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Author Details

Hae-Ock Lee
College of Medicine, The Catholic University of Korea
1996
54
23
PMIDPaper TitleJournal TitlePublished Year
36797491Single-cell mapping of combinatorial target antigens for CAR switches using logic gates.Nat Biotechnol2023
37540709Association of cyclooxygenase-2 expression with endoplasmic reticulum stress and autophagy in triple-negative breast cancer.PLoS One2023
36623812Perspectives on single-nucleus RNA sequencing in different cell types and tissues.J Pathol Transl Med2023
36650700CTLA-4 inhibition facilitates follicular T and B cell interaction and the production of tumor-specific antibodies.Int J Cancer2023
35069539Granulocyte Macrophage-Colony Stimulating Factor Produces a Splenic Subset of Monocyte-Derived Dendritic Cells That Efficiently Polarize T Helper Type 2 Cells in Response to Blood-Borne Antigen.Front Immunol2022
35710446The regulation of insulin receptor/insulin-like growth factor 1 receptor ratio, an important factor for breast cancer prognosis, by TRIP-Br1.J Hematol Oncol2022
36397035Prescreening of tumor samples for tumor-centric transcriptome analyses of lung adenocarcinoma.BMC Cancer2022
363333422'-5' oligoadenylate synthetaseâ¿¿like 1 (OASL1) protects against atherosclerosis by maintaining endothelial nitric oxide synthase mRNA stability.Nat Commun2022
36115863Single-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia.Nat Commun2022
33983580Single Cell Genomics for Tumor Heterogeneity.Adv Exp Med Biol2021
34439827Clinical Perspectives of Single-Cell RNA Sequencing.Biomolecules2021
31558476Alterations in the Transcriptional Programs of Myeloma Cells and the Microenvironment during Extramedullary Progression Affect Proliferation and Immune Evasion.Clin Cancer Res2020
33277616Tumor-promoting macrophages prevail in malignant ascites of advanced gastric cancer.Exp Mol Med2020
32661348Cancer cells undergoing epigenetic transition show short-term resistance and are transformed into cells with medium-term resistance by drug treatment.Exp Mol Med2020
32883094Anti-Inflammatory Actions of Soluble Ninjurin-1 Ameliorate Atherosclerosis.Circulation2020
32934030Correction: Alterations in the Transcriptional Programs of Myeloma Cells and the Microenvironment during Extramedullary Progression Affect Proliferation and Immune Evasion.Clin Cancer Res2020
32385277Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma.Nat Commun2020
32460812Single-cell RNA sequencing reveals the tumor microenvironment and facilitates strategic choices to circumvent treatment failure in a chemorefractory bladder cancer patient.Genome Med2020
32451460Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer.Nat Genet2020
31100099Alternative polyadenylation of single cells delineates cell types and serves as a prognostic marker in early stage breast cancer.PLoS One2019
29208629SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells.Genome Res2018
29898899Linking transcriptional and genetic tumor heterogeneity through allele analysis of single-cell RNA-seq data.Genome Res2018
27409339Nonlinear tumor evolution from dysplastic nodules to hepatocellular carcinoma.Oncotarget2017
28474673Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer.Nat Commun2017
28263318Spatiotemporal genomic architecture informs precision oncology in glioblastoma.Nat Genet2017
28939741Tumor Heterogeneity Predicts Metastatic Potential in Colorectal Cancer.Clin Cancer Res2017
28985013HDAC2/3 binding and deacetylation of BubR1 initiates spindle assembly checkpoint silencing.FEBS J2017
28539161Single-cell RNA-Seq unveils tumor microenvironment.BMB Rep2017
27223072Comprehensive genomic profiling of IgM multiple myeloma identifies IRF4 as a prognostic marker.Oncotarget2016
27634910Recurrent mutations of MAPK pathway genes in multiple myeloma but not in amyloid light-chain amyloidosis.Oncotarget2016
27139883Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma.Genome Biol2016
25527510Standard immunohistochemistry efficiently screens for anaplastic lymphoma kinase rearrangements in differentiated thyroid cancer.Endocr Relat Cancer2015
26305796Identification of Distinct Tumor Subpopulations in Lung Adenocarcinoma via Single-Cell RNA-seq.PLoS One2015
26265110The use of FNA samples for whole-exome sequencing and detection of somatic mutations in breast cancer surgical specimens.Cancer Cytopathol2015
