Author details

Full Name

Almer M van der Sloot

Affiliation

Institute for Research in Immunology and Cancer, Universite de Montreal

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36890145	A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay.	Sci Rep	2023
37797618	RECOVER identifies synergistic drug combinations inÂ vitro through sequential model optimization.	Cell Rep Methods	2023
34705497	Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex.	Sci Adv	2021
32785687	Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality.	J Cell Biol	2020
32094149	Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development.	Genetics	2020
30943680	A novel CHD7 mutation in an adolescent presenting with growth and pubertal delay.	Ann Pediatr Endocrinol Metab	2019
29144511	Evaluating CHARGE syndrome in congenital hypogonadotropic hypogonadism patients harboring CHD7 variants.	Genet Med	2018
29775575	At Long Last, a C-Terminal Bookend for the Ubiquitin Code.	Mol Cell	2018
29108999	Generation of rationally-designed nerve growth factor (NGF) variants with receptor specificity.	Biochem Biophys Res Commun	2018
28525738	Synthetic Genomics: Rewriting the Genome Chromosome by Chromosome.	Mol Cell	2017
26050621	Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity.	Oncogene	2016
23995386	Engineering of weak helper interactions for high-efficiency FRET probes.	Nat Methods	2013
22213832	Kinetics in signal transduction pathways involving promiscuous oligomerizing receptors can be determined by receptor specificity: apoptosis induction by TRAIL.	Mol Cell Proteomics	2012
22961987	The design and characterization of receptor-selective APRIL variants.	J Biol Chem	2012
22789664	An improved understanding of TNFL/TNFR interactions using structure-based classifications.	Trends Biochem Sci	2012
22539353	A novel classification system to predict the pathogenic effects of CHD7 missense variants in CHARGE syndrome.	Hum Mutat	2012
21153357	Computational design of TNF ligand-based protein therapeutics.	Adv Exp Med Biol	2011
21684149	Protein design with fragment databases.	Curr Opin Struct Biol	2011
21316780	Computational design of peptide ligands.	Trends Biotechnol	2011
21070598	Targeting AML through DR4 with a novel variant of rhTRAIL.	J Cell Mol Med	2011
20215443	Building blocks for protein interaction devices.	Nucleic Acids Res	2010
21368856	Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants.	Cell Death Dis	2010
20471393	T-RMSD: a fine-grained, structure-based classification method and its application to the functional characterization of TNF receptors.	J Mol Biol	2010
19236007	Enhancement of antitumor properties of rhTRAIL by affinity increase toward its death receptors.	Biochemistry	2009
19574296	Protein design in biological networks: from manipulating the input to modifying the output.	Protein Eng Des Sel	2009
18071905	RGD-avidin-biotin pretargeting to alpha v beta 3 integrin enhances the proapoptotic activity of TNF alpha related apoptosis inducing ligand (TRAIL).	Apoptosis	2008
18721749	Loop grafting of Bacillus subtilis lipase A: inversion of enantioselectivity.	Chem Biol	2008
18474604	DR4-selective tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) variants obtained by structure-based design.	J Biol Chem	2008
18383241	A novel genetic selection system for improved enantioselectivity of Bacillus subtilis lipase A.	Chembiochem	2008
16731632	Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor.	Proc Natl Acad Sci U S A	2006
15753368	RET-familial medullary thyroid carcinoma mutants Y791F and S891A activate a Src/JAK/STAT3 pathway, independent of glial cell line-derived neurotrophic factor.	Cancer Res	2005
15486023	Stabilization of TRAIL, an all-beta-sheet multimeric protein, using computational redesign.	Protein Eng Des Sel	2004
15174165	Mutational analysis of a key residue in the substrate specificity of a cephalosporin acylase.	Chembiochem	2004
12523966	Binding of phage displayed Bacillus subtilis lipase A to a phosphonate suicide inhibitor.	J Biotechnol	2003

1 - 34 of 34

Daniel Carbajo

Institut de Quimica Avancada de Catalunya (IQAC-CSIC)

Career Start Year 2011

Number of shared co-authors 0

Eric Paquet

University of Laval

Career Start Year 2007

Number of shared co-authors 0

Nir London

The Weizmann Institute of Science

Career Start Year 2007

Number of shared co-authors 1

Jaume Bonet

Institute of Bioengineering, Ecole Polytechnique Federale de Lausanne

Career Start Year 2006

Number of shared co-authors 1

Suwen Zhao

ShanghaiTech University, China iHuman Institute

Career Start Year 2006

Number of shared co-authors 1

Jianwei Che

Dana-Farber Cancer Institute

Career Start Year 2005

Number of shared co-authors 1

David Marciano

Stanford Cardiovascular Institute (L.W., Stanford University School of Medicine

Career Start Year 2003

Number of shared co-authors 1

Gerald H Lushington

Inc. 16 Dekalb Pike

Career Start Year 2002

Number of shared co-authors 0

Alan M Sandercock

MedImmune Ltd.

