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Author Details

Patrick A Navas
University of Washington
1988
26
18
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
29486463Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.Dement Geriatr Cogn Disord2018
29486463Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.Dement Geriatr Cogn Disord2018
28783727Genetic origins of the Minoans and Mycenaeans.Nature2017
28783727Genetic origins of the Minoans and Mycenaeans.Nature2017
25580597Genomic discovery of potent chromatin insulators for human gene therapy.Nat Biotechnol2015
25580597Genomic discovery of potent chromatin insulators for human gene therapy.Nat Biotechnol2015
23673646A European population in Minoan Bronze Age Crete.Nat Commun2013
23892237Epigenetic signature and enhancer activity of the human APOE gene.Hum Mol Genet2013
23673646A European population in Minoan Bronze Age Crete.Nat Commun2013
23892237Epigenetic signature and enhancer activity of the human APOE gene.Hum Mol Genet2013
22955617The accessible chromatin landscape of the human genome.Nature2012
22955617The accessible chromatin landscape of the human genome.Nature2012
17224162Systematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiation.J Mol Biol2007
17224162Systematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiation.J Mol Biol2007
17571346Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.Nature2007
17571346Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.Nature2007
16514181Investigations of a human embryonic globin gene silencing element using YAC transgenic mice.Exp Biol Med (Maywood)2006
16514181Investigations of a human embryonic globin gene silencing element using YAC transgenic mice.Exp Biol Med (Maywood)2006
16791208Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays.Nat Methods2006
16791208Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays.Nat Methods2006
16055715Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5'HS3 deletion mutations: implication for LCR chromatin architecture.Mol Cell Biol2005
16131492{gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice.J Biol Chem2005
16055715Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5'HS3 deletion mutations: implication for LCR chromatin architecture.Mol Cell Biol2005
16199858Genome architecture of the human beta-globin locus affects developmental regulation of gene expression.Mol Cell Biol2005
16199858Genome architecture of the human beta-globin locus affects developmental regulation of gene expression.Mol Cell Biol2005
16131492{gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice.J Biol Chem2005
14506128Mutation of a transcriptional motif of a distant regulatory element reduces the expression of embryonic and fetal globin genes.Hum Mol Genet2003
14506128Mutation of a transcriptional motif of a distant regulatory element reduces the expression of embryonic and fetal globin genes.Hum Mol Genet2003
11971871Activation of the beta-like globin genes in transgenic mice is dependent on the presence of the beta-locus control region.Hum Mol Genet2002
11971871Activation of the beta-like globin genes in transgenic mice is dependent on the presence of the beta-locus control region.Hum Mol Genet2002
11545582The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis.J Mol Biol2001
11545582The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis.J Mol Biol2001
9885233Correct function of the locus control region may require passage through a nonerythroid cellular environment.Blood1999
9885233Correct function of the locus control region may require passage through a nonerythroid cellular environment.Blood1999
9817925LCR-dependent gene expression in beta-globin YAC transgenics: detailed structural studies validate functional analysis even in the presence of fragmented YACs.Hum Mol Genet1998
9668524beta-YAC transgenic mice for studying LCR function.Ann N Y Acad Sci1998
9632803Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion.Mol Cell Biol1998
9817925LCR-dependent gene expression in beta-globin YAC transgenics: detailed structural studies validate functional analysis even in the presence of fragmented YACs.Hum Mol Genet1998
9632803Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion.Mol Cell Biol1998
9668524beta-YAC transgenic mice for studying LCR function.Ann N Y Acad Sci1998
8692864Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice.Proc Natl Acad Sci U S A1996
8692864Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice.Proc Natl Acad Sci U S A1996
7539923Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.Proc Natl Acad Sci U S A1995
8846046Coexpression of epsilon, G gamma and A gamma globin mRNA in embryonic red blood cells from a single copy beta-YAC transgenic mouse.Blood Cells Mol Dis1995
7539923Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.Proc Natl Acad Sci U S A1995
7642090The position of integration affects expression of the A gamma-globin-encoding gene linked to HS3 in transgenic mice.Gene1995
8846046Coexpression of epsilon, G gamma and A gamma globin mRNA in embryonic red blood cells from a single copy beta-YAC transgenic mouse.Blood Cells Mol Dis1995
7642090The position of integration affects expression of the A gamma-globin-encoding gene linked to HS3 in transgenic mice.Gene1995
1499152Variable copy number of macronuclear DNA molecules in Tetrahymena.Dev Genet1992
1499152Variable copy number of macronuclear DNA molecules in Tetrahymena.Dev Genet1992
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Collaborators

University of Washington
Co-authored papers 19
Altius Institute for Biomedical Sciences
Co-authored papers 6
University of Washington
Co-authored papers 4
Co-authored papers 4
University of Washington
Co-authored papers 3
University of Washington
Co-authored papers 3
University of Washington
Co-authored papers 3
Altius Institute for Biomedical Sciences
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
University of Michigan, C.S. Mott Children's Hospital, 1540 E. Hospital Dr. ann arbor
Co-authored papers 3
Altius Institute for Biomedical Sciences
Co-authored papers 3
University of Washington
Co-authored papers 3
University of Kentucky
Co-authored papers 3
NimbleGen Systems Inc.
Co-authored papers 2
Altius Institute for Biomedical Sciences
Co-authored papers 2
Co-authored papers 2
Altius Institute for Biomedical Sciences
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
The University of Chicago
Co-authored papers 2
Institute for Systems Genetics, NYU School of Medicine
Co-authored papers 2
University of Massachusetts Chan Medical School
Co-authored papers 2
Allen Institute for Brain Science
Co-authored papers 2
University of Chicago, Gwen Knapp Center for Lupus Research.
Co-authored papers 2
University of Michigan Medical School ann arbor
Co-authored papers 2
Harvard Medical School
Co-authored papers 2