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Author Details

Andrew T Magis
Institute for Systems Biology
2007
68
27
PMIDPaper TitleJournal TitlePublished Year
36945445Generally-healthy individuals with aberrant bowel movement frequencies show enrichment for microbially-derived blood metabolites associated with reduced kidney function.bioRxiv2024
36941332Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention.Nat Med2023
34489601Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19.Nat Biotechnol2022
35437729Personal Dense Dynamic Data Clouds Connect Systems Biomedicine to Scientific Wellness.Methods Mol Biol2022
35690059Heterogeneity in statin responses explained by variation in the human gut microbiome.Med2022
36357685Genome-microbiome interplay provides insight into the determinants of the human blood metabolome.Nat Metab2022
34373755Discovery of Small Molecule Bak Activator for Lung Cancer Therapy.Theranostics2021
33651715DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk.J Clin Invest2021
33594379Characteristics and Factors Associated with COVID-19 Infection, Hospitalization, and Mortality Across Race and Ethnicity.medRxiv2021
33619379Gut microbiome pattern reflects healthy ageing and predicts survival in humans.Nat Metab2021
33731896Author Correction: Gut microbiome pattern reflects healthy ageing and predicts survival in humans.Nat Metab2021
33608710Characteristics and Factors Associated With Coronavirus Disease 2019 Infection, Hospitalization, and Mortality Across Race and Ethnicity.Clin Infect Dis2021
34519531Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans.mSystems2021
34117230The geometry of clinical labs and wellness states from deeply phenotyped humans.Nat Commun2021
32434536Correction to: Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy.Mol Cancer2020
33171100Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19.Cell2020
33060586Health and disease markers correlate with gut microbiome composition across thousands of people.Nat Commun2020
33004987Untargeted longitudinal analysis of a wellness cohort identifies markers of metastatic cancer years prior to diagnosis.Sci Rep2020
32766585Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories.bioRxiv2020
32817414Multiomic blood correlates of genetic risk identify presymptomatic disease alterations.Proc Natl Acad Sci U S A2020
32698840Plasma levels of soluble ACE2are associated with sex, Metabolic Syndrome, and its biomarkers in a large cohort, pointing to a possible mechanism for increased severity in COVID-19.Crit Care2020
32471946Longitudinal analysis reveals transition barriers between dominant ecological states in the gut microbiome.Proc Natl Acad Sci U S A2020
31048771Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program.Sci Rep2019
31724055Multi-Omic Biological Age Estimation and Its Correlation With Wellness and Disease Phenotypes: A Longitudinal Study of 3,558 Individuals.J Gerontol A Biol Sci Med Sci2019
31662324Mcl-1 Interacts with Akt to Promote Lung Cancer Progression.Cancer Res2019
31477923Blood metabolome predicts gut microbiome α-diversity in humans.Nat Biotechnol2019
30971271Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy.Mol Cancer2019
28895585Habitual sleep duration and sleep duration variation are independently associated with body mass index.Int J Obes (Lond)2018
30080845Reply to "Precision medicine in the clouds".Nat Biotechnol2018
30044989A Multi-omic Association Study of Trimethylamine N-Oxide.Cell Rep2018
29227281Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy.J Clin Invest2018
28714965A wellness study of 108 individuals using personal, dense, dynamic data clouds.Nat Biotechnol2017
28381544Modulation of Bax and mTOR for Cancer Therapeutics.Cancer Res2017
28762642Genomic, Transcriptional, and Phenotypic Analysis of the Glucose Derepressed Clostridium beijerinckii Mutant Exhibiting Acid Crash Phenotype.Biotechnol J2017
26981544Sulfatide Preserves Insulin Crystals Not by Being Integrated in the Lattice but by Stabilizing Their Surface.J Diabetes Res2016
26004684Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy.Cancer Cell2015
29270443SNAPR: a bioinformatics pipeline for efficient and accurate RNA-seq alignment and analysis.IEEE Life Sci Lett2015
24650217Detection of 1α,25-dihydroxyvitamin D-regulated miRNAs in zebrafish by whole transcriptome sequencing.Zebrafish2014
25230299Small-molecule Bax agonists for cancer therapy.Nat Commun2014
25330348Measuring the effect of inter-study variability on estimating prediction error.PLoS One2014
24780592Design, synthesis, and biological evaluation of novel FAK scaffold inhibitors targeting the FAK-VEGFR3 protein-protein interaction.Eur J Med Chem2014
22292771A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.Anticancer Agents Med Chem2013
23824742Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.Cancer Res2013
23841915Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth.BMC Cancer2013
23935471Multi-study integration of brain cancer transcriptomes reveals organ-level molecular signatures.PLoS Comput Biol2013
23496976AUREA: an open-source software system for accurate and user-friendly identification of relative expression molecular signatures.BMC Bioinformatics2013
23272972Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo.Anticancer Agents Med Chem2013
22292772Mitoxantrone targets the ATP-binding site of FAK, binds the FAK kinase domain and decreases FAK, Pyk-2, c-Src, and IGF-1R in vitro kinase activities.Anticancer Agents Med Chem2013
22019628A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth.Exp Hematol2012
22966958The top-scoring 'N' algorithm: a generalized relative expression classification method from small numbers of biomolecules.BMC Bioinformatics2012
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Collaborators

Institute for Systems Biology
Co-authored papers 28
Center for Phenomic Health, The Buck Institute for Research on Aging
Co-authored papers 21
Institute for Systems Biology
Co-authored papers 12
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Co-authored papers 11
and School of Public Health, University of Michigan ann arbor
Co-authored papers 10
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Co-authored papers 7
Co-authored papers 6
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Co-authored papers 5
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Co-authored papers 4
China Pharmaceutical University
Co-authored papers 4
Institute of Systems Biology, University of Washington
Co-authored papers 4
Fred Hutchinson Cancer Research Center, USA Clinical Research Division
Co-authored papers 3
Metabolism and Clinical Nutrition, Oregon Health and Sciences University.
Co-authored papers 3
Fred Hutchinson Cancer Center
Co-authored papers 3
Co-authored papers 3
Seattle Children's Research Institute
Co-authored papers 2
University of Florida
Co-authored papers 2
Oregon Health & Science University
Co-authored papers 2
Co-authored papers 2
Hankuk University of Foreign Studies
Co-authored papers 2
Mayo Clinic
Co-authored papers 2
Co-authored papers 2
Institute for Systems Biology
Co-authored papers 2
Johns Hopkins University
Co-authored papers 2
School of Public Health, University of Pittsburgh
Co-authored papers 2
Benaroya Research Institute at Virginia Mason, Institute for Systems Biology, Sage Bionetworks, University of Illinois at Urbana-Champaign
Co-authored papers 2
Center for Musculoskeletal Health, University of California Davis School of Medicine
Co-authored papers 2
School of Public Health, Oregon Health & Science University-Portland State University
Co-authored papers 2
Nanjing Medical University
Co-authored papers 2
Institute for Systems Biology
Co-authored papers 2