Career Start Year 2001

Number of shared co-authors 1

Evripidis Gavathiotis

Albert Einstein College of Medicine

Career Start Year 2000

Number of shared co-authors 1

Eric Feyfant

Schrodinger Inc.

Career Start Year 1997

Number of shared co-authors 1

Bissan Al-Lazikani

The University of Texas MD Anderson Cancer Center

Career Start Year 1997

Number of shared co-authors 1

Bj??rn G Voldborg

Technical University of Denmark

Career Start Year 1995

Number of shared co-authors 0

Aw Edith Chan

The Walter and Eliza Hall Institute of Medical Research

Career Start Year 1993

Number of shared co-authors 1

Marc Ferrer

National Institutes of Health, National Center for Advancing Translational Sciences

Career Start Year 1992

Number of shared co-authors 0

Zhiqiang An

Zhengzhou University

Career Start Year 1992

Number of shared co-authors 0

Herman W T van Vlijmen

Leiden Academic Centre for Drug Research (LACDR), Leiden University

Career Start Year 1988

Number of shared co-authors 1

Miriam Eisenstein

Weizmann Institute of Science

Career Start Year 1988

Number of shared co-authors 1

Steven C Almo

Albert Einstein College of Medicine

Career Start Year 1988

Number of shared co-authors 4

Roman Jerala

National Institute of Chemistry

Career Start Year 1988

Number of shared co-authors 1

Rob Hooft van Huijsduijnen

Vrije Universiteit Amsterdam (VU)

Career Start Year 1987

Number of shared co-authors 0

Diane Joseph-McCarthy

Boston University

Career Start Year 1987

Number of shared co-authors 0

Stuart L Schreiber

Broad Institute

Career Start Year 1985

Number of shared co-authors 0

Stefan Knapp

Institute of Pharmaceutical Chemistry, Goethe University

Career Start Year 1983

Number of shared co-authors 1

Tamar Unger

Weizmann Institute of Science

Career Start Year 1983

Number of shared co-authors 1

Ruben Abagyan

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California

Career Start Year 1981

Number of shared co-authors 0

Alexander Kamb

Inc. 30301 Agoura Rd.

Career Start Year 1979

Number of shared co-authors 0

Gianni Cesareni

University of Rome 'Tor Vergata'

Career Start Year 1976

Number of shared co-authors 2

James A Wells

Department of Pharmaceutical Chemistry, University of California San Francisco

Career Start Year 1974

Number of shared co-authors 3

Jens Meiler

Vanderbilt University

Career Start Year 1954

Number of shared co-authors 1

row(s) 1 - 30 of 30

Mike Tyers

Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal

Co-authored papers 6

Jasmin Coulombe-Huntington

Institute for Research in Immunology and Cancer, Universite de Montreal

Co-authored papers 3

Erik Verschueren

University of California San Francisco

Co-authored papers 2

Jan Paul Medema

Oncode Institute

Co-authored papers 1

Alexis Kaushansky

Seattle Children's Research Institute, University of Washington

Co-authored papers 1

Alan Aderem

Seattle Children's Research Institute

Co-authored papers 1

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

Michael P Rout

The Rockefeller University

Co-authored papers 1

Charles M Rice

Rockefeller University

Co-authored papers 1

Fred D Mast

Center for Global Infectious Disease Research, Seattle Children's Research Institute

Co-authored papers 1

Brian T Chait

The Rockefeller University

Co-authored papers 1

Nitin S Baliga

Institute for Systems Biology

Co-authored papers 1

Roelof Koster

Maastricht University Medical Center

Co-authored papers 1

Deborah Bartholdi

Co-authored papers 1

Anne Marinier

Institute for Research in Immunology and Cancer

Co-authored papers 1

John D Aitchison

Center for Global Infectious Disease Research, Seattle Children's Research Institute

Co-authored papers 1

Andrew Chatr-Aryamontri

Institute for Research in Immunology and Cancer (IRIC), University of Montreal

Co-authored papers 1

Arti T Navare

Center for Global Infectious Disease Research, Seattle Children's Research Institute

Co-authored papers 1

Richard Quinton

Newcastle-upon-Tyne Hospitals NHS Trust.

Co-authored papers 1

Christian De Geyter

Co-authored papers 1

1 - 20

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