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Author Details
Full Name
Patrick A Navas
Affiliation
University of Washington
ORCID
Career Start Year
1988
Papers
26
H Index
18
Expertise
CM4AI Collaborator
Nathan Sheffield (CM4AI)
PMID
Paper Title
Journal Title
Published Year
29486463
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.
Dement Geriatr Cogn Disord
2018
29486463
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.
Dement Geriatr Cogn Disord
2018
28783727
Genetic origins of the Minoans and Mycenaeans.
Nature
2017
28783727
Genetic origins of the Minoans and Mycenaeans.
Nature
2017
25580597
Genomic discovery of potent chromatin insulators for human gene therapy.
Nat Biotechnol
2015
25580597
Genomic discovery of potent chromatin insulators for human gene therapy.
Nat Biotechnol
2015
23673646
A European population in Minoan Bronze Age Crete.
Nat Commun
2013
23892237
Epigenetic signature and enhancer activity of the human APOE gene.
Hum Mol Genet
2013
23673646
A European population in Minoan Bronze Age Crete.
Nat Commun
2013
23892237
Epigenetic signature and enhancer activity of the human APOE gene.
Hum Mol Genet
2013
22955617
The accessible chromatin landscape of the human genome.
Nature
2012
22955617
The accessible chromatin landscape of the human genome.
Nature
2012
17224162
Systematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiation.
J Mol Biol
2007
17224162
Systematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiation.
J Mol Biol
2007
17571346
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
Nature
2007
17571346
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
Nature
2007
16514181
Investigations of a human embryonic globin gene silencing element using YAC transgenic mice.
Exp Biol Med (Maywood)
2006
16514181
Investigations of a human embryonic globin gene silencing element using YAC transgenic mice.
Exp Biol Med (Maywood)
2006
16791208
Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays.
Nat Methods
2006
16791208
Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays.
Nat Methods
2006
16055715
Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5'HS3 deletion mutations: implication for LCR chromatin architecture.
Mol Cell Biol
2005
16131492
{gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice.
J Biol Chem
2005
16055715
Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5'HS3 deletion mutations: implication for LCR chromatin architecture.
Mol Cell Biol
2005
16199858
Genome architecture of the human beta-globin locus affects developmental regulation of gene expression.
Mol Cell Biol
2005
16199858
Genome architecture of the human beta-globin locus affects developmental regulation of gene expression.
Mol Cell Biol
2005
16131492
{gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice.
J Biol Chem
2005
14506128
Mutation of a transcriptional motif of a distant regulatory element reduces the expression of embryonic and fetal globin genes.
Hum Mol Genet
2003
14506128
Mutation of a transcriptional motif of a distant regulatory element reduces the expression of embryonic and fetal globin genes.
Hum Mol Genet
2003
11971871
Activation of the beta-like globin genes in transgenic mice is dependent on the presence of the beta-locus control region.
Hum Mol Genet
2002
11971871
Activation of the beta-like globin genes in transgenic mice is dependent on the presence of the beta-locus control region.
Hum Mol Genet
2002
11545582
The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis.
J Mol Biol
2001
11545582
The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis.
J Mol Biol
2001
9885233
Correct function of the locus control region may require passage through a nonerythroid cellular environment.
Blood
1999
9885233
Correct function of the locus control region may require passage through a nonerythroid cellular environment.
Blood
1999
9817925
LCR-dependent gene expression in beta-globin YAC transgenics: detailed structural studies validate functional analysis even in the presence of fragmented YACs.
Hum Mol Genet
1998
9668524
beta-YAC transgenic mice for studying LCR function.
Ann N Y Acad Sci
1998
9632803
Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion.
Mol Cell Biol
1998
9817925
LCR-dependent gene expression in beta-globin YAC transgenics: detailed structural studies validate functional analysis even in the presence of fragmented YACs.
Hum Mol Genet
1998
9632803
Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion.
Mol Cell Biol
1998
9668524
beta-YAC transgenic mice for studying LCR function.
Ann N Y Acad Sci
1998
8692864
Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice.
Proc Natl Acad Sci U S A
1996
8692864
Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice.
Proc Natl Acad Sci U S A
1996
7539923
Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.
Proc Natl Acad Sci U S A
1995
8846046
Coexpression of epsilon, G gamma and A gamma globin mRNA in embryonic red blood cells from a single copy beta-YAC transgenic mouse.
Blood Cells Mol Dis
1995
7539923
Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.
Proc Natl Acad Sci U S A
1995
7642090
The position of integration affects expression of the A gamma-globin-encoding gene linked to HS3 in transgenic mice.
Gene
1995
8846046
Coexpression of epsilon, G gamma and A gamma globin mRNA in embryonic red blood cells from a single copy beta-YAC transgenic mouse.
Blood Cells Mol Dis
1995
7642090
The position of integration affects expression of the A gamma-globin-encoding gene linked to HS3 in transgenic mice.
Gene
1995
1499152
Variable copy number of macronuclear DNA molecules in Tetrahymena.
Dev Genet
1992
1499152
Variable copy number of macronuclear DNA molecules in Tetrahymena.
Dev Genet
1992
1 - 50 of 52
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Co-authored papers
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University of Washington
Co-authored papers
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Co-authored papers
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University of Washington
Co-authored papers
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University of Washington
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3
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Altius Institute for Biomedical Sciences
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3
Ericka M Johnson
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3
Hua Cao
Co-authored papers
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Dimitra M Lotakis
University of Michigan, C.S. Mott Children's Hospital, 1540 E. Hospital Dr. ann arbor
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Kristen Lee
Altius Institute for Biomedical Sciences
Co-authored papers
3
Robert E Thurman
University of Washington
Co-authored papers
3
Molly Weaver
University of Kentucky
Co-authored papers
3
Roland D Green
NimbleGen Systems Inc.
Co-authored papers
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Shane Neph
Altius Institute for Biomedical Sciences
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2
Michael S Kuehn
Co-authored papers
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Richard Sandstrom
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Co-authored papers
2
Andrew Haydock
Co-authored papers
2
Jeff Goldy
Co-authored papers
2
William Stafford Noble
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2
Brett E Johnson
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2
Michael A Singer
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Jason D Lieb
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