26155838The diagnostic application of targeted re-sequencing in Korean patients with retinitis pigmentosa.BMC Genomics2015
26084335Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells.Genome Biol2015
26023078Deregulation of Retinaldehyde Dehydrogenase 2 Leads to Defective Angiogenic Function of Endothelial Colony-Forming Cells in Pediatric Moyamoya Disease.Arterioscler Thromb Vasc Biol2015
25666348Brca2 deficiency leads to T cell loss and immune dysfunction.Mol Cells2015
23878276Loss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation.J Cell Biol2013
22340495BRCA2 fine-tunes the spindle assembly checkpoint through reinforcement of BubR1 acetylation.Dev Cell2012
22575646Cell density-dependent acetylation of οNp63α is associated with p53-dependent cell cycle arrest.FEBS Lett2012
20396962Fgfbp1 is essential for the cellular survival during zebrafish embryogenesis.Mol Cells2010
20553902Inhibition of Plk1 induces mitotic infidelity and embryonic growth defects in developing zebrafish embryos.Dev Biol2010
19158078Control of rapsyn stability by the CUL-3-containing E3 ligase complex.J Biol Chem2009
18023281SuPr-1-mediated desumoylation regulates the repressor activity of DeltaNp63alpha.FEBS Lett2007
18028447Regulation of DeltaNp63alpha by tumor necrosis factor-alpha in epithelial homeostasis.FEBS J2007
16616891A dominant negative form of p63 inhibits apoptosis in a p53-independent manner.Biochem Biophys Res Commun2006
12787569Biology of FasL.Cytokine Growth Factor Rev2003
12885868P-selectin and P-selectin glycoprotein ligand 1 are major determinants for Th1 cell recruitment to nonlymphoid effector sites in the intestinal lamina propria.J Exp Med2003
11937536The state of CD4+ T cell activation is a major factor for determining the kinetics and location of T cell responses to oral antigen.J Immunol2002
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Collaborators

Woong-Yang Park
Samsung Genome Institute, Samsung Medical Center
Co-authored papers 28
Nayoung K D Kim
Samsung Genome Institute, Samsung Medical Center
Co-authored papers 9
Kyu-Tae Kim
Ajou University
Co-authored papers 6
Do-Hyun Nam
Samsung Medical Center, Sungkyunkwan University School
Co-authored papers 4
Kyeung Min Joo
Cancer Stem Cell Research Center, Samsung Biomedical Research Institute
Co-authored papers 3
Hye Won Lee
Yonsei University College of Medicine, Severance Hospital
Co-authored papers 3
Joon Seol Bae
Research Institute of Future Medicine, Samsung Medical Center
Co-authored papers 3
Jung-Il Lee
Gangnam Severance Hospital
Co-authored papers 2
Sang Shin
Feinberg School of Medicine, Northwestern University
Co-authored papers 2
Sung Tae Kim
Busan Paik Hospital, Inje University
Co-authored papers 2
Byong Chang Jeong
Samsung Medical Center, Sungkyunkwan University School of Medicine
Co-authored papers 2
Jeong Eon Lee
Samsung Medical Center, Sungkyunkwan University School of Medicine
Co-authored papers 2
Yun Jee Seo
Institute for Refractory Cancer Research, Samsung Medical Center
Co-authored papers 2
Soohyun Lee
Co-authored papers 1
Seung Won Choi
Samsung Medical Center, Sungkyunkwan University
Co-authored papers 1
Seung-Ki Kim
Seoul National University Children's Hospital
Co-authored papers 1
Antonio Iavarone
Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami
Co-authored papers 1
In-Hee Lee
Co-authored papers 1
Pablo G Camara
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 1
Andrew X Chen
Columbia University
Co-authored papers 1
Junhyung Kim
Keimyung University School of Medicine
Co-authored papers 1
Daniel I S Rosenbloom
Merck & Co. Inc.
Co-authored papers 1
Ho Jun Seol
Samsung Medical Center, Sungkyunkwan University School of Medicine
Co-authored papers 1
Patrick van Nieuwenhuizen
Columbia University
Co-authored papers 1
Shyam Prabhakar
Genome Institute of Singapore (GIS)
Co-authored papers 1
Peter J Park
Harvard Medical School
Co-authored papers 1
Jeong-Won Lee
Samsung Medical Center, Sungkyunkwan University School of Medicine
Co-authored papers 1
Jin-Ku Lee
Seoul National University, College of Medicine
Co-authored papers 1
Sang Won Jung
Institute for Refractory Cancer Research
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Yeon-Lim Suh
Samsung Medical Center, Sungkyunkwan University College of Medicine
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Release 1.2