
27091369The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions.Environ Health Perspect2016
27367298ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology.Chemical Research in Toxicology2016
27174420Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information.Regulatory Toxicology and Pharmacology2016
27208079Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.Toxicol Sci2016
26473631Using ToxCastâ¿¢ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure.Environ Health Perspect2016
26671443BMDExpress Data Viewer - a visualization tool to analyze BMDExpress datasets.J Appl Toxicol2016
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